Template-assisted, Sol-gel Fabrication of Biocompatible, Hierarchically Porous Hydroxyapatite Scaffolds
Abstract
:1. Introduction
2. Materials and Methods
2.1. Materials
Hydroxyapatite Scaffold Fabrication
2.2. Materials Characterization
2.3. Protein Adsorption
2.4. Cell Culture
3. Results and discussion
3.1. Open Porous Structure
3.2. Nanoscale Porous Structure
3.3. Crystallization and Mechanical Properties
3.4. Protein Adsorption
3.5. Cell Proliferation and Biocompatibility
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Characters | CHA | HHA | HHA—1 day in PBS | HHA—3 days in PBS | HHA—7 days in PBS | HHA—14 days in PBS |
---|---|---|---|---|---|---|
Porosity (%) | 89 | 95 | 97 | 98 | 98 | 98 |
Compressive strength (kPa) | 210 ± 20 | 81 ± 10 | 32 ± 8 | 26 ± 8 | 28 ± 9 | 26 ± 8 |
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Zhang, X.; Zhang, L.; Li, Y.; Hua, Y.; Li, Y.; Li, W.; Li, W. Template-assisted, Sol-gel Fabrication of Biocompatible, Hierarchically Porous Hydroxyapatite Scaffolds. Materials 2019, 12, 1274. https://doi.org/10.3390/ma12081274
Zhang X, Zhang L, Li Y, Hua Y, Li Y, Li W, Li W. Template-assisted, Sol-gel Fabrication of Biocompatible, Hierarchically Porous Hydroxyapatite Scaffolds. Materials. 2019; 12(8):1274. https://doi.org/10.3390/ma12081274
Chicago/Turabian StyleZhang, Xingyuan, Lirong Zhang, Yuanwei Li, Youlu Hua, Yangde Li, Weirong Li, and Wei Li. 2019. "Template-assisted, Sol-gel Fabrication of Biocompatible, Hierarchically Porous Hydroxyapatite Scaffolds" Materials 12, no. 8: 1274. https://doi.org/10.3390/ma12081274