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Infectious Disease Reports
Volume 4
Issue 1
10.4081/idr.2012.e5
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Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
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Brief Report

No Clinical or Biological Difference between Chikungunya and Dengue Fever during the 2010 Gabonese Outbreak

by
Dieudonne Nkoghe
1,2,*,
Roland Fabrice Kassa Kassa
1,
Ulrich Bisvigou
3,
Mélanie Caron
1,
Gilda Grard
1 and
Eric Maurice Leroy
1,4
1
Unité des Maladies Virales Emergentes, Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon
2
Ministère de la Santé Publique, Libreville, Gabon
3
Unité de Biologie Médicale et de Santé Publique, Centre International de Recherches Médicales de Franceville, Gabon
4
MIVEGEC, Montpellier, France
*
Author to whom correspondence should be addressed.
Infect. Dis. Rep. 2012, 4(1), e5; https://doi.org/10.4081/idr.2012.e5
Submission received: 14 September 2011 / Revised: 29 October 2011 / Accepted: 27 December 2011 / Published: 3 January 2012
Versions Notes

Abstract

Chikungunya (CHIKV) and Dengue (DENV) viruses, both arboviruses, have caused multiple outbreaks worldwide. Their clinical features are poorly described in Africa and there is no comparative study, although Chikungunya is considered as a dengue-like disease. We conducted a comparative study of clinical and biological data from CHIKV and DENV positive patients during the 2010 Gabonese outbreak. Patients consulting with general symptoms and having laboratory confirmation for CHIKV or DENV were included. Clinical and biological data were recorded. Statistical analyses were performed using Epi Info. A P value < 0.05 was considered significant. In all, 270 CHIKV+, 53 DENV+ and 20 co-infected patients were included in the study. Headaches, hemorrhage, leukopenia and lymphopenia were significantly (P respectively 0.01, 0.001, 0.02 and 0.001) more frequent in DENV+ patients than in CHIKV+. There was no additive effect of the two viruses. These clinical and hematological disorders are non specific and cannot assist for the differential diagnosis. These diseases are clinically indistinguishable, and need for laboratory confirmation.
Keywords: Chikungunya; Dengue; Symptoms; Gabon Chikungunya; Dengue; Symptoms; Gabon

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MDPI and ACS Style

Nkoghe, D.; Kassa Kassa, R.F.; Bisvigou, U.; Caron, M.; Grard, G.; Leroy, E.M. No Clinical or Biological Difference between Chikungunya and Dengue Fever during the 2010 Gabonese Outbreak. Infect. Dis. Rep. 2012, 4, e5. https://doi.org/10.4081/idr.2012.e5

AMA Style

Nkoghe D, Kassa Kassa RF, Bisvigou U, Caron M, Grard G, Leroy EM. No Clinical or Biological Difference between Chikungunya and Dengue Fever during the 2010 Gabonese Outbreak. Infectious Disease Reports. 2012; 4(1):e5. https://doi.org/10.4081/idr.2012.e5

Chicago/Turabian Style

Nkoghe, Dieudonne, Roland Fabrice Kassa Kassa, Ulrich Bisvigou, Mélanie Caron, Gilda Grard, and Eric Maurice Leroy. 2012. "No Clinical or Biological Difference between Chikungunya and Dengue Fever during the 2010 Gabonese Outbreak" Infectious Disease Reports 4, no. 1: e5. https://doi.org/10.4081/idr.2012.e5

APA Style

Nkoghe, D., Kassa Kassa, R. F., Bisvigou, U., Caron, M., Grard, G., & Leroy, E. M. (2012). No Clinical or Biological Difference between Chikungunya and Dengue Fever during the 2010 Gabonese Outbreak. Infectious Disease Reports, 4(1), e5. https://doi.org/10.4081/idr.2012.e5

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