Applications of Polymers and Polymer Nanomaterials in Drug Delivery and Nanomedicine, 2nd Edition

Abstract submission deadline

30 January 2027

Manuscript submission deadline

30 March 2027

Viewed by

1071

Topic Information

Dear Colleagues,

The focus of modern pharmaceutical science is aimed at the possibility for control, extension, sustaining, and targeting of the bioactive compounds. Moreover, the efforts are intended to overcome the limitations of the drugs itself, such as decreasing its toxicity and side effects, its instabilities, and unwanted changes. In the field of drug delivery science, polymers have seen significant progress. They provide the possibility for development of delivery systems of higher hierarchical order owing to their unique properties on a molecular and supramolecular level. Their possibility for improvement of the pharmacokinetic properties of drugs is practically unrestricted.

This topic is an attempt to summarize recent progress in the knowledge of drug delivery systems based on hydrogels, micro- and nanosized gels, biodegradable polymers, stimuli-responsive systems, polymer and polymer-hybrid nanoparticles, etc., in the development of alternative formulations and administration routes. The evolution of polymer based delivery systems of large molecules as well as biomolecules will also be addressed.

Prof. Dr. Stanislav Rangelov
Dr. Emi Haladjova
Topic Editors

Keywords

Participating Journals

Journal Name	Impact Factor	CiteScore	Launched Year	First Decision (median)	APC
Applied Nano applnano	-	4.6	2020	15.7 Days	CHF 1000	Submit
Biomolecules biomolecules	4.8	9.2	2011	17.9 Days	CHF 2700	Submit
Micro micro	1.9	3.2	2021	23.2 Days	CHF 1200	Submit
Nanomaterials nanomaterials	4.3	9.2	2010	14 Days	CHF 2400	Submit
Pharmaceuticals pharmaceuticals	4.8	7.7	2004	16 Days	CHF 2900	Submit
Pharmaceutics pharmaceutics	5.5	10.0	2009	15.7 Days	CHF 2900	Submit
Scientia Pharmaceutica scipharm	2.5	4.6	1930	22.8 Days	CHF 1000	Submit

Preprints.org is a multidisciplinary platform offering a preprint service designed to facilitate the early sharing of your research. It supports and empowers your research journey from the very beginning.

MDPI Topics is collaborating with Preprints.org and has established a direct connection between MDPI journals and the platform. Authors are encouraged to take advantage of this opportunity by posting their preprints at Preprints.org prior to publication:

1. Share your research immediately: disseminate your ideas prior to publication and establish priority for your work.
2. Safeguard your intellectual contribution: Protect your ideas with a time-stamped preprint that serves as proof of your research timeline.
3. Boost visibility and impact: Increase the reach and influence of your research by making it accessible to a global audience.
4. Gain early feedback: Receive valuable input and insights from peers before submitting to a journal.
5. Ensure broad indexing: Web of Science (Preprint Citation Index), Google Scholar, Crossref, SHARE, PrePubMed, Scilit and Europe PMC.

Related Topic

Published Papers (1 paper)

Order results

Content type Publication Date

Result details

Normal Extended Compact

Journals

All Biomolecules Micro Pharmaceuticals Pharmaceutics Nanomaterials Applied Nano Sci. Pharm.

Show export options expand_more Show export options expand_less

Select all

Export citation of selected articles as:

Plain Text BibTeX BibTeX (without abstracts) Endnote Endnote (without abstracts) Tab-delimited RIS

Error

Oops... you haven't selected anything for export.

Ok

clear

12 pages, 482 KB  

Open AccessArticle

Bioabsorbable Hydrogel Coating for Infection Prevention in Fracture Fixation: A Retrospective Matched Case–Control Study

by Carlo Ciccullo, Marco Grassi, Marco Antonio Carletti, Claudia Bevilacqua, Danilo Francesco Chirillo, Simone Domenico Aspriello and Antonio Pompilio Gigante

Pharmaceuticals 2026, 19(3), 518; https://doi.org/10.3390/ph19030518 - 23 Mar 2026

Viewed by 282

Abstract

Background/Objectives: Hospital-acquired and fracture-related infections remain major complications in orthopedic trauma surgery, with significant clinical and socio-economic impact. Antibacterial implant surface coatings represent a promising strategy to reduce early postoperative bacterial adhesion and biofilm formation. Methods: This retrospective matched case–control study [...] Read more.

Background/Objectives: Hospital-acquired and fracture-related infections remain major complications in orthopedic trauma surgery, with significant clinical and socio-economic impact. Antibacterial implant surface coatings represent a promising strategy to reduce early postoperative bacterial adhesion and biofilm formation. Methods: This retrospective matched case–control study evaluated the clinical effectiveness of an antibiotic-free fast-resorbable hyaluronic acid and poly-d, l-lactide hydrogel (DAC^®) applied intraoperatively to orthopedic implants. A total of 222 patients with comorbidities who underwent open reduction and internal fixation between May 2023 and April 2024 in two trauma centers were included: 99 patients received the DAC^® coating and 123 served as controls with standard fixation. The primary endpoint was infection incidence within 6 months; secondary endpoints included wound complications, revision surgery, prolonged antibiotic therapy, and bone healing. Results: Postoperative infection incidence was significantly lower in the DAC^® group compared with controls (0.7% vs. 5.3%; p = 0.0363). Wound complications were also reduced (1.3% vs. 8.0%; p = 0.028), and only one patient in the DAC^® cohort required additional surgical interventions or prolonged antibiotic therapy. Bone healing outcomes were comparable between groups, with no delayed unions reported in the treated cohort. Conclusions: Even if larger prospective studies with longer follow-up are required to further confirm these findings and better define long-term safety and effectiveness, the routine intraoperative use of DAC^® hydrogel without antibiotic loading appears to be a safe and promising strategy to reduce early postoperative infections and wound complications in orthopedic trauma patients with comorbidities. Full article

(This article belongs to the Topic Applications of Polymers and Polymer Nanomaterials in Drug Delivery and Nanomedicine, 2nd Edition)

►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less

Select all

Export citation of selected articles as:

Plain Text BibTeX BibTeX (without abstracts) Endnote Endnote (without abstracts) Tab-delimited RIS

 

Error

Oops... you haven't selected anything for export.

Ok

clear

Displaying articles 1-1