Next Article in Journal
Green Synthesis of Privileged Benzimidazole Scaffolds Using Active Deep Eutectic Solvent
Previous Article in Journal
Alnus Sibirica Extracts Suppress the Expression of Inflammatory Cytokines Induced by Lipopolysaccharides, Tumor Necrosis Factor-α, and Interferon-γ in Human Dermal Fibroblasts
Previous Article in Special Issue
Carbon Nanomaterial Doped Ionic Liquid Gels for the Removal of Pharmaceutically Active Compounds from Water
Article Menu

Export Article

Open AccessArticle

Enzyme Entrapment in Amphiphilic Myristyl-Phenylalanine Hydrogels

1
Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, ON M5S 3E5, Canada
2
Department of Physical and Environmental Sciences, University of Toronto Scarborough, 1065 Military Trail, Scarborough, ON M1C 1A4, Canada
3
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada
*
Author to whom correspondence should be addressed.
Academic Editors: Francesca D’Anna, Salvatore Marullo and Carla Rizzo
Molecules 2019, 24(16), 2884; https://doi.org/10.3390/molecules24162884
Received: 3 July 2019 / Revised: 25 July 2019 / Accepted: 5 August 2019 / Published: 8 August 2019
(This article belongs to the Special Issue Supramolecular Gel)
  |  
PDF [4493 KB, uploaded 16 August 2019]
  |  

Abstract

Supramolecular amino acid and peptide hydrogels are functional materials with a wide range of applications, however, their ability to serve as matrices for enzyme entrapment have been rarely explored. Two amino acid conjugates were synthesized and explored for hydrogel formation. These hydrogels were characterized in terms of strength and morphology, and their ability to entrap enzymes while keeping them active and reusable was explored. It was found that the hydrogels were able to successfully entrap two common and significant enzymes—horseradish peroxidase and α-amylase—thus keeping them active and stable, along with inducing recycling capabilities, which has potential to further advance the industrial biotransformation field. View Full-Text
Keywords: amino acids; protein; hydrogels; enzyme entrapment amino acids; protein; hydrogels; enzyme entrapment
Figures

Graphical abstract

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Falcone, N.; Shao, T.; Rashid, R.; Kraatz, H.-B. Enzyme Entrapment in Amphiphilic Myristyl-Phenylalanine Hydrogels. Molecules 2019, 24, 2884.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top