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Infectious Disease Reports, Volume 13, Issue 1

2021 March - 28 articles

Cover Story: The emerging trends in healthcare-associated infections and the community spread of highly transmissible diseases, such as the new coronavirus disease 2019 (COVID-19), necessitates the need for safe and efficient environmental cleaning and decontamination technologies to reduce the transmission of infections. In this study, we tested a photocatalytic reactor decontamination method to disinfect contaminated surfaces in a hospital and a laboratory setting. Our data showed that the photocatalytic reactor treatment resulted in more than 99% average reduction in bacterial growth and 98.5% average reduction in viral infectivity. This study demonstrates that there is potential efficacy in using photocatalytic reactors to clean surfaces and environments within hospitals, laboratories, and non-hospital facilities, and, consequently, they may reduce the spread of bacterial and viral infections. View this paper
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Articles (28)

  • Opinion
  • Open Access
13 Citations
7,324 Views
8 Pages

How to Treat COVID-19 Patients at Home in the Italian Context: An Expert Opinion

  • Davide Roberto Donno,
  • Ignazio Grattagliano,
  • Alessandro Rossi,
  • Pierangelo Lora Aprile,
  • Gerardo Medea,
  • Erik Lagolio,
  • Guido Granata,
  • Nicola Petrosillo and
  • Claudio Cricelli

20 March 2021

The impact of the coronavirus disease (COVID-19), caused by the novel coronavirus SARS-CoV-2, continues to be widespread, with more than 100 million cases diagnosed in more than 220 countries since the virus was first identified in January 2020. Alth...

  • Article
  • Open Access
9 Citations
7,277 Views
12 Pages

A Dynamic Bayesian Model for Identifying High-Mortality Risk in Hospitalized COVID-19 Patients

  • Amir Momeni-Boroujeni,
  • Rachelle Mendoza,
  • Isaac J. Stopard,
  • Ben Lambert and
  • Alejandro Zuretti

18 March 2021

As Coronavirus Disease 2019 (COVID-19) hospitalization rates remain high, there is an urgent need to identify prognostic factors to improve patient outcomes. Existing prognostic models mostly consider the impact of biomarkers at presentation on the r...

  • Article
  • Open Access
11 Citations
3,974 Views
9 Pages

14 March 2021

Background: Kytococcus schroeteri is a member of normal skin microflora, which can cause lethal infections in immunosuppressed hosts. In this review we attempted to draw patterns of its pathogenicity, which seem to vary regarding host immune status a...

  • Article
  • Open Access
5 Citations
3,232 Views
11 Pages

Characterization of Neonatal Infections by Gram-Negative Bacilli and Associated Risk Factors, Havana, Cuba

  • Arlenis Oliva,
  • Yenisel Carmona,
  • Elizabeth de La C. López,
  • Roberto Álvarez,
  • Meiji Soe Aung,
  • Nobumichi Kobayashi and
  • Dianelys Quiñones

9 March 2021

Infections represent an important problem in neonates because of the high mortality. An increase in neonatal infections has been found in Cuban hospitals in recent years. The aim of this study was to provide evidence on the clinical and microbiologic...

  • Case Report
  • Open Access
3 Citations
4,096 Views
4 Pages

North Italy: Welcome to the Tropics!

  • Federica Veronese,
  • Francesca Graziola,
  • Pamela Farinelli,
  • Elisa Zavattaro,
  • Vanessa Tarantino,
  • Elia Esposto and
  • Paola Savoia

5 March 2021

We describe a case of cutaneous Larva Migrans in an 8-year-old Caucasian girl. The lesion appeared ten days after a bath in the river in a valley in the north-east of Piedmont. The patient was successfully treated with Albendazole 400 mg daily for 5...

  • Article
  • Open Access
8 Citations
5,003 Views
8 Pages

1 March 2021

The rapid identification of bacteria causing meningitis is crucial as delays in the treatment increase mortality rate. Though considered as the gold standard for the laboratory diagnosis of bacterial meningitis, culture might give false negative resu...

