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Open AccessArticle

Biocompatibility and Corrosion Protection Behaviour of Hydroxyapatite Sol-Gel-Derived Coatings on Ti6Al4V Alloy

1
Centro Nacional de Investigaciones Metalúrgicas (CSIC), Madrid 28040, Spain
2
Biophysics Branch, Physics Department, Al-Azhar University, Nasr City, Cairo 11884, Egypt
3
Centro de Biomateriales, Universidad de La Habana, Havana 10600, Cuba
4
Instituto de Ciencia de Materiales de Madrid (CSIC), Madrid 28049, Spain
5
Unidad de Investigación Clínica y Biopatología Experimental, Hospital Provincial de Ávila, Unidad Asociada al CSIC, Ávila 05003, Spain
6
Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid 28029, Spain
7
Departamento de Ciencia e Ingeniería de Materiales e Ingeniería Química, Universidad Carlos III de Madrid, Leganés (Madrid) 28911, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Patrice Laquerriere
Materials 2017, 10(2), 94; https://doi.org/10.3390/ma10020094
Received: 1 December 2016 / Revised: 17 January 2017 / Accepted: 18 January 2017 / Published: 24 January 2017
(This article belongs to the Special Issue Calcium Phosphate in Biomedical Applications)
The aim of this work was to prepare hydroxyapatite coatings (HAp) by a sol-gel method on Ti6Al4V alloy and to study the bioactivity, biocompatibility and corrosion protection behaviour of these coatings in presence of simulated body fluids (SBFs). Thermogravimetric/Differential Thermal Analyses (TG/DTA) and X-ray Diffraction (XRD) have been applied to obtain information about the phase transformations, mass loss, identification of the phases developed, crystallite size and degree of crystallinity of the obtained HAp powders. Fourier Transformer Infrared Spectroscopy (FTIR) has been utilized for studying the functional groups of the prepared structures. The surface morphology of the resulting HAp coatings was studied by Scanning Electron Microscopy (SEM). The bioactivity was evaluated by soaking the HAp-coatings/Ti6Al4V system in Kokubo’s Simulated Body Fluid (SBF) applying Inductively Coupled Plasma (ICP) spectrometry. 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide (MTT) and Alamar blue cell viability assays were used to study the biocompatibility. Finally, the corrosion behaviour of HAp-coatings/Ti6Al4V system was researched by means of Electrochemical Impedance Spectroscopy (EIS). The obtained results showed that the prepared powders were nanocrystalline HAp with little deviations from that present in the human bone. All the prepared HAp coatings deposited on Ti6Al4V showed well-behaved biocompatibility, good bioactivity and corrosion protection properties. View Full-Text
Keywords: biomaterial; hydroxyapatite; calcium phosphate; sol-gel; Ti6Al4V alloy; corrosion protection; bioactivity; biocompatibility biomaterial; hydroxyapatite; calcium phosphate; sol-gel; Ti6Al4V alloy; corrosion protection; bioactivity; biocompatibility
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MDPI and ACS Style

El Hadad, A.A.; Peón, E.; García-Galván, F.R.; Barranco, V.; Parra, J.; Jiménez-Morales, A.; Galván, J.C. Biocompatibility and Corrosion Protection Behaviour of Hydroxyapatite Sol-Gel-Derived Coatings on Ti6Al4V Alloy. Materials 2017, 10, 94.

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