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New Oxidized Zoanthamines from a Canary Islands Zoanthus sp.

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Institute of Bio-Organic Chemistry "Antonio González", Center for Biomedical Research of the Canary Islands, University of La Laguna, 38206 Tenerife, Spain
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Faculty of Bioanalysis Campus-Veracruz, Universidad Veracruzana, 91700 Veracruz, Mexico
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Department of Organic Chemistry, Faculty of Health Sciences, University of La Laguna, 38206 Tenerife, Spain
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Department of Chemical Engineering and Pharmaceutical Technology, Faculty of Health Sciences, University of La Laguna, 38206 Tenerife, Spain
*
Authors to whom correspondence should be addressed.
Mar. Drugs 2014, 12(10), 5188-5196; https://doi.org/10.3390/md12105188
Received: 1 August 2014 / Revised: 16 September 2014 / Accepted: 18 September 2014 / Published: 14 October 2014
Three new norzoanthamine-type alkaloids, named 2-hydroxy-11-ketonorzoan thamide B (1), norzoanthamide B (2) and 15-hydroxynorzoanthamine (3), were isolated from Zoanthus sp. specimens collected at the Canary Islands. Their structures were determined by interpretation of NMR and HR-ESIMS data. Relative configurations of their chiral centers were proposed on the basis of ROESY spectra and by comparison of their spectroscopic data with those of the well-known compound, norzoanthamine. View Full-Text
Keywords: Zoanthus; zoanthamine alkaloids; marine natural products Zoanthus; zoanthamine alkaloids; marine natural products
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Cen-Pacheco, F.; Martín, M.N.; Fernández, J.J.; Hernández Daranas, A. New Oxidized Zoanthamines from a Canary Islands Zoanthus sp.. Mar. Drugs 2014, 12, 5188-5196.

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