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Microbiology Research
  • Microbiology Research is published by MDPI from Volume 11 Issue 2 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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  • Open Access

2 April 2012

Sero-Survey of Hepatitis B Surface Antigen amongst Pregnant Women Attending Infectious Disease Hospital Bayara, Bauchi State, Nigeria

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1
Department of Virology, Federal College of Veterinary and Medical Laboratory Technology, Vom, Nigeria
2
National Veterinary Research Institute, Vom, Nigeria
3
Department of Laboratory Services, Family Health International, Bauchi, Nigeria
4
Department of Medical Laboratory Sciences, University of Maiduguri, Nigeria

Abstract

Hepatitis B virus (HBV) continues to cause serious health problems in developing countries. Neonatal infection with HBV, which is often acquired during delivery, carries a high risk resulting in persistent infection. This research aims to detect the prevalence of Hepatitis B surface Antigen (HBsAg) among pregnant women in our location of study. One hundred and eighty (180) sera samples were screened among pregnant women aged 13-49, using standard enzyme-linked immunosorbent assay (ELISA) method. Structured questionnaire were administered to the subjects to obtain demographic and other relevant data. Overall result showed that 31 (17.2%) were found to be positive for HBsAg among the total subjects screened. The highest prevalence was found among those aged 20-29 with 11 (6.1%) seropositivity (χ2 = 7.902; P = 0.048). Considering occupational distribution of volunteer subjects, a high prevalence of 12 (6.7%); P < 0.05 was recorded among house wives, which shows a measure of significance compared to other women screened. Furthermore, based on various risk factors subjects with history of surgery and use of unsterilized sharp instruments recorded 15 (8.3%) prevalence (P = 0.233; P > 0.05). How ever, women in their second trimester of pregnancy recorded a higher prevalence of 23 (12.8%):(P = 0.080; P < 0.05). This study therefore emphasizes the public health importance of HBV among pregnant women and equally suggests that children born to women with Hepatitis B Virus, be closely monitored for infection beyond the one and the half years of age, this also calls for a proper enlightenment on the dangers posed by the virus, while a well designed vaccination schedule is advocated among the general population.

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