Correction: Nazarloo et al. Oxytocin, Vasopressin and Stress: A Hormetic Perspective. Curr. Issues Mol. Biol. 2025, 47, 632

Hans P. Nazarloo; Marcy A. Kingsbury; Hannah Lamont; Caitlin V. Dale; Parmida Nazarloo; John M. Davis; Eric C. Porges; Steven P. Cuffe; C. Sue Carter

doi:10.3390/cimb48030246

The authors would like to make the following correction to their published paper [1]. The change is as follows:

Reference [32,33,56,59,62–65,68,69,71,76,78,84,86,98,102,107,109,113,118,119,123,127,139,140,142,145,147,150,152–154,159,168,169,179,180,182,184–186,193–195] in the original publication is incorrectly cited and needs to be replaced with the following reference:

32.: Lee, I.H.; Cao, L.; Mostoslavsky, R.; Lombard, D.B.; Liu, J.; Bruns, N.E.; Tsokos, M.; Alt, F.W.; Finkel, T. A Role for the NAD-Dependent Deacetylase Sirt1 in the Regulation of Autophagy. Proc. Natl. Acad. Sci. USA 2008, 105, 3374–3379. https://doi.org/10.1073/pnas.0712145105.
33.: Hernández-Camacho, J.D.; García-Corzo, L.; Moreno Fernández-Ayala, D.J.; Navas, P.; López-Lluch, G. Coenzyme Q at the Hinge of Health and Metabolic Diseases. Antioxidants 2021, 10, 1785. https://doi.org/10.3390/antiox10111785.
56.: Sukhareva, E.V. The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response. Vavilovskii Zhurnal Genet. Selektsii 2021, 25, 216–223. https://doi.org/10.18699/VJ21.025.
59.: Bagosi, Z.; Megyesi, K.; Ayman, J.; Rudersdorf, H.; Ayaz, M.K.; Csabafi, K. The Role of Corticotropin-Releasing Factor (CRF) and CRF-Related Peptides in the Social Behavior of Rodents. Biomedicines 2023, 11, 2217. https://doi.org/10.3390/biomedicines11082217.
62.: Sleiman, S.F.; Henry, J.; Al-Haddad, R.; El Hayek, L.; Abou Haidar, E.; Stringer, T.; Ulja, D.; Karuppagounder, S.S.; Holson, E.B.; Ratan, R.R.; et al. Exercise Promotes the Expression of Brain-Derived Neurotrophic Factor (BDNF) through the Action of the Ketone Body β-Hydroxybutyrate. eLife 2016, 5, e15092. https://doi.org/10.7554/eLife.15092.
63.: Watts, J.A.; Arroyo, J.P. Rethinking Vasopressin: New Insights into Vasopressin Signaling and Its Implications. Kidney360 2023, 4, 1174–1180. https://doi.org/10.34067/KID.0000000000000194.
64.: Koshimizu, T.-A.; Nakamura, K.; Egashira, N.; Hiroyama, M.; Nonoguchi, H.; Tanoue, A. Vasopressin V1a and V1b Receptors: From Molecules to Physiological Systems. Physiol. Rev. 2012, 92, 1813–1864. https://doi.org/10.1152/physrev.00035.2011.
65.: Uzar, M.; Dmitrzak-Węglarz, M.; Słopień, A. The Role of Oxytocin and Vasopressin in People with Borderline Personality Disorder: A Closer Look at Adolescents. Int. J. Mol. Sci. 2024, 25, 12046. https://doi.org/10.3390/ijms252212046.
68.: Wan, Y.; Liu, J.; Mai, Y.; Hong, Y.; Jia, Z.; Tian, G.; Liu, Y.; Liang, H.; Liu, J. Current Advances and Future Trends of Hormesis in Disease. NPJ Aging 2024, 10, 26. https://doi.org/10.1038/s41514-024-00155-3.
