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Molecules 2003, 8(7), 536-540;

Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives

Department of Organic Chemistry, Slovak University of Technology, Radlinského Street 9, Slovakia
Author to whom correspondence should be addressed.
Received: 13 June 2003 / Accepted: 26 June 2003 / Published: 15 July 2003
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We present 1-pentafluorophenyl-1H-pyrrole and some of its electrophilic substitution reactions: formylation and acetylations. The 2-substituted products formed in these reactions are selectively and in high yield converted into 3-substituted products by treatment with trifluoromethanesulfonic acid. A general synthesis of 3-acylpyrroles was developed by the trifluoromethanesulfonic acid-mediated rearrangement of the corresponding 2-acylpyrroles. View Full-Text
Keywords: Conducting materials; supramolecular synthons; pyrroles Conducting materials; supramolecular synthons; pyrroles

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Hrnčariková, K.; Végh, D. Synthesis and Reactivity of New 1-Pentafluorophenyl-1Hpyrrole Derivatives. Molecules 2003, 8, 536-540.

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