Search Results (1,056)

Background/Objectives: Chronic cervical myofascial pain syndrome (CMPS) is often diagnosed in the current population by doctors of various specialties. One method of treating spinal pathology is mesotherapy. The purpose of this study is to evaluate the efficacy and safety of collagen mesotherapy, as well as to assess the frequency of pain medication after mesotherapy in chronic CMPS. Methods: Patients were diagnosed and treated by an orthopedist in three different offices between 1 January 2018 and 31 December 2024. The patients were diagnosed with chronic CMPS. Patients were qualified for cervical spine mesotherapy, which was performed weekly, in five repetitions. Retrospectively, based on medical records and in accordance with inclusion and exclusion criteria, two groups were created: group I (n = 65) with injectable type I collagen and group II (n = 65) with 1% lignocaine. Patients were evaluated using the VAS and Laitinen scale before the start of therapy, 1 week after the end of therapy, and at 3-month follow-up. In addition, the frequency of taking analgesic medications after mesotherapy was assessed. Results: After mesotherapy of the cervical spine with both injectable collagen type I and lignocaine 1%, statistically significant improvements were observed in terms of a decrease in pain on the scales used (p < 0.001), as well as a decrease in analgesic medication intake (p < 0.001). Collagen treatment yielded better results after 3 months of follow-up. No mesotherapy-related side effects were observed during the treatment or follow-up periods. Conclusions: Cervical spine mesotherapy using injectable type I collagen and lignocaine 1% is an effective and safe method for chronic CMPS. At a 3-month follow-up, injectable type I collagen appears to be more effective. After mesotherapy and at the 3-month follow-up, both groups reported less pain medication intake compared to before the intervention. Full article

Introduction: The main purpose of this study was to test a hierarchical model of motivation that integrates Achievement Goal Theory and Self-Determination Theory to explain and predict exercise adherence. Method: In total, 2180 exercisers (1020 female, 1160 male) aged between 18 and 60 years, from different gyms and health clubs, completed several scales validated in exercise settings, regarding perceived motivational climate, basic psychological need satisfaction, behavioral regulation, and exercise adherence. For the last measure, weekly computer access to a control system over a 6-month period before and after data collection was consulted. Results: Through structural equation models (SEM), it was verified that (1) task-involving climate positively predicted basic psychological needs. In turn, the satisfaction of these needs predicted autonomous motivation, which led to a positive prediction of adherence; (2) a small variation in exercise adherence was explained by the motivational model under analysis. Nevertheless, models significantly improved their analytical power when past adherence was inserted in the model increasing the explained variance in future behavior from 9.2% to 64%. Conclusions: In conclusion, autonomous motivation can predict people’s exercise adherence, and past behavior increases that predictive effect. The present study brings scientific evidence to the popular saying “tell me what you’ve done and, and I’ll predict what you’ll do”. Full article

The cecal microbiota is essential for intestinal health and performance. This study describes the succession patterns of the cecal microbiota in Japanese quail (Coturnix japonica) until 42 days of age. Sixty quails were raised using standard conditions and fed corn–soybean meal diets. Cecal contents were sampled from five birds weekly from 7 to 42 days of age and submitted to Illumina 16S rRNA sequencing for metabarcoding analysis. Diversity and functional prediction were carried out with QIIME2, PICRUSt2, STAMP and MicrobiomeAnalyst 2.0. Firmicutes increased from 50% at 7 days to more than 80% at 42 days, whereas Bacteroidota decreased from 45% to 12% in the same period. Alpha diversity progressively increased with age, indicating a richer and more balanced microbiota at later ages. Genera such as Bacteroides were predominant in the beginning and later were replaced by Lachnospiraceae, Ruminococcus and Faecalibacterium. These developmental taxonomic features aligned with significant shifts in ten metabolic pathways identified by prediction, revealing a transition from biosynthetic functions to complex carbohydrate metabolism and cell wall biosynthesis. The first seven days are considered a critical window for probiotics intervention, which may favor the establishment of a microbiota that is more stable and beneficial to quail performance. Full article

