Next Article in Journal
Biosynthesized ZnO Nanoparticles Using Albizia lebbeck Extract Induced Biochemical and Morphological Alterations in Wistar Rats
Previous Article in Journal
Actinidia arguta Leaf as a Donor of Potentially Healthful Bioactive Compounds: Implications of Cultivar, Time of Sampling and Soil N Level
Previous Article in Special Issue
Targeting Multiple Signal Transduction Pathways of SARS-CoV-2: Approaches to COVID-19 Therapeutic Candidates
Review

A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov

1
Department of Forestry Science and Biodiversity, Faculty of Forestry and Environment, Universiti Putra Malaysia, Serdang 43400, Malaysia
2
Laboratory of Bioresource Management, Institute of Tropical Forestry and Forest Products (INTROP), Universiti Putra Malaysia, Serdang 43400, Malaysia
3
Educational and Scientific Center “Institute of Biology and Medicine”, Department of Plant Biology, Taras Shevchenko National University of Kyiv, Volodymyrska 60, 01033 Kyiv, Ukraine
4
Department of Plant Physiology, Slovak University of Agriculture Nitra, A. Hlinku 2, 94976 Nitra, Slovakia
5
Department of Microbiology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah 6718773654, Iran
6
Fertility and Infertility Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah 6718773654, Iran
7
Biological and Health Sciences Centre, Laboratory of Botanical Studies, Department of Biology, Federal University of Maranhão, São Luís 65080-805, MA, Brazil
8
Department of Physics, Central University of Punjab, Bathinda 151401, India
9
Department of Biotechnology, Federal Scientific Center of the East Asia Terrestrial Biodiversity (Institute of Biology and Soil Science), Far Eastern Branch of the Russian Academy of Sciences, 159 Stoletija Str., 690022 Vladivostok, Russia
10
Leicester School of Pharmacy, De Montfort University, The Gateway, Leicester LE1 9BH, UK
11
Health Sciences Graduate Program, Biological & Health Sciences Centre, Federal University of Maranhão, São Luís 65080-805, MA, Brazil
12
Laboratoire de Biologie des Ligneux et des Grandes Cultures (LBLGC), University of Orléans, 1 Rue de Chartres-BP 6759, 45067 Orleans, France
*
Authors to whom correspondence should be addressed.
Academic Editors: Eduardo Sobarzo-Sánchez and Esra Küpeli Akkol
Molecules 2021, 26(13), 3868; https://doi.org/10.3390/molecules26133868
Received: 5 March 2021 / Revised: 2 June 2021 / Accepted: 3 June 2021 / Published: 24 June 2021
(This article belongs to the Special Issue Natural Products for COVID-19: Prevention and Treatment)
The COVID-19 pandemic, as well as the more general global increase in viral diseases, has led researchers to look to the plant kingdom as a potential source for antiviral compounds. Since ancient times, herbal medicines have been extensively applied in the treatment and prevention of various infectious diseases in different traditional systems. The purpose of this review is to highlight the potential antiviral activity of plant compounds as effective and reliable agents against viral infections, especially by viruses from the coronavirus group. Various antiviral mechanisms shown by crude plant extracts and plant-derived bioactive compounds are discussed. The understanding of the action mechanisms of complex plant extract and isolated plant-derived compounds will help pave the way towards the combat of this life-threatening disease. Further, molecular docking studies, in silico analyses of extracted compounds, and future prospects are included. The in vitro production of antiviral chemical compounds from plants using molecular pharming is also considered. Notably, hairy root cultures represent a promising and sustainable way to obtain a range of biologically active compounds that may be applied in the development of novel antiviral agents. View Full-Text
Keywords: bioactive compounds; coronavirus; hairy roots; herbal medicines; molecular farming; plant extracts; respiratory diseases bioactive compounds; coronavirus; hairy roots; herbal medicines; molecular farming; plant extracts; respiratory diseases
Show Figures

Figure 1

MDPI and ACS Style

Abiri, R.; Abdul-Hamid, H.; Sytar, O.; Abiri, R.; Bezerra de Almeida, E., Jr.; Sharma, S.K.; Bulgakov, V.P.; Arroo, R.R.J.; Malik, S. A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov. Molecules 2021, 26, 3868. https://doi.org/10.3390/molecules26133868

AMA Style

Abiri R, Abdul-Hamid H, Sytar O, Abiri R, Bezerra de Almeida E Jr., Sharma SK, Bulgakov VP, Arroo RRJ, Malik S. A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov. Molecules. 2021; 26(13):3868. https://doi.org/10.3390/molecules26133868

Chicago/Turabian Style

Abiri, Rambod, Hazandy Abdul-Hamid, Oksana Sytar, Ramin Abiri, Eduardo Bezerra de Almeida Jr., Surender K. Sharma, Victor P. Bulgakov, Randolph R.J. Arroo, and Sonia Malik. 2021. "A Brief Overview of Potential Treatments for Viral Diseases Using Natural Plant Compounds: The Case of SARS-Cov" Molecules 26, no. 13: 3868. https://doi.org/10.3390/molecules26133868

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop