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Collagen of Extracellular Matrix from Marine Invertebrates and Its Medical Applications

1
Department of Chemical & Physical Sciences, University of Toronto, Mississauga, ON L5L 1C6, Canada
2
Center for Climate Change Research, Toronto, ON M4P 1J4, Canada
Mar. Drugs 2019, 17(2), 118; https://doi.org/10.3390/md17020118
Received: 22 December 2018 / Revised: 25 January 2019 / Accepted: 5 February 2019 / Published: 14 February 2019
(This article belongs to the Special Issue Collagen from Marine Biological Source and Medical Applications)
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Abstract

The extraction and purification of collagen are of great interest due to its biological function and medicinal applications. Although marine invertebrates are abundant in the animal kingdom, our knowledge of their extracellular matrix (ECM), which mainly contains collagen, is lacking. The functions of collagen isolated from marine invertebrates remain an untouched source of the proteinaceous component in the development of groundbreaking pharmaceuticals. This review will give an overview of currently used collagens and their future applications, as well as the methodological issues of collagens from marine invertebrates for potential drug discovery. View Full-Text
Keywords: collagen; chitin; corals; extracellular matrix; marine invertebrates; marine proteins collagen; chitin; corals; extracellular matrix; marine invertebrates; marine proteins
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Rahman, M.A. Collagen of Extracellular Matrix from Marine Invertebrates and Its Medical Applications. Mar. Drugs 2019, 17, 118.

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