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Molecules 2011, 16(2), 1901-1909;

Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum

Laboratory for Natural Product Chemistry, College of Pharmacy, South Central University for Nationalities, Wuhan 430074, China
Guangxi Institute of Minority Medicine, Nanning 530001, China
Author to whom correspondence should be addressed.
Received: 15 November 2010 / Revised: 16 February 2011 / Accepted: 18 February 2011 / Published: 23 February 2011
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Three new steroidal glycosides, cyanoauriculosides F, G and H (1-3), were isolated from the roots of Cynanchum auriculatum (Asclepiadaceae) along with two known steroidal derivatives. On the basis of spectroscopic analysis and chemical methods, their structures were identified as 20-O-acetyl-8,14-seco-penupogenin-8-one 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (1), 2′,3′-Z-gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaro-pyranosyl-(1→4)-α-L-diginopyranosyl-(1→4)-β-D-cymaropyranoside (2), 17-O-acetyl-kidjoranin 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-cymaro-pyranosyl-(1→4)-β-D-digitoxopyranosyl-(1→4)-β-D-digitoxopyranoside (3), gagaminine 3-O-α-L-cymaropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-α-L-digino-pyranosyl-(1→4)-β-D-cymaropyranoside (4) and wilfoside D1N (5). View Full-Text
Keywords: Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides Cynanchum auriculatum; steroidal glycosides; cyanoauriculosides

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Lu, Y.; Teng, H.-L.; Yang, G.-Z.; Mei, Z.-N. Three New Steroidal Glycosides from the Roots of Cynanchum auriculatum. Molecules 2011, 16, 1901-1909.

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