5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
Abstract
:1. Introduction
2. Results and Discussion
Supplementary Materials
Supplementary File 1Supplementary File 2Supplementary File 3Supplementary File 4Acknowledgments
Author Contributions
Conflicts of Interest
References
- Dömling, A.; Wang, W.; Wang, K. Chemistry and biology of multicomponent reactions. Chem. Rev. 2012, 112, 3083–3135. [Google Scholar] [CrossRef] [PubMed]
- Ruijter, E.; Scheffelaar, R.; Orru, R.V.A. Multicomponent reaction design in the quest for molecular complexity and diversity. Angew. Chem. Int. Ed. 2011, 50, 6234–6246. [Google Scholar] [CrossRef] [PubMed]
- Van der Heijden, G.; Ruijter, E.; Orru, R.V.A. Efficiency, diversity, and complexity with multicomponent reactions. Synlett 2013, 24, 666–685. [Google Scholar]
- Chebanov, V.A.; Desenko, S.M. Multicomponent heterocyclization reactions with controlled selectivity (review). Chem. Heterocycl. Compd. 2012, 48, 566–583. [Google Scholar] [CrossRef]
- Gorobets, N.Y.; Sedash, Y.V.; Ostras, K.S.; Zaremba, O.V.; Shishkina, S.V.; Baumer, V.N.; Shishkin, O.V.; Kovalenko, S.M.; Desenko, S.M.; van der Eycken, E.V. Unexpected alternative direction of a Biginelli-like multicomponent reaction with 3-amino-1,2,4-triazole as the urea component. Tetrahedron Lett. 2010, 51, 2095–2098. [Google Scholar] [CrossRef]
- Svetlik, J.; Kettmann, V. The chameleon-like behaviour of 3-amino-1,2,4-triazole in the Biginelli reaction: Unexpected formation of a novel spiroheterocyclic system. Tetrahedron Lett. 2011, 52, 1062–1066. [Google Scholar] [CrossRef]
- Sedash, Y.V.; Gorobets, N.Y.; Chebanov, V.A.; Konovalova, I.S.; Shishkin, O.V.; Desenko, S.M. Dotting the i’S in three-component Biginelli-like condensations using 3-amino-1,2,4-triazole as a 1,3-binucleophile. RSC Adv. 2012, 2, 6719–6728. [Google Scholar] [CrossRef]
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Kondratiuk, M.; Gorobets, N.Y.; Sedash, Y.V.; Gümüş, M.K.; Desenko, S.M. 5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol. Molbank 2016, 2016, M898. https://doi.org/10.3390/M898
Kondratiuk M, Gorobets NY, Sedash YV, Gümüş MK, Desenko SM. 5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol. Molbank. 2016; 2016(2):M898. https://doi.org/10.3390/M898
Chicago/Turabian StyleKondratiuk, Michael, Nikolay Yu. Gorobets, Yuriy V. Sedash, Mustafa K. Gümüş, and Sergey M. Desenko. 2016. "5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol" Molbank 2016, no. 2: M898. https://doi.org/10.3390/M898
APA StyleKondratiuk, M., Gorobets, N. Y., Sedash, Y. V., Gümüş, M. K., & Desenko, S. M. (2016). 5-(5-Bromo-2-hydroxy-3-methoxyphenyl)-7-methyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol. Molbank, 2016(2), M898. https://doi.org/10.3390/M898