69.: Guan, G.; Chen, Y.; Dong, Y. Unraveling the AMPK–SIRT1–FOXO Pathway: The In-Depth Analysis and Breakthrough Prospects of Oxidative Stress-Induced Diseases. Antioxidants 2025, 14, 70. https://doi.org/10.3390/antiox14010070.
71.: Perrone, P.; D’Angelo, S. Hormesis and Health: Molecular Mechanisms and the Key Role of Polyphenols. Food Chem. Adv. 2025, 7, 101030. https://doi.org/10.1016/j.focha.2025.101030.
76.: Wang, P.; Yang, H.-P.; Tian, S.; Wang, L.; Wang, S.C.; Zhang, F.; Wang, Y.-F. Oxytocin-Secreting System: A Major Part of the Neuroendocrine Center Regulating Immunologic Activity. J. Neuroimmunol. 2015, 289, 152–161. https://doi.org/10.1016/j.jneuroim.2015.11.001.
78.: Ma, Q. Role of Nrf2 in Oxidative Stress and Toxicity. Annu. Rev. Pharmacol. Toxicol. 2013, 53, 401–426. https://doi.org/10.1146/annurev-pharmtox-011112-140320.
84.: Meyer-Lindenberg, A.; Domes, G.; Kirsch, P.; Heinrichs, M. Oxytocin and Vasopressin in the Human Brain: Social Neuropeptides for Translational Medicine. Nat. Rev. Neurosci. 2011, 12, 524–538. https://doi.org/10.1038/nrn3044.
86.: Aguilera, G.; Subburaju, S.; Young, S.; Chen, J. The Parvocellular Vasopressinergic System and Responsiveness of the Hypothalamic–Pituitary–Adrenal Axis during Chronic Stress. Prog. Brain Res. 2008, 170, 29–39. https://doi.org/10.1016/S0079-6123(08)00403-2.
98.: Theodosis, D.T.; Poulain, D.A.; Oliet, S.H.R. Activity-Dependent Structural and Functional Plasticity of Astrocyte–Neuron Interactions. Physiol. Rev. 2008, 88, 983–1008. https://doi.org/10.1152/physrev.00036.2007.
102.: Aguilera, G.; Rabadan-Diehl, C. Vasopressinergic Regulation of the Hypothalamic–Pituitary–Adrenal Axis: Implications for Stress Adaptation. Regul. Pept. 2000, 96, 23–29. https://doi.org/10.1016/S0167-0115(00)00196-8.
107.: Russo, S.J.; Murrough, J.W.; Han, M.-H.; Charney, D.S.; Nestler, E.J. Neurobiology of Resilience. Nat. Neurosci. 2012, 15, 1475–1484. https://doi.org/10.1038/nn.3234.
109.: Balmus, I.M.; Ciobica, A.; Stoica, B.; Lefter, R.; Cojocaru, S.; Reznikov, A.G. Effects of Oxytocin Administration on Oxidative Markers in the Temporal Lobe of Aged Rats. Neurophysiology 2019, 51, 18–24. https://doi.org/10.1007/s11062-019-09785-w.
113.: Griebel, G.; Simiand, J.; Serradeil-Le Gal, C.; Wagnon, J.; Pascal, M.; Scatton, B.; Maffrand, J.-P.; Soubrie, P. Anxiolytic- and Antidepressant-Like Effects of the Non-Peptide Vasopressin V1b Receptor Antagonist, SSR149415, Suggest an Innovative Approach for the Treatment of Stress-Related Disorders. Proc. Natl. Acad. Sci. USA 2002, 99, 6370–6375. https://doi.org/10.1073/pnas.092012099.
118.: Ulrich-Lai, Y.M.; Herman, J.P. Neural Regulation of Endocrine and Autonomic Stress Responses. Nat. Rev. Neurosci. 2009, 10, 397–409. https://doi.org/10.1038/nrn2647.
119.: Mullur, R.; Liu, Y.-Y.; Brent, G.A. Thyroid Hormone Regulation of Metabolism. Physiol. Rev. 2014, 94, 355–382. https://doi.org/10.1152/physrev.00030.2013.
