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Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs

Department of Chemistry, University of Rajasthan, Jaipur - 302 004 India
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Molecules 1997, 2(9), 129-134; https://doi.org/10.3390/20900129
Received: 10 April 1997 / Accepted: 1 August 1997 / Published: 5 September 1997
(±)cis-2-(4-Methoxyphenyl)-3-hydroxy/methoxy-2,3-dihydro-1,5-benzothiazepin-4[5H/5-chloroacetyl/5-(4'-methylpiperazino-1')acetyl]-ones have been synthesized by the condensation of 2-aminobenzene thiols with methyl(±)trans-3-(4-methoxyphenyl)glycidate in xylene. The synthesized compounds have been characterized by elemental analyses and spectral data and screened for their antimicrobial activity. View Full-Text
Keywords: 1; 5-Benzothiazepin derivatives; anticancer drugs 1; 5-Benzothiazepin derivatives; anticancer drugs
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Sharma, A.K.; Singh, G.; Yadav, A.K.; Prakash, L. Improved Method for the Synthesis of New 1,5-Benzothiazepine Derivatives as Analogues of Anticancer Drugs. Molecules 1997, 2, 129-134.

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