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Molecules 2015, 20(3), 4483-4491;

Two New Phenolic Glucosides from Lagerstroemia speciosa

College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea
Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Korea
College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea
Department of Life Science, Hallym University, Chuncheon 200-702, Korea
Popa mountain park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar
College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang 410-820, Korea
Department of Forest Sciences, Seoul National University, Seoul 151-921, Korea
These authors contributed equally to this work.
Author to whom correspondence should be addressed.
Academic Editor: Derek J. McPhee
Received: 6 February 2015 / Revised: 4 March 2015 / Accepted: 5 March 2015 / Published: 10 March 2015
(This article belongs to the Section Natural Products Chemistry)
Full-Text   |   PDF [718 KB, uploaded 10 March 2015]   |  


Two new phenolic glucosides, 1-O-benzyl-6-O-E-caffeoyl-β-d-glucopyranoside and 1-O-(7S,8R)-guaiacylglycerol-(6-O-E-caffeoyl)-β-d-glucopyranoside, were isolated from the aerial parts of Lagerstroemia speciosa, along with ten known compounds. The structures of the isolated compounds were determined based on 1D- and 2D-NMR, Q-TOF MS and optical rotation spectroscopic data. All of the compounds showed moderate inhibitory activities against nitric oxide production in lipopolysaccharide-treated RAW264.7 cells, with IC50 values of 69.5–83.3 μM. View Full-Text
Keywords: Lagerstroemia speciosa; phenolic glucoside; inhibitory activities against nitric oxide production Lagerstroemia speciosa; phenolic glucoside; inhibitory activities against nitric oxide production

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Choi, J.; Cho, J.Y.; Choi, S.J.; Jeon, H.; Kim, Y.D.; Htwe, K.M.; Chin, Y.W.; Lee, W.S.; Kim, J.; Yoon, K.D. Two New Phenolic Glucosides from Lagerstroemia speciosa. Molecules 2015, 20, 4483-4491.

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