Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol
Abstract
:1. Introduction
2. Results
3. Materials and Methods
3.1. Specimen Preparation and Initial Demineralization
3.2. Secondary Demineralization
3.3. Transverse Microradiographic Analysis
3.4. Statistical Analysis
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
TMR | Transverse microradiography |
L | Lesion depth |
ΔL | Changes in lesion depth |
SZmax | Degree of surface layer mineralization |
ΔSZmax | Changes in surface layer mineralization |
ΔZ | Mineral content |
ΔΔZ | Changes in mineral content |
References
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Group | Fluoride (ppm) | Theo-bromine (ppm) | n | Mineral Loss – ΔZ (vol.%) | Lesion Depth – L (µm) | Surface Zone Mineralization –SZmax (vol.%) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre | Post | ΔΔZ | p-Value for Paired t-Test 1 | Pre | Post | ΔL | p-Value for Paired t-Test 1 | Pre | Post | ΔSZmax | p-Value for Paired t-Test 1 | ||||
A | 0 | 50 | 11 | 1607.3 (253.6)A/a | 1995.5 (331.6) | −388.2 (306.1)B/a | 0.002 | 65.4 (8.5)A/a | 72.3 (9.9) | −6.9 (6.7)B/a | 0.006 | 63.2 (4.4)A/a | 63.8 (4.2) | −0.6 (4.3)A/a | 0.677 |
B | 0 | 200 | 14 | 1667.9 (280.2)A/a | 2236.4 (477.3) | −568.6 (343.3)B/a | < 0.001 | 66.7 (9.3)A/a | 80.2 (13.7) | −13.5 (7.8)B/a,b | < 0.001 | 64.3 (5.6)A/a | 64.0 (6.9) | 0.3 (6.4)A/a | 0.857 |
C | 1 | 50 | 15 | 1674.0 (318.5)A/a | 2045.3 (244.6) | −371.3 (376.7)B/a | < 0.001 | 66.1 (8.8)A/a | 85.4 (8.1) | −19.3 (9.7)B/b | < 0.001 | 64.9 (4.2)A/a | 66.9 (4.5) | −2.0 (4.5)A/a | 0.114 |
D | 1 | 200 | 14 | 1506.4 (435.8)A/a | 1875.7 (391.4) | −369.3 (271.1)B/a | < 0.001 | 63.7 (13.5)A/a | 81.1 (13.0) | −17.3 (7.3)B/b | < 0.001 | 63.9 (6.9)A/a | 65.5 (5.6) | −1.7 (5.1)A/a | 0.242 |
p-value for ANOVA 2 | 0.516 | - | 0.319 | - | 0.882 | - | 0.002 | - | 0.875 | - | 0.629 | - |
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Nassar, H.M.; Lippert, F. Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol. Molecules 2021, 26, 300. https://doi.org/10.3390/molecules26020300
Nassar HM, Lippert F. Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol. Molecules. 2021; 26(2):300. https://doi.org/10.3390/molecules26020300
Chicago/Turabian StyleNassar, Hani M., and Frank Lippert. 2021. "Artificial Caries Lesion Characteristics after Secondary Demineralization with Theobromine-Containing Protocol" Molecules 26, no. 2: 300. https://doi.org/10.3390/molecules26020300