Background: Soccer is a physically demanding sport characterized by frequent high-intensity efforts, which are particularly relevant in women’s competitions. Improving high-speed running and aerobic capacity has been linked to better on-field performance. Strength training has shown promise in enhancing these physical attributes, but its application in young female soccer players remains underexplored. This study aimed to investigate the effects of a 10-week in-season strength training program on physical performance and match running demands in young female soccer players. Methods: Thirty-two U18 Danish female professional soccer players from two comparable teams voluntarily participated in the study. Teams were allocated to either an experimental group, performing twice-weekly strength training (EG, n = 16) or a control group (CG, n = 16). Vertical jump performance and Yo-Yo IR2 performance as an estimation for maximal oxygen uptake (VO₂max) were assessed both pre and post intervention. Additionally, players’ match external demands (i.e., total distance, distance covered at speeds above 23 km·h⁻¹, and maximum velocity achieved) were monitored using Global Positioning System devices during four matches before and after the intervention. Results: Significant within-group differences were observed across all variables for the EG (p = 0.001; ES = 1.08 to 1.45, large), without differences in the CG (p > 0.01). Between-group analysis indicated significant differences favoring the EG in all variables (F = 27.40 to 47.17; p = 0.001). Conclusions: The application of a 10-week strength training program led to improvements in physical and match running performance among young female soccer players, underscoring the importance of incorporating strength training programs into female soccer periodization to enhance performance. Full article

Crop fidelity is a desirable trait for managed pollinators and is influenced by factors like competing forage sources and colony knowledge of the surrounding environment. In European honey bees (Apis mellifera L.), colonies deployed when the crop is flowering display the highest fidelity. We tested for a similar outcome using a stingless bee species that is being increasingly used as a managed pollinator in Australian macadamia orchards. We observed Tetragonula carbonaria (Smith) colonies deployed in macadamia orchards at three time points: (1) before crop flowering (“permanent”), (2) early flowering (“early”), and (3) later in the flowering period (“later”). We captured returning pollen foragers weekly and estimated crop fidelity from the proportion of macadamia pollen they collected, using light microscopy. Pollen foraging activity was also assessed via weekly hive entrance filming. The early and later introduced colonies initially exhibited high fidelity, collecting more macadamia pollen than the permanent colonies. In most cases, the permanent colonies were already collecting diverse pollen species from the local environment and took longer to shift over to macadamia. Pollen diversity increased over time in all colonies, which was associated with an increase in the proportion of pollen foragers. Our results indicate that stingless bees can initially prioritize a mass-flowering crop, even when flowering levels are low, but that they subsequently reduce fidelity over time. Our findings will inform pollinator management strategies to help growers maximize returns from pollinator-dependent crops like macadamia. Full article

Background: Rapid loss of residual kidney function (RKF) is associated with unfavorable outcomes. We conducted an RCT to compare the effects on RKF preservation of incremental HD between once-weekly HD (1-WHD) and twice-weekly HD (2-WHD). Methods: ESKD patients with an eGFR of 5–10 mL/min/1.73 m² and urine output of ≥800 mL/day were randomly assigned to receive either once-weekly HD (1-WHD) or twice-weekly HD (2-WHD) for 12 months. Patients in the 1-WHD group were prescribed once-weekly HD combined with low-protein diet (0.6 g/kg/day) supplemented with keto-analogues (KAs) 0.12 g/kg/day. In the 2-WHD group, patients received twice-weekly HD with a regular-protein diet. Primary outcomes were changes in RKF by renal clearance and urine volume. Nutritional status, muscle parameters, and quality of life (QoL) were also assessed. Results: A total of 30 incident HD patients were randomized. Baseline RKF, urine volume, and demographic were not different between groups. After 3 months, urine volume was significantly higher in the 1-WHD group than in the 2-WHD group (1921 ± 767 mL/day vs. 1305 ± 599 mL/day, p = 0.02), and these significant findings persisted throughout the entire study period. For RKF, 1-WHD also had a lesser decline in urinary urea (CUrea) and creatinine clearance (CCr) than 2-WHD, with statistically significant differences observed from months 6–12. By month 6, the 1-WHD group exhibited significantly higher CUrea and CCr compared to the 2-WHD group, with CUrea at 3.2 ± 2.3 vs. 1.7 ± 1.0 mL/min (p = 0.03) and CCr at 5.9 ± 3.6 vs. 3.8 ± 1.4 mL/min (p = 0.04), respectively. Serum albumin levels, skeletal muscle mass, anemia status, metabolic parameters, protein-bound uremic toxins, and QoL scores were comparable between the two groups. Conclusions: Incremental HD, starting with once-weekly HD combined with protein restriction supplemented with KAs, appears to better preserve RKF among incident HD patients compared to twice-weekly HD with a regular-protein diet. This HD regimen was also associated with safety in metabolic and nutritional profiles. Full article

