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Open AccessArticle

Polyphenol Composition and (Bio)Activity of Berberis Species and Wild Strawberry from the Argentinean Patagonia

1
Laboratorio Ecotono, INIBIOMA (CONICET-Universidad Nacional del Comahue), Bariloche 8400, Río Negro, Argentina
2
Laboratorio de Cultivo Celular, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 3460000, Region del Maule, Chile
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Laboratorio de Química de Productos Naturales, Instituto de Química de Recursos Naturales, Universidad de Talca, Talca 3460000, Region del Maule, Chile
4
Instituto Regional de Investigación Científica Aplicada, Departamento de Química Analítica y Tecnología de Alimentos, Universidad Castilla-La Mancha, 13005 Ciudad Real, Spain
5
Departamento de Ciencias Básicas Biomédicas, Facultad de Ciencias de la Salud, Universidad de Talca, Talca 346000, Región del Maule, Chile
*
Author to whom correspondence should be addressed.
Molecules 2019, 24(18), 3331; https://doi.org/10.3390/molecules24183331
Received: 5 August 2019 / Revised: 30 August 2019 / Accepted: 2 September 2019 / Published: 12 September 2019
(This article belongs to the Section Natural Products Chemistry)
The Argentinean Patagonia berries Berberis microphylla, Berberis darwinii, and Fragaria chiloensis ssp. chiloensis f. patagonica were investigated for their polyphenol content and composition by means of liquid chromatography coupled to diode array detection and electrospray ionization tandem mass spectrometry. The in vitro antioxidant activity and inhibition of metabolic syndrome-associated enzymes (α-glucosidase, α-amylase, and lipase) of the fruit extracts was assessed. The most complex polyphenol profile was found in the Berberis samples, with 10 anthocyanins, 27 hydroxycinnamic acids, 3 proanthocyanidins, 2 flavan-3-ol, and 22 flavonols. Fragaria presented four anthocyanins, nine ellagitannins, two proanthocyanidin dimers, one flavan-3-ol, and five flavonols. The Berberis samples showed the best antioxidant capacity, while Fragaria displayed better activity against α-glucosidase and lipase. The phenolic content and composition of the Argentinean Patagonia berries was similar to that reported for Chilean samples but with some chemical differences between Eastern (Argentina) and Western (Chile) Patagonia. The data obtained supports the consumption of these berries as sources of beneficial polyphenols. View Full-Text
Keywords: Berberis microphylla; Berberis darwinii; Fragaria chiloensis ssp. chiloensis f. patagonica; HPLC-DAD-ESI-MSn; anthocyanins; phenolic compounds; antioxidant capacity; Patagonia Berberis microphylla; Berberis darwinii; Fragaria chiloensis ssp. chiloensis f. patagonica; HPLC-DAD-ESI-MSn; anthocyanins; phenolic compounds; antioxidant capacity; Patagonia
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MDPI and ACS Style

Chamorro, M.F.; Reiner, G.; Theoduloz, C.; Ladio, A.; Schmeda-Hirschmann, G.; Gómez-Alonso, S.; Jiménez-Aspee, F. Polyphenol Composition and (Bio)Activity of Berberis Species and Wild Strawberry from the Argentinean Patagonia. Molecules 2019, 24, 3331.

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