Immune Activity of Polysaccharide Fractions Isolated from Korean Red Ginseng
Abstract
:1. Introduction
2. Results and Discussion
2.1. Component Analysis
2.2. Weight Change of Immunity Organs
2.3. IgM Antibody-Forming Cells (AFCs) in Splenocyte against SRBCs
2.4. Phagocytosis Activity of Peritoneal Macrophage
2.5. Distribution of Spleen Lymphocyte
2.6. Discussion
3. Methods
3.1. Manufacture of Korean Red Ginseng
3.2. Production of Fractions
3.3. Component Analysis
3.4. Reagents and Analysis Devices
3.5. Animals
3.6. Sample Administration
3.7. Weight Measurement of Immune System Organs
3.8. Antibody-Forming Cells (AFCs) in Splenocytes against SRBCs
3.9. Phagocytosis Activity of Intraperitoneal Macrophage
3.10. Distribution of Spleen Lymphocyte
3.11. Statistical Analysis
4. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Sample Availability: Not available. |
Group | W 1 | RGNP 2 | RGAP 3 |
---|---|---|---|
Glucose | 2.40 | 1.14 | N/D 4 |
Fructose | 1.70 | 1.70 | N/D |
Sucrose | 1.53 | 1.70 | N/D |
Maltose | 5.10 | 5.80 | N/D |
Acidic polysaccharides | 7.46 | N/D 5 | 57.25 |
Ginsenosides 5 | 6.11 | 5.51 | N/D |
Experimental Group (mg/kg) | Absolute Organ Weight | Relative Organ Weight (g/100 g of Body Weight) | ||
---|---|---|---|---|
Spleen | Thymus | Spleen | Thymus | |
Normal | 112.8 ± 0.016 | 55.9 ± 0.008 | 0.47 ± 0.0007 | 0.23 ± 0.0003 |
CY Control | 84.4 ± 0.013 ** | 42.7 ± 0.009 ** | 0.37 ± 0.0005 ** | 0.17 ± 0.0004 ** |
CY + W100 | 88.3 ± 0.013 | 43.1 ± 0.007 | 0.37 ± 0.0007 | 0.18 ± 0.0003 |
CY + RGNP100 | 92.6 ± 0.015 | 44.4 ± 0.004 | 0.38 ± 0.0006 | 0.19 ± 0.0002 |
CY + RGAP100 | 94.3 ± 0.009 | 45.8 ± 0.005 | 0.4 ± 0.0004 | 0.19 ± 0.0002 |
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Youn, S.H.; Lee, S.M.; Han, C.-K.; In, G.; Park, C.-K.; Hyun, S.H. Immune Activity of Polysaccharide Fractions Isolated from Korean Red Ginseng. Molecules 2020, 25, 3569. https://doi.org/10.3390/molecules25163569
Youn SH, Lee SM, Han C-K, In G, Park C-K, Hyun SH. Immune Activity of Polysaccharide Fractions Isolated from Korean Red Ginseng. Molecules. 2020; 25(16):3569. https://doi.org/10.3390/molecules25163569
Chicago/Turabian StyleYoun, Soo Hyun, Sang Min Lee, Chang-Kyun Han, Gyo In, Chae-Kyu Park, and Sun Hee Hyun. 2020. "Immune Activity of Polysaccharide Fractions Isolated from Korean Red Ginseng" Molecules 25, no. 16: 3569. https://doi.org/10.3390/molecules25163569