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Pathophysiology, Volume 29, Issue 1

2022 March - 12 articles

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Articles (12)

  • Article
  • Open Access
3 Citations
3,298 Views
9 Pages

In pulmonary hypertension (PH), the development of right ventricular (RV) dilatation and RV failure are signs of accelerated progression of the disease, resulting in an increased risk of cardiac death. Even the noninvasive assessment of systolic bloo...

  • Article
  • Open Access
8 Citations
5,726 Views
16 Pages

Daytime Exposure to Blue Light Alters Cardiovascular Circadian Rhythms, Electrolyte Excretion and Melatonin Production

  • Anna A. Bryk,
  • Mikhail L. Blagonravov,
  • Vyacheslav A. Goryachev,
  • Sergey M. Chibisov,
  • Madina M. Azova and
  • Sergey P. Syatkin

Artificial light is characterized by certain features of its impact on the body in terms of its spectral distribution of power, duration of exposure and intensity. Short waves, perceived as blue light, are the strongest synchronizing agent for the ci...

  • Article
  • Open Access
8 Citations
4,004 Views
12 Pages

Predictors of Mortality Following Aortic Valve Replacement in Aortic Stenosis Patients

  • Vladimir Shvartz,
  • Maria Sokolskaya,
  • Andrey Petrosyan,
  • Artak Ispiryan,
  • Sergey Donakanyan,
  • Leo Bockeria and
  • Olga Bockeria

Background: Understanding of the risk factors for the development of adverse outcomes after aortic valve replacement is necessary to develop timely preventive measures and to improve the results of surgical treatment. Methods: We analyzed patients wi...

  • Article
  • Open Access
1 Citations
3,977 Views
14 Pages

Evaluation of Antibacterial and Antiviral Drug Effectiveness in COVID-19 Therapy: A Data-Driven Retrospective Approach

  • Rika Yulia,
  • Putri Ayu Irma Ikasanti,
  • Fauna Herawati,
  • Ruddy Hartono,
  • Puri Safitri Hanum,
  • Lestiono,
  • Dewi Ramdani,
  • Abdul Kadir Jaelani,
  • Kevin Kantono and
  • Heru Wijono

The clinical manifestations associated with COVID-19 disease is mainly due to a dysregulated host response related to the overexpression of inflammatory markers. Until recently, only remdesivir had gained FDA approval for COVID-19 hospitalized patien...

  • Article
  • Open Access
9 Citations
3,442 Views
11 Pages

Polymorphism in Adiponectin and Adiponectin Receptor Genes in Diabetes Mellitus Pathogenesis

  • Iuliana Shramko,
  • Elizaveta Ageeva,
  • Eugene Krutikov,
  • Konstantin Maliy,
  • Irina Repinskaya,
  • Iryna Fomochkina,
  • Anatolii Kubishkin,
  • Anna Gurtovaya,
  • Cyrill Tarimov and
  • Suman Shekhar

The role played by hereditary factors in the development of diabetes mellitus type 2 (DM2) has not yet been fully established. Therefore, the purpose of our study was to investigate the prevalence of adiponectin and polymorphism in its gene receptors...

  • Article
  • Open Access
7 Citations
4,726 Views
15 Pages

Mapping Research on miRNAs in Cancer: A Global Data Analysis and Bibliometric Profiling Analysis

  • Peter Shaw,
  • Kartik Lokhotiya,
  • Chellan Kumarasamy,
  • Krishnan Sunil,
  • Deepa Suresh,
  • Sameep Shetty,
  • Gothandam Kodiveri Muthukaliannan,
  • Siddhartha Baxi,
  • Ravishankar Ram Mani and
  • Rama Jayaraj
  • + 4 authors

miRNAs biomarkers are emerging as an essential part of clinical oncology. Their oncogenic and tumour suppressor properties playing a role in malignancy has generated interest in their potential for use in disease prognosis. While several studies on m...

  • Article
  • Open Access
14 Citations
3,900 Views
14 Pages

Adhesion Molecules ICAM-1 and PECAM-1 as Potential Biomarkers of Central Nervous System Damage in Women Breast Cancer Survivors

  • Maria Pospelova,
  • Varvara Krasnikova,
  • Olga Fionik,
  • Tatyana Alekseeva,
  • Konstantin Samochernykh,
  • Nataliya Ivanova,
  • Nikita Trofimov,
  • Tatyana Vavilova,
  • Elena Vasilieva and
  • Maxim Shevtsov
  • + 6 authors

Breast cancer (BC) is the most common tumor in women worldwide with high mortality rates. Surgical methods followed by radio–chemotherapy are used to treat these tumors. Such treatment can lead to various side effects, including neurological co...

  • Feature Paper
  • Article
  • Open Access
11 Citations
3,658 Views
20 Pages

Oxidative Stress and Free Radical Processes in Tumor and Non-Tumor Obstructive Jaundice: Influence of Disease Duration, Severity and Surgical Treatment on Outcomes

  • Ekaterina Vladimirovna Silina,
  • Victor Alexandrovich Stupin,
  • Igor Sergeevich Abramov,
  • Sergey Brankovich Bolevich,
  • Gouri Deshpande,
  • Raghu Ram Achar and
  • Tatiana Georgievna Sinelnikova

The aim of this study was to assess the patterns and pattern disruptions of free radical processes in patients with obstructive jaundice of various origins, and the severity of jaundice before and after decompression. Oxidative stress markers were de...

  • Article
  • Open Access
28 Citations
29,245 Views
6 Pages

New Clinical Phenotype of the Post-Covid Syndrome: Fibromyalgia and Joint Hypermobility Condition

  • Natalia Gavrilova,
  • Lidiia Soprun,
  • Maria Lukashenko,
  • Varvara Ryabkova,
  • Tamara V. Fedotkina,
  • Leonid P. Churilov and
  • Yehuda Shoenfeld

Fibromyalgia can be defined as a chronic pain condition, affecting the musculoskeletal system, etiology and pathophysiology of which is sufficiently understudied. Despite the fact that many authors consider this entity to be a manifestation of centra...

  • Article
  • Open Access
4 Citations
3,798 Views
15 Pages

Angiopoietin-Like Protein 4 and Insulin-Like Growth Factor-1 Expression in Invasive Breast Carcinoma in Young Women

  • Zaleha Kamaludin,
  • Alaa Siddig,
  • Najib Majdi Yaacob,
  • Alfred K. Lam and
  • Wan Faiziah Wan Abdul Rahman

Biomarker identification is imperative for invasive breast carcinoma, which is more aggressive and associated with higher mortality and worse prognosis in younger patients (<45 years) than in older patients (>50 years). The current study aimed...

  • Review
  • Open Access
22 Citations
5,700 Views
8 Pages

Corneal Confocal Microscopy in the Diagnosis of Small Fiber Neuropathy: Faster, Easier, and More Efficient Than Skin Biopsy?

  • Mariia V. Lukashenko,
  • Natalia Y. Gavrilova,
  • Anna V. Bregovskaya,
  • Lidiia A. Soprun,
  • Leonid P. Churilov,
  • Ioannis N. Petropoulos,
  • Rayaz A Malik and
  • Yehuda Shoenfeld

Chronic pain may affect 30–50% of the world’s population and an important cause is small fiber neuropathy (SFN). Recent research suggests that autoimmune diseases may be one of the most common causes of small nerve fiber damage. There is...

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Pathophysiology - ISSN 1873-149X