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Article

Preventing Transmission of Infectious Agents in the Pediatric in-Patients Hematology-Oncology Setting: What Is the Role for Nonpharmacological Prophylaxis?

by
Désirée Caselli
1,*,
Simone Cesaro
2,
Susanna Livadiotti
3,
Ottavio Ziino
4,
Olivia Paolicchi
1,
Giulio Zanazzo
5,
Giuseppe M. Milano
6,
Maria Licciardello
7,
Angelica Barone
8,
Monica Cellini
9,
De Santis Raffaella
10,
Mareva Giacchino
11,
Mario Renato Rossi
12,
Maurizio Aricò
1 and
Elio Castagnola
13 for the Infection Study Group of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)
1
Dipartimento Oncoematologia Pediatrica, Azienda Ospedaliero-Universitaria Meyer, Firenze, Italy
2
Oncoematologia Pediatrica, Verona, Italy
3
UO Immunoinfettivologia, DMP Ospedale Pediatrico Bambino Gesù, Roma, Italy
4
U.O. di Oncoematologia Pediatrica, ARNAS Ospedali Civico, G. Di Cristina e Benfratelli, Italy
5
U.O. Emato Oncologia Istituto per l'Infanzia, Trieste, Italy
6
Unit of Pediatric Oncology and Haematology, Ospedale S. Maria della Misericordia, A.O. di Perugia, Italy
7
Centro di Riferimento Regionale di Emato-Oncologia Pediatrica Azienda Ospedaliero Universitaria Policlinico Gaspare Rodolico Catania, Italy
8
Pediatria e Oncoematologia, Azienda Ospedaliero-Universitaria di Parma, Italy
9
Dipartimento Materno-Infantile, U.O. Oncoematologia Pediatrica, Azienda Ospedaliero-Universitaria Policlinico, Modena, Italy
10
Oncematologia Pediatrica, San Giovanni Rotondo, Italy
11
S.C. Oncoematologia Pediatrica, Az. Ospedaliera OIRM S. Anna, Torino, Italy
12
Department of Pediatric Hematology, San Gerardo Hospital, Monza, University of Milan-Bicocca, Milan, Italy
13
Infectious Diseases Unit, Department of Hematology and Oncology, G. Gaslini Children’s Hospital, Genoa, Italy
 
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*
Author to whom correspondence should be addressed.
Pediatr. Rep. 2011, 3(1), e9; https://doi.org/10.4081/pr.2011.e9
Submission received: 7 December 2010 / Accepted: 16 March 2011 / Published: 25 March 2011

Abstract

The most intensive chemotherapy regimens were used in the past for leukemia patients who were the main focus of trials on infections; today there are increasing numbers of children with solid cancer and considerable risk of infection who do receive intensive stand ard-dose chemotherapy. Despite a continuous will to protect the immune-compromised child from infections, evidence-based indications for intervention by non-pharmacological tools is still lacking in the pediatric hematology-oncology literature. Guidelines on standard precautions as well as precautions to avoid transmission of specific infectious agents are available. As a result of a consensus discussion, the Italian Association for Pediatric Hematology-Oncology (AIEOP) Cooperative Group centers agree that for children treated with chemotherapy both of these approaches should be implemented and vigorously enforced, while additional policies, including strict environmental isolation, should be restricted to patients with selected clinical conditions or complications. We present here a study by the working group on infectious diseases of AIEOP.
Keywords: leukemia; infections; chemotherapy; pediatrics leukemia; infections; chemotherapy; pediatrics

Share and Cite

MDPI and ACS Style

Caselli, D.; Cesaro, S.; Livadiotti, S.; Ziino, O.; Paolicchi, O.; Zanazzo, G.; Milano, G.M.; Licciardello, M.; Barone, A.; Cellini, M.; et al. Preventing Transmission of Infectious Agents in the Pediatric in-Patients Hematology-Oncology Setting: What Is the Role for Nonpharmacological Prophylaxis? Pediatr. Rep. 2011, 3, e9. https://doi.org/10.4081/pr.2011.e9

AMA Style

Caselli D, Cesaro S, Livadiotti S, Ziino O, Paolicchi O, Zanazzo G, Milano GM, Licciardello M, Barone A, Cellini M, et al. Preventing Transmission of Infectious Agents in the Pediatric in-Patients Hematology-Oncology Setting: What Is the Role for Nonpharmacological Prophylaxis? Pediatric Reports. 2011; 3(1):e9. https://doi.org/10.4081/pr.2011.e9

Chicago/Turabian Style

Caselli, Désirée, Simone Cesaro, Susanna Livadiotti, Ottavio Ziino, Olivia Paolicchi, Giulio Zanazzo, Giuseppe M. Milano, Maria Licciardello, Angelica Barone, Monica Cellini, and et al. 2011. "Preventing Transmission of Infectious Agents in the Pediatric in-Patients Hematology-Oncology Setting: What Is the Role for Nonpharmacological Prophylaxis?" Pediatric Reports 3, no. 1: e9. https://doi.org/10.4081/pr.2011.e9

APA Style

Caselli, D., Cesaro, S., Livadiotti, S., Ziino, O., Paolicchi, O., Zanazzo, G., Milano, G. M., Licciardello, M., Barone, A., Cellini, M., Raffaella, D. S., Giacchino, M., Rossi, M. R., Aricò, M., & Castagnola, E., for the Infection Study Group of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). (2011). Preventing Transmission of Infectious Agents in the Pediatric in-Patients Hematology-Oncology Setting: What Is the Role for Nonpharmacological Prophylaxis? Pediatric Reports, 3(1), e9. https://doi.org/10.4081/pr.2011.e9

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