- Perspective
Opportunities for and Challenges of Conducting Indirect Treatment Comparisons and Meta-Analyses for Vaccines in Post-EU HTA Regulation Era
- Charlotte Graham,
- Erin Barker,
- Joe Moss,
- Emily Gregg,
- Rachael McCool,
- Nathalie Largeron,
- Mélanie Trichard,
- José Bartelt-Hofer and
- Maribel Tribaldos
The dynamic nature of infectious diseases introduces inherent challenges to the design of vaccine clinical trials, which consequently makes vaccine indirect treatment comparisons (ITCs) and meta-analyses (MAs) more challenging compared with regular p...