  • Case Report
  • Open Access
7 Citations
7,211 Views
6 Pages

Intracranial Tuberculoma Mimicking Neurosarcoidosis: A Clinical Challenge

  • Fatemah Abbasi,
  • Muhammet Ozer,
  • Kirti Juneja,
  • Suleyman Yasin Goksu,
  • Babak Jamasian Mobarekah and
  • Marc S. Whitman

1 March 2021

Central nervous system (CNS) tuberculosis is a rare manifestation of all tuberculosis presentations. The incidence of brain tuberculoma is increasing in developed countries due to HIV infection and immigration from tuberculosis-endemic countries. Sym...

  • Case Report
  • Open Access
10 Citations
3,681 Views
4 Pages

Deranged Coagulation Profile Secondary to Cefazolin Use: Case Report

  • Jinghao Nicholas Ngiam,
  • Tze Sian Liong,
  • Sai Meng Tham,
  • Thanawin Pramotedham,
  • Rawan AlAgha,
  • Joy Yong,
  • Paul Anantharajah Tambyah and
  • Lionel Hon Wai Lum

1 March 2021

Cefazolin is a widely used first-generation cephalosporin. While generally well tolerated, several case reports have described severe coagulopathy induced by intravenous (IV) cefazolin. This was seen particularly in patients with impaired renal funct...

  • Article
  • Open Access
13 Citations
3,816 Views
14 Pages

Nasopharyngeal Carriage of Methicillin-Resistant Staphylococcus aureus (MRSA) among Sickle Cell Disease (SCD) Children in the Pneumococcal Conjugate Vaccine Era

  • Nicholas T. K. D. Dayie,
  • Deborah N. K. Sekoh,
  • Fleischer C. N. Kotey,
  • Beverly Egyir,
  • Patience B. Tetteh-Quarcoo,
  • Kevin Kofi Adutwum-Ofosu,
  • John Ahenkorah,
  • Mary-Magdalene Osei and
  • Eric S. Donkor

1 March 2021

The aim of this cross-sectional study was to investigate Staphylococcus aureus nasopharyngeal carriage epidemiology in relation to other nasopharyngeal bacterial colonizers among sickle cell disease (SCD) children about five years into pneumococcal c...

  • Article
  • Open Access
3 Citations
3,599 Views
10 Pages

1 March 2021

To date, there is only one published report of an outbreak of urinary tract infections by Salmonella species after cystoscopy. Disinfection procedures for cystoscope have come into question. The current study aimed to determine the odds of developing...

  • Communication
  • Open Access
14 Citations
3,712 Views
7 Pages

Seroprevalence and Molecular Detection of Brucellosis in Hospitalized Patients in Lahore Hospitals, Pakistan

  • Riffat Yousaf,
  • Iahtasham Khan,
  • Wasim Shehzad,
  • Riaz Hussain,
  • Shahzad Ali,
  • Heinrich Neubauer and
  • Gamal Wareth

8 February 2021

Brucellosis is one of the most notorious zoonoses worldwide. The disease is common and endemic in humans and animals of Pakistan, but lack of awareness and lack of research have resulted in an increased incidence in the human population. The present...

  • Article
  • Open Access
8 Citations
4,505 Views
10 Pages

Prevalence and Determinants of Medication Adherence among Patients with HIV/AIDS in Southern Vietnam

  • Phuong M. Nguyen,
  • Anh N. Thach,
  • Xuan D. Pham,
  • Anh N. Lam,
  • Thao N. P. Nguyen,
  • Chu X. Duong,
  • Lam V. Nguyen,
  • Thao H. Nguyen,
  • Suol T. Pham and
  • Thang Nguyen
  • + 1 author

5 February 2021

This study was conducted to determine the prevalence and determinants of medication adherence among patients with HIV/AIDS in southern Vietnam. Methods: A cross-sectional study was conducted in a hospital in southern Vietnam from June to December 201...

  • Article
  • Open Access
2 Citations
4,389 Views
12 Pages

5 February 2021

This study explores the contribution of counseling to improving acceptance of and adherence to anti-retroviral therapy (ART) among people living with HIV (PLHIV) and identifies key issues associated with its implementation. We conducted a longitudina...

