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23 January 2026

Insights on Stereoselective Residue and Degradation of Spirotetramat Enantiomers on Tubifex of the Qinghai Plateau

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1
Academy of Agriculture and Forestry Sciences, Qinghai University, Xining 810016, China
2
Key Laboratory of Qinghai-Tibetan Plateau Biotechnology (Qinghai University), Xining 810016, China
3
Scientific Observing and Experimental Station of Crop Pest in Xining, Ministry of Agriculture, Xining 810016, China
4
Key Laboratory of Agricultural Integrated Pest Management of Qinghai Province, Xining 810016, China
This article belongs to the Special Issue Molecular Strategies for the Discovery, Optimization, and Efficient Use of Green Pesticides

Abstract

This study established an HPLC-MS/MS method to quantify the enantiomers of spirotetramat in tubifex. To assess the accuracy and precision of the approach, recovery tests were conducted for insecticide. For all enantiomers, the limits of detection were 0.003 mg/kg. The quantization limits were 0.01 mg/kg. Spirotetramat enantiomers recovery rates in tubifex were found to be between 81 and 114%, with relative standard deviations being less than 7%. The half-lives of spirotetramat enantiomers in tubifex were 3.81–10.58 d, respectively. The 22.4% spirotetramat suspension was sprayed on tubifex three times at a low dosage (high dosage advised). After 14 days after harvesting, the terminal residues of spirotetramat enantiomers in the tubifex were less than 0.03 mg/kg. The findings offer a quantitative foundation for setting China’s maximum residue limits as well as a recommendation for the safe and responsible usage of spirotetramat enantiomers in tubifex.

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