123.: McClelland, S.; Korosi, A.; Cope, J.; Ivy, A.; Baram, T.Z. Emerging Roles of Epigenetic Mechanisms in the Enduring Effects of Early-Life Stress and Experience on Learning and Memory. Neurobiol. Learn. Mem. 2011, 96, 79–88. https://doi.org/10.1016/j.nlm.2011.02.008.
127.: Myers, B.; McKlveen, J.M.; Herman, J.P. Neural Regulation of the Stress Response: The Many Faces of Feedback. Cell. Mol. Neurobiol. 2012, 32, 683–694. https://doi.org/10.1007/s10571-012-9801-y.
139.: Flaherty, S.E.; Bezy, O.; Zheng, W.; Yan, D.; Li, X.; Jagarlapudi, S.; Albuquerque, B.; Esquejo, R.M.; Peloquin, M.; Semache, M.; et al. Chronic UCN2 Treatment Desensitizes CRHR2 and Improves Insulin Sensitivity. Nat. Commun. 2023, 14, 3953. https://doi.org/10.1038/s41467-023-39597-w.
140.: Dumitras, A.G.; Piccoli, G.; Tellkamp, F.; Keufgens, L.; Baraldo, M.; Zorzato, S.; Cussonneau, L.; Nogara, L.; Krüger, M.; Blaauw, B. Neural Stimulation Suppresses mTORC1-Mediated Protein Synthesis in Skeletal Muscle. Sci. Adv. 2025, 11, eadt4955. https://doi.org/10.1126/sciadv.adt4955.
142.: Sipos, E.; Török, B.; Barna, I.; Engelmann, M.; Zelena, D. Vasopressin and Post-Traumatic Stress Disorder. Stress 2020, 23, 732–745. https://doi.org/10.1080/10253890.2020.1826430.
145.: Heinrichs, M.; Baumgartner, T.; Kirschbaum, C.; Ehlert, U. Social Support and Oxytocin Interact to Suppress Cortisol and Subjective Responses to Psychosocial Stress. Biol. Psychiatry 2003, 54, 1389–1398. https://doi.org/10.1016/S0006-3223(03)00465-7.
147.: Stoop, R. Neuromodulation by Oxytocin and Vasopressin. Neuron 2012, 76, 142–159. https://doi.org/10.1016/j.neuron.2012.09.025.
150.: Inoue, T.; Yamakage, H.; Tanaka, M.; Kusakabe, T.; Shimatsu, A.; Satoh-Asahara, N. Oxytocin Suppresses Inflammatory Responses Induced by Lipopolysaccharide through Inhibition of the eIF-2α–ATF4 Pathway in Mouse Microglia. Cells 2019, 8, 527. https://doi.org/10.3390/cells8060527.
152.: Xu, S.; Qin, B.; Shi, A.; Zhao, J.; Guo, X.; Dong, L. Oxytocin Inhibited Stress-Induced Visceral Hypersensitivity, Enteric Glial Cells Activation, and Release of Proinflammatory Cytokines in Maternal Separated Rats. Eur. J. Pharmacol. 2018, 818, 578–584. https://doi.org/10.1016/j.ejphar.2017.11.018.
153.: Sripada, C.S.; Phan, K.L.; Labuschagne, I.; Welsh, R.; Nathan, P.J.; Wood, A.G. Oxytocin Enhances Resting-State Connectivity between Amygdala and Medial Frontal Cortex. Int. J. Neuropsychopharmacol. 2013, 16, 255–260. https://doi.org/10.1017/S1461145712000533.
154.: Janeček, M.; Dabrowska, J. Oxytocin Facilitates Adaptive Fear and Attenuates Anxiety Responses in Animal Models and Human Studies—Potential Interaction with the Corticotropin-Releasing Factor (CRF) System in the Bed Nucleus of the Stria Terminalis (BNST). Cell Tissue Res. 2019, 375, 143–172. https://doi.org/10.1007/s00441-018-2889-8.
159.: Kanes, S.J.; Dennie, L.; Perera, P. Targeting the Arginine Vasopressin V1b Receptor System and Stress Response in Depression and Other Neuropsychiatric Disorders. Neuropsychiatr. Dis. Treat. 2023, 19, 811–828. https://doi.org/10.2147/NDT.S402831.
