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Reply published on 6 January 2016, see Int. J. Environ. Res. Public Health 2016, 13(1), 109.
Comment

Comments on Scheffler et al. Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health, 2015, 12, 12466-12474

1
Dipartimento di Medicina Clinica e Sperimentale, Università di Catania, Via Palermo 636, 95121 Catania, Italy
2
Dipartimento di Scienze Biomediche e Biotecnologiche, V.le A. Doria 6, 95125 Catania, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Paul B. Tchounwou
Int. J. Environ. Res. Public Health 2016, 13(1), 108; https://doi.org/10.3390/ijerph13010108
Received: 24 December 2015 / Accepted: 31 December 2015 / Published: 6 January 2016
There is merit in considering a simple toxicological screening method that evaluates the total cytotoxic potential of e-liquids or electronic cigarettes (ECs) aerosol emissions in one single testing. However, there is growing confusion, with several researchers endorsing their personal solution to the problem. Here, we discuss as an example the recent paper by Scheffler and colleagues, in which the authors suggest that more relevant and well differentiated cell lines from human airways could be the most suitable candidates for toxicological evaluation of ECs aerosol emissions. We advance recommendations for validated protocols and advocate for an international coordinated effort aimed at establishing consensus on methodology. View Full-Text
Keywords: vapour emission; electronic cigarette; cytotoxicity; tobacco product directive vapour emission; electronic cigarette; cytotoxicity; tobacco product directive
MDPI and ACS Style

Polosa, R.; Caruso, M.; Guarino, F. Comments on Scheffler et al. Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health, 2015, 12, 12466-12474. Int. J. Environ. Res. Public Health 2016, 13, 108. https://doi.org/10.3390/ijerph13010108

AMA Style

Polosa R, Caruso M, Guarino F. Comments on Scheffler et al. Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health, 2015, 12, 12466-12474. International Journal of Environmental Research and Public Health. 2016; 13(1):108. https://doi.org/10.3390/ijerph13010108

Chicago/Turabian Style

Polosa, Riccardo, Massimo Caruso, and Francesca Guarino. 2016. "Comments on Scheffler et al. Cytotoxic Evaluation of E-Liquid Aerosol using Different Lung Derived Cell Models. Int. J. Environ. Res. Public Health, 2015, 12, 12466-12474" International Journal of Environmental Research and Public Health 13, no. 1: 108. https://doi.org/10.3390/ijerph13010108

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