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Open AccessArticle

Functionalized Silver Nano-Sensor for Colorimetric Detection of Hg2+ Ions: Facile Synthesis and Docking Studies

1
Chemistry Group, Manipal Centre for Natural Sciences, Manipal Academy of Higher Education, Manipal (MAHE), Udupi 576 104, Karnataka, India
2
Faculty of Life Sciences, Division of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research (JSSAHER), Mysuru 570 015, Karnataka, India
*
Authors to whom correspondence should be addressed.
Sensors 2018, 18(8), 2698; https://doi.org/10.3390/s18082698
Received: 13 June 2018 / Revised: 23 July 2018 / Accepted: 24 July 2018 / Published: 16 August 2018
(This article belongs to the Special Issue Colorimetric Nanosensors)
In the present study, we describe the facile synthesis of silver nanoparticles (AgNPs) and their nanostructures functionalized with 2-aminopyrimidine-4,6-diol (APD-AgNPs) for Hg2+ ion detection. The promising colorimetric response of APD-AgNPs to detect Hg2+ ions was visible with naked eyes and spectroscopic changes were examined by using a UV-Visible spectrophotometer. The aggregation of APD-AgNPs upon addition of Hg2+ ions was due to the chelation effect of the functionalized nanostructures and results in a color change from pale brown to deep yellow color. The probing sensitivity was observed within five minutes with a detection limit of about 0.35 µM/L. The TEM images of APD-AgNPs showed polydispersed morphologies with hexagonal, heptagonal and spherical nanostructures with an average size between 10 to 40 nm. Furthermore, the sensing behavior of APD-AgNPs towards Hg2+ ions detection was investigated using docking and interaction studies. View Full-Text
Keywords: silver nanoparticles; Hg2+ detection; TEM analysis; docking studies silver nanoparticles; Hg2+ detection; TEM analysis; docking studies
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MDPI and ACS Style

Shiva Prasad, K.; Shruthi, G.; Shivamallu, C. Functionalized Silver Nano-Sensor for Colorimetric Detection of Hg2+ Ions: Facile Synthesis and Docking Studies. Sensors 2018, 18, 2698.

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