168.: Aguilera, G. Regulation of Pituitary ACTH Secretion during Chronic Stress. Front. Neuroendocrinol. 1994, 15, 321–350. https://doi.org/10.1006/frne.1994.1013.
169.: Russell, G.M.; Kalafatakis, K.; Lightman, S.L. The Importance of Biological Oscillators for Hypothalamic–Pituitary–Adrenal Activity and Tissue Glucocorticoid Response: Coordinating Stress and Neurobehavioural Adaptation. J. Neuroendocrinol. 2015, 27, 378–388. https://doi.org/10.1111/jne.12247.
179.: Lightman, S.L.; Conway-Campbell, B.L. The Crucial Role of Pulsatile Activity of the HPA Axis for Continuous Dynamic Equilibration. Nat. Rev. Neurosci. 2010, 11, 710–718. https://doi.org/10.1038/nrn2914.
180.: Dagnino-Subiabre, A. Resilience to Stress and Social Touch. Curr. Opin. Behav. Sci. 2021, 43, 75–79. https://doi.org/10.1016/j.cobeha.2021.08.011.
182.: Quintana, D.S.; Kemp, A.H.; Alvares, G.A.; Guastella, A.J. A Role for Autonomic Cardiac Control in the Effects of Oxytocin on Social Behavior and Psychiatric Illness. Front. Neurosci. 2013, 7, 48. https://doi.org/10.3389/fnins.2013.00048.
184.: Holsboer, F.; Ising, M. Precision Psychiatry Approach to Treat Depression and Anxiety Targeting the Stress Hormone System—V1b Antagonists as a Case in Point. Pharmacopsychiatry 2024, 57, 263–274. https://doi.org/10.1055/a-2372-3549.
185.: Hu, H.; Zarate, C.A., Jr.; Verbalis, J. Arginine Vasopressin in Mood Disorders: A Potential Biomarker of Disease Pathology and a Target for Pharmacologic Intervention. Psychiatry Clin. Neurosci. 2024, 78, 495–506. https://doi.org/10.1111/pcn.13703.
186.: Schoormans, D.; Kop, W.J.; Kunst, L.E.; Riem, M.M.E. Oxytocin Effects on Resting-State Heart Rate Variability in Women: The Role of Childhood Rearing Experiences. Compr. Psychoneuroendocrinol. 2020, 3, 100007. https://doi.org/10.1016/j.cpnec.2020.100007.
193.: Forcina, L.; Franceschi, C.; Musarò, A. The Hormetic and Hermetic Role of IL-6. Ageing Res. Rev. 2022, 80, 101697. https://doi.org/10.1016/j.arr.2022.101697.
194.: Johnson, J.D.; Barnard, D.F.; Kulp, A.C.; Mehta, D.M. Neuroendocrine Regulation of Brain Cytokines After Psychological Stress. J. Endocr. Soc. 2019, 3, 1302–1320. https://doi.org/10.1210/js.2019-00053.
195.: Zhang, B.; Chang, J.Y.; Lee, M.H.; Ju, S.-H.; Yi, H.-S.; Shong, M. Mitochondrial Stress and Mitokines: Therapeutic Perspectives for the Treatment of Metabolic Diseases. Diabetes Metab. J. 2024, 48, 1–18. https://doi.org/10.4093/dmj.2023.0115.

The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Reference

Nazarloo, H.P.; Kingsbury, M.A.; Lamont, H.; Dale, C.V.; Nazarloo, P.; Davis, J.M.; Porges, E.C.; Cuffe, S.P.; Carter, C.S. Oxytocin, Vasopressin and Stress: A Hormetic Perspective. Curr. Issues Mol. Biol. 2025, 47, 632. [Google Scholar] [CrossRef] [PubMed]

Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.

Article Metrics

Citations

Article Access Statistics

Journal Statistics

Multiple requests from the same IP address are counted as one view.