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Molecules 2001, 6(9), 716-720;

Synthesis of Camalexin

Department of Organic Chemistry, Faculty of Natural Sciences, P.J. Šafárik University, Moyzesova 11, 041 67 Košice, Slovak Republic
Institute of chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, 842 38 Bratislava, Slovak Republic
Author to whom correspondence should be addressed.
Received: 6 April 2001 / Revised: 13 August 2001 / Accepted: 14 August 2001 / Published: 31 August 2001
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In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl Lcysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, 1H NMR, 13C NMR and mass spectroscopy. View Full-Text
Keywords: Camalexin; phytoalexins; indoles Camalexin; phytoalexins; indoles

Figure 1

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Dzurilla, M.; Kutschy, P.; Zaletova, J.; Ruzinsky, M.; Kovacik, V. Synthesis of Camalexin. Molecules 2001, 6, 716-720.

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