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Open AccessReview

Relative Stability of cis- and trans-Hydrindanones

Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan
Academic Editor: Derek J. McPhee
Molecules 2015, 20(1), 1509-1518;
Received: 14 November 2014 / Accepted: 14 January 2015 / Published: 15 January 2015
(This article belongs to the Section Organic Chemistry)
PDF [890 KB, uploaded 15 January 2015]


The relative stabilities of several cis- and trans-hydrindanones were compared using both isomerization experiments and MM2 calculations. The generally believed rule that cis-hydrindanones are more stable than trans-isomers is applicable, but is not always true. This review introduces examples, mainly from studies in our laboratory, to explain these facts. View Full-Text
Keywords: hydrindanones; isomerization; isomer; stereochemistry; stability; MM2 hydrindanones; isomerization; isomer; stereochemistry; stability; MM2

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Tori, M. Relative Stability of cis- and trans-Hydrindanones. Molecules 2015, 20, 1509-1518.

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