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Effect of per Capita Income on the Relationship between Periodontal Disease during Pregnancy and the Risk of Preterm Birth and Low Birth Weight Newborn. Systematic Review and Meta-Analysis

Stomatology Department, University of Valencia, 46010 València, Spain
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Int. J. Environ. Res. Public Health 2020, 17(21), 8015; https://doi.org/10.3390/ijerph17218015
Received: 9 September 2020 / Revised: 23 October 2020 / Accepted: 29 October 2020 / Published: 30 October 2020
This work analyzed the available evidence in the scientific literature about the risk of preterm birth and/or giving birth to low birth weight newborns in pregnant women with periodontal disease. A systematic search was carried out in three databases for observational cohort studies that related periodontal disease in pregnant women with the risk of preterm delivery and/or low birth weight, and that gave their results in relative risk (RR) values. Eleven articles were found, meeting the inclusion criteria. Statistically significant values were obtained regarding the risk of preterm birth in pregnant women with periodontitis (RR = 1.67 (1.17–2.38), 95% confidence interval (CI)), and low birth weight (RR = 2.53 (1.61–3.98) 95% CI). When a meta-regression was carried out to relate these results to the income level of each country, statistically significant results were also obtained; on the one hand, for preterm birth, a RR = 1.8 (1.43–2.27) 95% CI was obtained and, on the other hand, for low birth weight, RR = 2.9 (1.98–4.26) 95% CI. A statistically significant association of periodontitis, and the two childbirth complications studied was found, when studying the association between these results and the country’s per capita income level. However, more studies and clinical trials are needed in this regard to confirm the conclusions obtained. View Full-Text
Keywords: periodontal disease; premature birth; low birth weight; risk factor; income level; meta-analysis periodontal disease; premature birth; low birth weight; risk factor; income level; meta-analysis
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MDPI and ACS Style

Moliner-Sánchez, C.A.; Iranzo-Cortés, J.E.; Almerich-Silla, J.M.; Bellot-Arcís, C.; Ortolá-Siscar, J.C.; Montiel-Company, J.M.; Almerich-Torres, T. Effect of per Capita Income on the Relationship between Periodontal Disease during Pregnancy and the Risk of Preterm Birth and Low Birth Weight Newborn. Systematic Review and Meta-Analysis. Int. J. Environ. Res. Public Health 2020, 17, 8015. https://doi.org/10.3390/ijerph17218015

AMA Style

Moliner-Sánchez CA, Iranzo-Cortés JE, Almerich-Silla JM, Bellot-Arcís C, Ortolá-Siscar JC, Montiel-Company JM, Almerich-Torres T. Effect of per Capita Income on the Relationship between Periodontal Disease during Pregnancy and the Risk of Preterm Birth and Low Birth Weight Newborn. Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2020; 17(21):8015. https://doi.org/10.3390/ijerph17218015

Chicago/Turabian Style

Moliner-Sánchez, Carmen Alba, José Enrique Iranzo-Cortés, José Manuel Almerich-Silla, Carlos Bellot-Arcís, José Carmelo Ortolá-Siscar, José María Montiel-Company, and Teresa Almerich-Torres. 2020. "Effect of per Capita Income on the Relationship between Periodontal Disease during Pregnancy and the Risk of Preterm Birth and Low Birth Weight Newborn. Systematic Review and Meta-Analysis" International Journal of Environmental Research and Public Health 17, no. 21: 8015. https://doi.org/10.3390/ijerph17218015

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