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Open AccessArticle

Anti-Hypochlorite and Catalytic Activity of Commercially Available Moringa oleifera Diet Supplement

1
Department of Analytical Chemistry (C1), Faculty of Chemical Engineering and Technology, Cracow University of Technology, Warszawska 24, 31-155 Cracow, Poland
2
Centre of Applied Science for Health, Technological University Tallaght, Dublin 24, Ireland
3
Department of Biophysics, University of Life Sciences in Lublin, Akademicka 13, 20-950 Lublin, Poland
*
Author to whom correspondence should be addressed.
Academic Editors: Margarida Castell Escuer and Mariona Camps-Bossacoma
Molecules 2019, 24(18), 3330; https://doi.org/10.3390/molecules24183330
Received: 2 August 2019 / Revised: 6 September 2019 / Accepted: 11 September 2019 / Published: 12 September 2019
(This article belongs to the Special Issue Natural Polyphenols and Health)
Aiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available Moringa oleifera dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochlorite activity of the extract was assessed using the hypochlorite-specific coumarin-based fluorescence turn-off sensor, namely 7-diethylamino-coumarin-3-carboxylic acid (7-DCCA). This compound was synthesized via the Knoevenagel condensation of 4-diethylamino-2-hydroxybenzaldehyde with Meldrum’s acid and the Moringa extract was employed as a medium and catalyst. Moreover, the total phenolic content (TPC) as well as the reactive oxygen species (ROS)–scavenging ability of the aqueous Moringa extract were determined. The results obtained demonstrated the applicability of Moringa extract as an anti-hypochlorite agent. Additionally, the satisfactory yield of the 7-DCCA obtained suggests the usefulness of the extract as a catalyst and the reaction medium. The antioxidative potential of the extract was notably lower than that of the standard (TROLOX). Determination of TPC in 100 g of the dry weight (DW) of studied material revealed a high number of polyphones present. View Full-Text
Keywords: Moringa oleifera; hypochlorite; scavenging; free radicals; antioxidative potential; inflammation; coumarins; DPPH Moringa oleifera; hypochlorite; scavenging; free radicals; antioxidative potential; inflammation; coumarins; DPPH
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MDPI and ACS Style

Starzak, K.; Creaven, B.; Matwijczuk, A.; Matwijczuk, A.; Karcz, D. Anti-Hypochlorite and Catalytic Activity of Commercially Available Moringa oleifera Diet Supplement. Molecules 2019, 24, 3330.

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