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School of Chemistry, National University of Ireland Galway, University Road, H91 TK33 Galway, Ireland
Department of Pharmacy, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames KT1 2EE, UK
Author to whom correspondence should be addressed.
Molbank 2020, 2020(2), M1129;
Received: 7 April 2020 / Revised: 24 April 2020 / Accepted: 29 April 2020 / Published: 1 May 2020
(This article belongs to the Special Issue Heterocycle Reactions)
Selectfluor (1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)) substitutes the TEMPO free radical with fluorine on 4,7-dimethoxy-1-methyl-2-{[(2,2,6,6-tetramethylpiperidin-1-yl)oxy]methyl}-1H-benzimidazole to give the title compound in a 77% yield. A mechanism is proposed for the formation of this novel methylene fluoride. View Full-Text
Keywords: fluorine; nitrogen heterocycles; nitroxide; radicals; Selectfluor; TEMPO fluorine; nitrogen heterocycles; nitroxide; radicals; Selectfluor; TEMPO
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MDPI and ACS Style

Kielty, P.; Farràs, P.; Smith, D.A.; Aldabbagh, F. 2-(Fluoromethyl)-4,7-dimethoxy-1-methyl-1H-benzimidazole. Molbank 2020, 2020, M1129.

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