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Volume 11
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10.1080/20016689.2023.2270293
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Journal of Market Access & Health Policy (JMAHP) is published by MDPI from Volume 12 Issue 1 (2024). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Taylor & Francis.
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Article

Observational Study on the Therapeutic Management and Economic Burden of Adult Patients with Moderate to Severe Plaque Psoriasis in France—The POP Study

by
A. P. Villani
1,†,
N. Quiles Tsimaratos
2,†,
A. Crochard
3,
A. Gherardi
3,
A. Panes
4,
A. Schmidt
4,
M. Hueber Kollen
3,* and
I. Borget
5
1
Department of Dermatology, Edouard Herriot Hospital Center, Lyon, France
2
Department of Dermatology, Saint-Joseph Hospital Center, Marseille, France
3
UCB Pharma SA, Défense Ouest, 420 rue d’Estienne d’Orves, Colombes Cedex 92705, France
4
HEVA, Lyon, France
5
Biostatistics and Epidemiology office, Gustave Roussy, Paris-Saclay University, Villejuif, France
*
Author to whom correspondence should be addressed.
†
Both authors contributed equally.
J. Mark. Access Health Policy 2023, 11(1), 2270293; https://doi.org/10.1080/20016689.2023.2270293
Submission received: 11 May 2023 / Revised: 3 October 2023 / Accepted: 9 October 2023 / Published: 1 November 2023

Abstract

ABSTRACT Background: Data on the therapeutic management and healthcare cost of moderate to severe psoriasis in France are scarce. Objective: To assess the therapeutic management and economic burden of patients with moderate to severe psoriasis. Setting: This is a retrospective observational study on the Generalist Beneficiaries Sample of the National Health Data System. Patients and outcome measures: Adults with moderate to severe psoriasis (with a topical vitamin D derivative followed by systemic treatment or hospitalization for psoriasis) were included and followed-up from 1 January 2009 to 31 December 2018. Patients were matched to controls without psoriasis. Patients’ characteristics and healthcare cost from the National Health Insurance’s (NHI) perspective were described. Results: Overall, 1,848 and 5,544 adults were included in the psoriatic and control cohorts, respectively. The most frequent treatments were methotrexate (18.5% to 21.4% of patients by year), phototherapy (29.9% in 2010 down to 6.2% in 2018), and acitretin (25.9% in 2010 down to 8.6% in 2018). Overall, 19% of patients used biotherapies. The mean healthcare costs reimbursed by NHI was €5,365/psoriatic patient (including €2,685 potentially attributable to psoriasis), which was twice as high as in controls. In both cohorts, healthcare costs increased over time. Conclusion: Moderate to severe psoriasis healthcare costs are high.
Keywords: psoriasis; epidemiology; cost; France psoriasis; epidemiology; cost; France

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MDPI and ACS Style

Villani, A.P.; Quiles Tsimaratos, N.; Crochard, A.; Gherardi, A.; Panes, A.; Schmidt, A.; Hueber Kollen, M.; Borget, I. Observational Study on the Therapeutic Management and Economic Burden of Adult Patients with Moderate to Severe Plaque Psoriasis in France—The POP Study. J. Mark. Access Health Policy 2023, 11, 2270293. https://doi.org/10.1080/20016689.2023.2270293

AMA Style

Villani AP, Quiles Tsimaratos N, Crochard A, Gherardi A, Panes A, Schmidt A, Hueber Kollen M, Borget I. Observational Study on the Therapeutic Management and Economic Burden of Adult Patients with Moderate to Severe Plaque Psoriasis in France—The POP Study. Journal of Market Access & Health Policy. 2023; 11(1):2270293. https://doi.org/10.1080/20016689.2023.2270293

Chicago/Turabian Style

Villani, A. P., N. Quiles Tsimaratos, A. Crochard, A. Gherardi, A. Panes, A. Schmidt, M. Hueber Kollen, and I. Borget. 2023. "Observational Study on the Therapeutic Management and Economic Burden of Adult Patients with Moderate to Severe Plaque Psoriasis in France—The POP Study" Journal of Market Access & Health Policy 11, no. 1: 2270293. https://doi.org/10.1080/20016689.2023.2270293

APA Style

Villani, A. P., Quiles Tsimaratos, N., Crochard, A., Gherardi, A., Panes, A., Schmidt, A., Hueber Kollen, M., & Borget, I. (2023). Observational Study on the Therapeutic Management and Economic Burden of Adult Patients with Moderate to Severe Plaque Psoriasis in France—The POP Study. Journal of Market Access & Health Policy, 11(1), 2270293. https://doi.org/10.1080/20016689.2023.2270293

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