  • Article
  • Open Access
36 Citations
6,313 Views
13 Pages

Implications of the COVID-19 Lockdown on Dengue Transmission in Malaysia

  • Song-Quan Ong,
  • Hamdan Ahmad and
  • Ahmad Mohiddin Mohd Ngesom

5 February 2021

We aim to investigate the effect of large-scale human movement restrictions during the COVID-19 lockdown on both the dengue transmission and vector occurrences. This study compared the weekly dengue incidences during the period of lockdown to the pre...

  • Brief Report
  • Open Access
55 Citations
4,015 Views
6 Pages

Presence of SARS-CoV-2 RNA in Semen—Cohort Study in the United States COVID-19 Positive Patients

  • Bruno Machado,
  • Gustavo Barcelos Barra,
  • Nickolas Scherzer,
  • Jack Massey,
  • Hemerson dos Santos Luz,
  • Rafael Henrique Jacomo,
  • Ticiane Herinques Santa Rita and
  • Rodney Davis

4 February 2021

On 31 December 2019, China informed the World Health Organization they were facing a viral pneumonia epidemic of a new type of Coronavirus. Currently, 10 months later, more than 43,000,000 people have been infected, and about 1,150,000 deceased world...

  • Review
  • Open Access
26 Citations
9,850 Views
24 Pages

SARS–CoV-2 Immuno-Pathogenesis and Potential for Diverse Vaccines and Therapies: Opportunities and Challenges

  • Andrew R. McGill,
  • Roukiah Khalil,
  • Rinku Dutta,
  • Ryan Green,
  • Mark Howell,
  • Subhra Mohapatra and
  • Shyam S. Mohapatra

4 February 2021

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel coronavirus that emerged from Wuhan, China in late 2019 causing coronavirus disease-19 (COVID-19). SARS-CoV-2 infection begins by attaching to angiotensin-converting enzyme 2 rec...

  • Case Report
  • Open Access
7 Citations
5,832 Views
7 Pages

Intramedullary Conus Medullaris Tuberculoma: A Case Report and Review of the Literature

  • Verajit Chotmongkol,
  • Chinadol Wanitpongpun,
  • Warinthorn Phuttharak and
  • Sittichai Khamsai

15 January 2021

Intramedullary tuberculoma (IMT) of the conus medullaris is extremely rare. We present a case of intramedullary conus medullaris tuberculoma in which the diagnosis was based on there being very high levels of adenosine deaminase (ADA) in the patient&...

  • Article
  • Open Access
6 Citations
4,312 Views
7 Pages

Frequency of Hepatitis B, C and HIV Infections among Transfusion-Dependent Beta Thalassemia Patients in Dhaka

  • Golam Sarower Bhuyan,
  • Aftab Uz Zaman Noor,
  • Rosy Sultana,
  • Farjana Akther Noor,
  • Nusrat Sultana,
  • Suprovath Kumar Sarker,
  • Muhammad Tarikul Islam,
  • Md. Abu Sayeed,
  • Md. Imam Ul Khabir and
  • Kaiissar Mannoor
  • + 6 authors

15 January 2021

Transfusion transmitted infections have remained a major deterrent to public health, particularly among the patients with transfusion-dependent Beta thalassemia in developing countries. Although proper donor selection through adoption of WHO-advised...

  • Case Report
  • Open Access
1 Citations
2,978 Views
10 Pages

Idiopathic CD4 T Cell Lymphocytopenia: A Case of Overexpression of PD-1/PDL-1 and CTLA-4

  • Gaurav Kumar,
  • Heidy Schmid-Antomarchi,
  • Annie Schmid-Alliana,
  • Michel Ticchioni and
  • Pierre-Marie Roger

13 January 2021

Idiopathic CD4 T cell lymphocytopenia (ICL) is a rare entity characterized by CD4 T cell count of <300 cells/mm3 along with opportunistic infection for which T cell marker expression remains to be fully explored. We report an ICL case for which T...

  • Article
  • Open Access
4 Citations
6,463 Views
14 Pages

11 January 2021

Contaminated surfaces and indoor environments are important sources of infectious spread within hospital and non-hospital facilities. Bacterial infections such as infections with Clostridioides (formerly Clostridium) difficile (C. difficile) and Stap...

