Current Issues in Molecular Biology, Volume 5, Issue 2

The relationship between gene expression profiles and cellular phenotypes is an important aspect of functional genomics. Clinical tissue specimens will play a vital role in this effort. The usefulness of tissue for molecular profiling is significantl...

Genomics today involves the study of many genes at a time in order to gain an integrated picture of the cell or organism as a whole. This review considers the architecture and evolution of bacterial genomes. The many facets of large-scale functiona...

Single nucleotide polymorphism (SNP) detection technologies are used to scan for new polymorphisms and to determine the allele(s) of a known polymorphism in target sequences. SNP detection technologies have evolved from labor intensive, time consu...