Next Article in Journal
Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis
Previous Article in Journal
Natural Scaffolds with Multi-Target Activity for the Potential Treatment of Alzheimer’s Disease
Previous Article in Special Issue
Synergistic Effect of Bioactive Anticarcinogens from Soybean on Anti-Proliferative Activity in MDA-MB-231 and MCF-7 Human Breast Cancer Cells In Vitro
Article Menu
Issue 9 (September) cover image

Export Article

Open AccessArticle
Molecules 2018, 23(9), 2180;

Anti-Bacterial Adhesion Activity of Tropical Microalgae Extracts

Institut Européen de la Mer, Université de Bretagne-Sud, EA 3884, LBCM, F-56100 Lorient, France
Laboratory c/o CYROL, NEXA, 97490 Sainte Clotilde, Reunion, France
MAPIEM, Biofouling et Substances Naturelles Marines, Université du Sud Toulon-Var, EA 4323, 83041 Toulon, France
Author to whom correspondence should be addressed.
Academic Editors: Paula B. Andrade and Patrícia Valentão
Received: 17 July 2018 / Revised: 27 August 2018 / Accepted: 29 August 2018 / Published: 29 August 2018
(This article belongs to the Special Issue Biological Potential of Marine and Terrestrial Species)
Full-Text   |   PDF [5465 KB, uploaded 29 August 2018]   |  


The evolution of regulations concerning biocidal products aimed towards an increased protection of the environment (e.g., EU Regulation No 528/2012) requires the development of new non-toxic anti-fouling (AF) systems. As the marine environment is an important source of inspiration, such AF systems inhibiting the adhesion of organisms without any toxicity could be based on molecules of natural origin. In this context, the antibiofilm potential of tropical microalgal extracts was investigated. The tropics are particularly interesting in terms of solar energy and temperatures which provide a wide marine diversity and a high production of microalgae. Twenty microalgal strains isolated from the Indian Ocean were studied. Their extracts were characterized in terms of global chemical composition by high resolution magic angle spinning (HR-MAS) and nuclear magnetic resonance (NMR) spectroscopy, toxicity against marine bacteria (viability and growth) and anti-adhesion effect. The different observations made by confocal laser scanning microscopy (CLSM) showed a significant activity of three extracts from Dinoflagellate strains against the settlement of selected marine bacteria without any toxicity at a concentration of 50 μg/mL. The Symbiodinium sp. (P-78) extract inhibited the adhesion of Bacillus sp. 4J6 (Atlantic Ocean), Shewanella sp. MVV1 (Indian Ocean) and Pseudoalteromonas lipolytica TC8 (Mediterranean Ocean) at 60, 76 and 52%, respectively. These results underlined the potential of using microalgal extracts to repel fouling organisms. View Full-Text
Keywords: tropical microalgae; antiadhesion activity; marine bacteria; dinoflagellates; Symbiodinium tropical microalgae; antiadhesion activity; marine bacteria; dinoflagellates; Symbiodinium

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Share & Cite This Article

MDPI and ACS Style

Zea-Obando, C.; Tunin-Ley, A.; Turquet, J.; Culioli, G.; Briand, J.-F.; Bazire, A.; Réhel, K.; Faÿ, F.; Linossier, I. Anti-Bacterial Adhesion Activity of Tropical Microalgae Extracts. Molecules 2018, 23, 2180.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Molecules EISSN 1420-3049 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top