  • Article
  • Open Access
25 Citations
7,002 Views
13 Pages

7 January 2021

This paper provides a summary of mass COVID-19 testing of almost the entire population in Slovakia by antigen tests. We focused on the results delivered by two testing rounds and analyzed the benefits and weaknesses of such type of testing. We prepar...

  • Article
  • Open Access
7 Citations
4,814 Views
12 Pages

Incidence of Antibiotic Treatment Failure in Patients with Nursing Home-Acquired Pneumonia and Community Acquired Pneumonia

  • Mariana Lopes,
  • Gonçalo Alves Silva,
  • Rui Filipe Nogueira,
  • Daniela Marado,
  • João Gonçalves,
  • Carlos Athayde,
  • Dilva Silva,
  • Ana Figueiredo,
  • Jorge Fortuna and
  • Armando Carvalho

5 January 2021

Purpose: Nursing home-acquired pneumonia (NHAP) patients are at higher risk of multi-drug resistant infection (MDR) than those with community-acquired pneumonia (CAP). Recent evidence suggests a single risk factor for MDR does not accurately predict...

  • Case Report
  • Open Access
10 Citations
5,260 Views
10 Pages

Acute Brucellosis with a Guillain-Barre Syndrome-Like Presentation: A Case Report and Literature Review

  • Ali Alanazi,
  • Sara Al Najjar,
  • Jnadi Madkhali,
  • Yaser Al Malik,
  • Athal Al-Khalaf and
  • Ahmad Alharbi

1 January 2021

Introduction: Brucellosis is a zoonotic disease that can affect the central and peripheral nervous system and it has variable neurological manifestation. However, brucellosis infection that presents with acute peripheral neuropathy mimicking Guillain...

  • Case Report
  • Open Access
2 Citations
3,311 Views
7 Pages

Portal Dissemination of Fusarium graminearum in a Patient with Acute Lymphoblastic Leukemia and Febrile Neutropenia

  • Mary Gabriela Uscamayta,
  • Alexandra Martin-Onraet,
  • Karla Espinosa-Bautista,
  • Roberto Herrera-Goepfert,
  • Rigoberto Hernández-Castro and
  • Carolina Perez-Jimenez

1 January 2021

We present the case of a man with acute lymphoblastic leukemia and prolonged profound neutropenia, who developed an invasive infection by Fusarium graminearum, acquired via non-cutaneous entry, with gastrointestinal symptoms, sigmoid perforation and...

  • Article
  • Open Access
4 Citations
3,301 Views
5 Pages

Prevalence of Clostridioides difficile Infection in Critically Ill Patients with Extreme Leukocytosis and Diarrhea

  • Bijan Teja,
  • Nafeesa Alibhai,
  • Gordon D. Rubenfeld,
  • Linda R. Taggart,
  • Naheed Jivraj,
  • Sameer A. Hirji,
  • Brian P. O’Gara and
  • Shahzad Shaefi

1 January 2021

While early empiric antibiotic therapy is beneficial for patients presenting with sepsis, the presentation of sepsis from Clostridioides difficile (formerly Clostridium difficile) infection (CDI) has not been well studied in large cohorts. We sought...

  • Case Report
  • Open Access
4 Citations
5,894 Views
3 Pages

Angioedema and COVID-19: A New Dermatological Manifestation?

  • Pierre-Yves Royer,
  • Souheil Zayet,
  • Claire Jacquin-Porretaz,
  • N’dri Juliette Kadiane-Oussou,
  • Lynda Toko,
  • Vincent Gendrin and
  • Timothée Klopfenstein

1 January 2021

The main localization of SARS-CoV-2 infection is the respiratory tract. Digestive and otorhinolaryngological localizations are also reported. More recently, dermatological manifestations have been reported during Coronavirus disease-19 (COVID-19). We...

  • Case Report
  • Open Access
7 Citations
6,473 Views
7 Pages

1 January 2021

Primary spontaneous bacterial peritonitis (SBP) is a rare cause of acute abdomen in previously healthy patients, even more unusually caused by a group A Streptococcus (GAS) (also known as Streptococcus pyogenes) infection. We report a young, otherwis...

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Infect. Dis. Rep. - ISSN 2036-7449