Next Article in Journal
Near-Space TOPSAR Large-Scene Full-Aperture Imaging Scheme Based on Two-Step Processing
Previous Article in Journal
High-Accuracy Self-Calibration for Smart, Optical Orbiting Payloads Integrated with Attitude and Position Determination
Previous Article in Special Issue
Design, Fabrication, Simulation and Characterization of a Novel Dual-Sided Microelectrode Array for Deep Brain Recording and Stimulation
Article Menu

Export Article

Open AccessReview
Sensors 2016, 16(8), 1175;

Microfluidic Surface Plasmon Resonance Sensors: From Principles to Point-of-Care Applications

Department of Mechanical Engineering, National Taiwan University, Taipei 10617, Taiwan
Author to whom correspondence should be addressed.
Academic Editors: Zhiping Wang and Charles Chun Yang
Received: 31 May 2016 / Revised: 18 July 2016 / Accepted: 21 July 2016 / Published: 27 July 2016
(This article belongs to the Special Issue Micro/Nano Fluidic Devices and Bio-MEMS)
Full-Text   |   PDF [2841 KB, uploaded 27 July 2016]   |  


Surface plasmon resonance (SPR) is a label-free, highly-sensitive, and real-time sensing technique. Conventional SPR sensors, which involve a planar thin gold film, have been widely exploited in biosensing; various miniaturized formats have been devised for portability purposes. Another type of SPR sensor which utilizes localized SPR (LSPR), is based on metal nanostructures with surface plasmon modes at the structural interface. The resonance condition is sensitive to the refractive index change of the local medium. The principles of these two types of SPR sensors are reviewed and their integration with microfluidic platforms is described. Further applications of microfluidic SPR sensors to point-of-care (POC) diagnostics are discussed. View Full-Text
Keywords: surface plasmon resonance (SPR); microfluidics; immunosensing surface plasmon resonance (SPR); microfluidics; immunosensing

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Wang, D.-S.; Fan, S.-K. Microfluidic Surface Plasmon Resonance Sensors: From Principles to Point-of-Care Applications. Sensors 2016, 16, 1175.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top