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Sci. Pharm.
Volume 77
Issue 6
10.3797/scipharm.oephg.21.SL-32
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Abstract

Virtual and Real Screening of Natural Products to Find Effective Modulators of Protein Tyrosine Phosphatase PTP1B

by
R. R. BAUMGARTNER
1,*, 3, 3, 2, 3, 2, 1, 1 and 1
1
Department of Pharmacognosy, University of Vienna, Althanstr. 14, 1090, Vienna, Austria
2
Department of Pharmacognosy, Leopold-Franzens-Universität Innsbruck, Innrain 52c, Josef-Moeller-Haus, 6020, Innsbruck, Austria
3
Department of Pharmaceutical Chemistry, Leopold-Franzens-Universität Innsbruck, Innrain 52c, Josef-Moeller-Haus, 6020, Innsbruck, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(6), 199; https://doi.org/10.3797/scipharm.oephg.21.SL-32
Received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Abstract

The protein tyrosine phosphatase 1B (PTP1B) is an important negative regulator of the insulin receptor. Elchebly M. et al showed that PTP1B knockout mice enhanced insulin sensitivity and were completely healthy and resistant to weight gain when put on a high fat diet (1). This makes PTP1B a promising target for diabetes type 2 and metabolic syndrome.

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MDPI and ACS Style

BAUMGARTNER, R.R.; STEINDL, T.M.; SCHUSTER, D.; ROLLINGER, J.M.; WOLBER, G.; STUPPNER, H.; ATANASOV, A.G.; HEISS, E.H.; DIRSCH, V.M. Virtual and Real Screening of Natural Products to Find Effective Modulators of Protein Tyrosine Phosphatase PTP1B. Sci. Pharm. 2009, 77, 199. https://doi.org/10.3797/scipharm.oephg.21.SL-32

AMA Style

BAUMGARTNER RR, STEINDL TM, SCHUSTER D, ROLLINGER JM, WOLBER G, STUPPNER H, ATANASOV AG, HEISS EH, DIRSCH VM. Virtual and Real Screening of Natural Products to Find Effective Modulators of Protein Tyrosine Phosphatase PTP1B. Scientia Pharmaceutica. 2009; 77(Short Lectures (SL)):199. https://doi.org/10.3797/scipharm.oephg.21.SL-32

Chicago/Turabian Style

BAUMGARTNER, R. R., T. M. STEINDL, D. SCHUSTER, J. M. ROLLINGER, G. WOLBER, H. STUPPNER, A. G. ATANASOV, E. H. HEISS, and V. M. DIRSCH. 2009. "Virtual and Real Screening of Natural Products to Find Effective Modulators of Protein Tyrosine Phosphatase PTP1B" Scientia Pharmaceutica 77, Short Lectures (SL): 199. https://doi.org/10.3797/scipharm.oephg.21.SL-32

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