Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells
Abstract
1. Introduction
2. Astrocyte Development and Heterogeneity
3. Astrocyte Function
3.1. Water and Ion Homeostasis
3.2. Calcium Signaling
3.3. Synaptic Development
3.4. Synaptic Function and Plasticity
4. Human-Specific Characteristics of Astrocytes
5. Generation of hiPSC-Astrocytes
6. Modeling Astrocytes in Neurodevelopmental Disorders
6.1. Down Syndrome
6.2. Rett Syndrome
6.3. Schizophrenia
7. Challenges and Opportunities
8. Conclusions
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Ren, B.; Dunaevsky, A. Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells. Int. J. Mol. Sci. 2021, 22, 1692. https://doi.org/10.3390/ijms22041692
Ren B, Dunaevsky A. Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells. International Journal of Molecular Sciences. 2021; 22(4):1692. https://doi.org/10.3390/ijms22041692
Chicago/Turabian StyleRen, Baiyan, and Anna Dunaevsky. 2021. "Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells" International Journal of Molecular Sciences 22, no. 4: 1692. https://doi.org/10.3390/ijms22041692
APA StyleRen, B., & Dunaevsky, A. (2021). Modeling Neurodevelopmental and Neuropsychiatric Diseases with Astrocytes Derived from Human-Induced Pluripotent Stem Cells. International Journal of Molecular Sciences, 22(4), 1692. https://doi.org/10.3390/ijms22041692