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Hematology Reports
Volume 10
Issue 3
10.4081/hr.2018.7394
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Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Brief Report

Essential Thrombocythemia, Hemolytic Anemia and Hepatic Cirrhosis: Could There Be an Association?

by
Nata Pratama Hardjo Lugito
1,*,
Andree Kurniawan
1,
Yohanes Chandra Kurniawan
2,
Enny Yacobus
2 and
Edwin Halim
2
1
Department of Internal Medicine, Faculty of Medicine, Pelita Harapan University, Boulevard Jendral Sudirman, Karawaci, Tangerang 15811, Banten, Indonesia
2
Faculty of Medicine, Pelita Harapan University, Tangerang 15811, Banten, Indonesia
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2018, 10(3), 7394; https://doi.org/10.4081/hr.2018.7394
Submission received: 2 September 2017 / Revised: 1 June 2018 / Accepted: 24 June 2018 / Published: 24 September 2018

Abstract

Vascular events are the most common clinical complication of essential thrombocythemia, leading to sign and symptoms of this disease. There are various sign and symptoms of essential thrombocythemia, such as thrombosis in artery or vein, and enlarged spleen. Portal hypertension and hepatic cirrhosis could be caused by essential thrombocythemia via intrahepatic thrombus. Anemia in essential thrombocythemia patient treated with hydroxyurea could be the side effect of bone marrow supression and also hydroxyurea induced hemolytic anemia. Association betweeen autoimmune hemolytic anemia and primary biliary cirrhosis or hepatic cirrhosis has been discussed. This case report presented an patient diagnosed with essential thrombocythemia. He later developed hepatic cirrhosis possibly caused by intra hepatic thrombus in the setting of hypercoagulabuility in myeloproliverative disorders. He also sufferred from anemia due to hydroxyurea induced hemolytic anemia. Association between autoimmune hepatic cirrhosis and autoimmune hemolytic anemia should also be considered in this patient.
Keywords: essential thrombocythemia; hemolytic anemia; hepatic cirrhosis; hydroxyurea essential thrombocythemia; hemolytic anemia; hepatic cirrhosis; hydroxyurea

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MDPI and ACS Style

Lugito, N.P.H.; Kurniawan, A.; Kurniawan, Y.C.; Yacobus, E.; Halim, E. Essential Thrombocythemia, Hemolytic Anemia and Hepatic Cirrhosis: Could There Be an Association? Hematol. Rep. 2018, 10, 7394. https://doi.org/10.4081/hr.2018.7394

AMA Style

Lugito NPH, Kurniawan A, Kurniawan YC, Yacobus E, Halim E. Essential Thrombocythemia, Hemolytic Anemia and Hepatic Cirrhosis: Could There Be an Association? Hematology Reports. 2018; 10(3):7394. https://doi.org/10.4081/hr.2018.7394

Chicago/Turabian Style

Lugito, Nata Pratama Hardjo, Andree Kurniawan, Yohanes Chandra Kurniawan, Enny Yacobus, and Edwin Halim. 2018. "Essential Thrombocythemia, Hemolytic Anemia and Hepatic Cirrhosis: Could There Be an Association?" Hematology Reports 10, no. 3: 7394. https://doi.org/10.4081/hr.2018.7394

APA Style

Lugito, N. P. H., Kurniawan, A., Kurniawan, Y. C., Yacobus, E., & Halim, E. (2018). Essential Thrombocythemia, Hemolytic Anemia and Hepatic Cirrhosis: Could There Be an Association? Hematology Reports, 10(3), 7394. https://doi.org/10.4081/hr.2018.7394

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