Austrian Red Wine Samples Reveal Enhanced Activity of the Enzyme Endothelial Nitric Oxide Synthase

O. DONATH; R. EDER; G. REZNICEK; V. M. DIRSCH

doi:10.3797/scipharm.oephg.21.SL-31

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Abstract

16 April 2009

Austrian Red Wine Samples Reveal Enhanced Activity of the Enzyme Endothelial Nitric Oxide Synthase

and

Department of Pharmacognosy, Althanstrasse 14, 1090, Vienna, Austria

Federal College and Research Institute for Viticulture and Pomology, Wiener Straße 74, 3400, Klosterneuburg, Austria

Author to whom correspondence should be addressed.

Sci. Pharm.2009, 77(6), 198;https://doi.org/10.3797/scipharm.oephg.21.SL-31

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Abstract

Red wine polyphenol extracts (RWPE) have been shown to increase nitric oxide (NO) release from EA.hy926 endothelial cells [1]. Trans-resveratrol seems to partly contribute to this effect by inducing endothelial NO-synthase (eNOS) expression [1]. Aim of this study is to identify further major active component(s) by bio-assay guided fractionation.

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