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Open AccessArticle

3D Graphene-Nitrogen Doped Carbon Nanotubes Network Modified Electrode as Sensing Materials for the Determination of Urapidil

by Yanju Wu 1, Anxing Zhou 1, Huimin Yang 1, Fei Wang 1,* and Kui Lu 2,*
1
School of Material and Chemistry Engineering, Henan University of Engineering, Zhengzhou 450007, China
2
School of Chemical Engineering and Food Science, Zhengzhou Institute of Technology, Zhengzhou 450044, China
*
Authors to whom correspondence should be addressed.
Materials 2018, 11(2), 322; https://doi.org/10.3390/ma11020322
Received: 30 January 2018 / Revised: 11 February 2018 / Accepted: 12 February 2018 / Published: 23 February 2018
(This article belongs to the Special Issue Advanced Functional Nanomaterials and Their Applications)
In this work, a three dimensional (3D) graphene-nitrogen doped carbon nanotubes (G-NCNTs) network was successfully fabricated on the surface of a glassy carbon (GC) electrode using the pulse potential method (PPM) in a graphene oxide-nitrogen doped carbon nanotubes (GO-NCNTs) dispersion. The morphological and characteristics of GO-NCNTs and G-NCNTs nanocomposites were investigated by atomic force microscopy (AFM), scanning electron microscopy (SEM), UV-vis spectroscopy, Raman spectroscopy, and electrochemical experiments. The 3DG-NCNTs network was applied as a new voltammetric material for the fabrication of an electrochemical platform for determination of urapidil. Systematic electrochemical tests demonstrate that the 3DG-NCNTs network modified GC electrode can effectively increase the response to the oxidation of urapidil. Under the optimum conditions, the electrochemical response was linear with urapidil concentrations in the range of 1.0 × 10−8~2.0 × 10−6 mol·L−1, while a low detection limit of 5.0 × 10−9 mol·L−1 was obtained for urapidil. Moreover, the proposed sensing platform exhibited good results for sensitivity, reproducibility, selectivity, and stability, which makes it very suitable for use as an ideal inexpensive and rapid analytical method applicable for complex drug matrices. View Full-Text
Keywords: 3D graphene; graphene-nitrogen doped carbon nanotubes; pulse potentiostatic method; electrochemical sensor; urapidil 3D graphene; graphene-nitrogen doped carbon nanotubes; pulse potentiostatic method; electrochemical sensor; urapidil
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MDPI and ACS Style

Wu, Y.; Zhou, A.; Yang, H.; Wang, F.; Lu, K. 3D Graphene-Nitrogen Doped Carbon Nanotubes Network Modified Electrode as Sensing Materials for the Determination of Urapidil. Materials 2018, 11, 322.

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