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Retraction

RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554

1
Institut für Anorganische und Analytische Chemie, Westfälische Wilhelms-Universität Münster, Corrensstraße 30, 48149 Münster, Germany
2
NRW Graduate School of Chemistry, Westfälische Wilhelms-Universität Münster, Corrensstraße 30, 48149 Münster, Germany
*
Author to whom correspondence should be addressed.
Int. J. Mol. Sci. 2025, 26(11), 5409; https://doi.org/10.3390/ijms26115409
Submission received: 21 May 2025 / Accepted: 21 May 2025 / Published: 5 June 2025
(This article belongs to the Section Biochemistry)
The Journal retracts the article “6-Pyrazolylpurine as an artificial nucleobase for metal-mediated base pairing in DNA duplexes” [1] cited above.
Following publication, the authors contacted the Editorial Office to raise concerns relating to identity of the oligonucleotides used in that publication [1], as a result of an inadvertent error. In particular, subsequent attempts to reproduce their synthesis indicated that the artificial nucleobase 6-pyrazolylpurine had decomposed upon or after incorporation into the oligonucleotides, i.e., prior to its study in the DNA duplexes. In the meantime, correct results and several reference measurements have been reported elsewhere [2].
Adhering to our standard procedure, an investigation was conducted by the Editorial Office and Editorial Board that confirmed weaknesses in the experimental evidence provided in the article. Given the impact of this issue on the validity of results, the Editorial Board and the authors have determined that the overall findings could not be relied upon and decided to retract this publication [1], as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30).
This retraction was approved by the Editor-in-Chief of the journal IJMS.
The authors agreed to this retraction.

References

  1. Léon, J.C.; Sinha, I.; Müller, J. RETRACTED: 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554. [Google Scholar] [CrossRef] [PubMed]
  2. Escher, D.; Schäfer, T.; Hebenbrock, M.; Müller, J. 6-Pyrazolylpurine and its deaza derivatives as nucleobases for silver(I)-mediated base pairing with pyrimidines. J. Biol. Inorg. Chem. 2023, 28, 791–803. [Google Scholar] [CrossRef] [PubMed]
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Share and Cite

MDPI and ACS Style

Léon, J.C.; Sinha, I.; Müller, J. RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554. Int. J. Mol. Sci. 2025, 26, 5409. https://doi.org/10.3390/ijms26115409

AMA Style

Léon JC, Sinha I, Müller J. RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554. International Journal of Molecular Sciences. 2025; 26(11):5409. https://doi.org/10.3390/ijms26115409

Chicago/Turabian Style

Léon, J. Christian, Indranil Sinha, and Jens Müller. 2025. "RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554" International Journal of Molecular Sciences 26, no. 11: 5409. https://doi.org/10.3390/ijms26115409

APA Style

Léon, J. C., Sinha, I., & Müller, J. (2025). RETRACTED: Léon et al. 6-Pyrazolylpurine as an Artificial Nucleobase for Metal-Mediated Base Pairing in DNA Duplexes. Int. J. Mol. Sci. 2016, 17, 554. International Journal of Molecular Sciences, 26(11), 5409. https://doi.org/10.3390/ijms26115409

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