Haemocompatibility of Modified Nanodiamonds
AbstractThis study reports the interactions of modified nanodiamond particles in vitro with human blood. Modifications performed on the nanodiamond particles include oxygenation with a chemical method and hydrogenation upon chemical vapor deposition (CVD) plasma treatment. Such nanodiamonds were later incubated in whole human blood for different time intervals, ranging from 5 min to 5 h. The morphology of red blood cells was assessed along with spectral measurements and determination of haemolysis. The results showed that no more than 3% of cells were affected by the nanodiamonds. Specific modifications of the nanodiamonds give us the possibility to obtain nanoparticles which are biocompatible with human blood. They can form a basis for the development of nanoscale biomarkers and parts of sensing systems and devices useful in biomedical environments. View Full-Text
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Wąsowicz, M.; Ficek, M.; Wróbel, M.S.; Chakraborty, R.; Fixler, D.; Wierzba, P.; Jędrzejewska-Szczerska, M. Haemocompatibility of Modified Nanodiamonds. Materials 2017, 10, 352.
Wąsowicz M, Ficek M, Wróbel MS, Chakraborty R, Fixler D, Wierzba P, Jędrzejewska-Szczerska M. Haemocompatibility of Modified Nanodiamonds. Materials. 2017; 10(4):352.Chicago/Turabian Style
Wąsowicz, Michał; Ficek, Mateusz; Wróbel, Maciej S.; Chakraborty, Ruchira; Fixler, Dror; Wierzba, Paweł; Jędrzejewska-Szczerska, Małgorzata. 2017. "Haemocompatibility of Modified Nanodiamonds." Materials 10, no. 4: 352.
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