This study analyses the physical performance variables involved in different training tasks aimed at replicating the worst-case scenarios (WCSs) observed during official matches in professional football, with a focus on playing positions and occurrences within a 1 min period. Data were collected from 188 training sessions and 42 matches of a Spanish Second Division team during the 2021/2022 season. All data were reported on a per-player basis. GPS tracking devices were used to record physical variables such as total distance, high-speed running (HSR), sprints, accelerations, decelerations, and high metabolic load distance (HMLD). Players were grouped according to their match positions: central defenders, wide players, midfielders and forwards. The results showed that none of the training tasks fully replicated the physical demands of match play. However, task TYPEs 11 (Large-Sided Games) and 9 (small-sided games with orientation and transition) were the closest to match demands, particularly in terms of accelerations and decelerations. Although differences were observed across all variables, the most pronounced discrepancies were observed in sprint and HSR variables, where training tasksfailed to reach 60% of match demands. These findings highlight the need to design more specific drills that simulate the intensity of WCS, allowing for more accurate weekly training load planning. This study offers valuable contributions for optimising performance and reducing injury risk in professional footballers during the competitive period. Full article

In this paper, the authors introduce the transmuted geometric integer-valued autoregressive model with periodicity, designed specifically to analyze epidemiological and public health time series data. The model uses a transmuted geometric distribution as a marginal distribution of the process. It also captures varying tail behaviors seen in disease case counts and health data. Key statistical properties of the process, such as conditional mean, conditional variance, etc., are derived, along with estimation techniques like conditional least squares and conditional maximum likelihood. The ability to provide k-step-ahead forecasts makes this approach valuable for identifying disease trends and planning interventions. Monte Carlo simulation studies confirm the accuracy and reliability of the estimation methods. The effectiveness of the proposed model is analyzed using three real-world public health datasets: weekly reported cases of Legionnaires’ disease, syphilis, and dengue fever. Full article

Curcuma spp. is a popular ornamental crop valued for its vibrant appearance and suitability for both regular and off-season production. As global emphasis on freshwater conservation increases and with a demand for compact potted plants, reducing water use while maintaining high aesthetic quality presents a key challenge for horticulturists. Potassium silicate (PS) has been proposed as a foliar spray to alleviate plant water stress. This study aimed to evaluate the effects of PS on growth, ornamental traits, and photosynthetic parameters of off-season potted Curcuma cv. ‘Jasmine Pink’ under deficit irrigation (DI). Plants were subjected to three treatments in a completely randomized design: 100% crop evapotranspiration (ETc), 50% ETc, and 50% ETc with 1000 ppm PS (weekly sprayed on leaves for 11 weeks). Both DI treatments (50% ETc and 50% ETc + PS) reduced plant height by 7.39% and 9.17%, leaf number by 16.99% and 7.03%, and total biomass by 21.13% and 20.58%, respectively, compared to 100% ETc. Notably, under DI, PS-treated plants maintained several parameters equivalent to the 100% ETc treatment, including flower bud emergence, blooming period, green bract number, effective quantum yield of PSII (ΔF/Fm′), and electron transport rate (ETR). In addition, PS application increased leaf area by 8.11% and compactness index by 9.80% relative to untreated plants. Photosynthetic rate, ΔF/Fm′, and ETR increased by 31.52%, 13.63%, and 9.93%, while non-photochemical quenching decreased by 16.51% under water-limited conditions. These findings demonstrate that integrating deficit irrigation with PS foliar application can enhance water use efficiency and maintain ornamental quality in off-season potted Curcuma, promoting sustainable water management in horticulture. Full article

Promoting behavioral change in mobility is essential for sustainable urban development. This study evaluates the effectiveness of gamified challenges in fostering sustainable travel behaviors among high school students and teachers within the High School Challenge (HSC) 2024 campaign in Lecco, Italy. Over a 13-week period, participants tracked their commuting habits via gamified mobile application, Play&Go, that awarded points for sustainable mobility choices and introduced weekly challenges. Using behavioral (GPS-based tracking) and self-report data, we assessed the influence of challenge types, player characteristics (HEXAD Player Types, Big Five traits), and user experience evaluations on participation, retention, and behavior change. The results show that challenges, particularly those based on walking distances and framed as intra-team goals, significantly enhanced user engagement and contributed to improved mobility behaviors during participants’ free time. Compared to the 2023 edition without challenges, the 2024 campaign achieved better retention. HEXAD Player Types were more predictive of user appreciation than Personality Traits, though these effects were more evident in subjective evaluations than actual behavior. Overall, findings highlight the importance of tailoring gamified interventions to users’ motivational profiles and structuring challenges around SMART principles. This study contributes to the design of behaviorally informed, scalable solutions for sustainable mobility transitions. Full article

This paper clarified the correlation among quality of life (QoL) indicators, exercise implementation level, and exercise habits in middle-aged and older adults under identical exercise intervention conditions. The survey items were anthropometric and physiologic measurements, physical strength measurements, and exercise habits. During the 3-month experimental period, a weekly “health exercise course” served as the primary intervention. For all participants, anthropometric and physiologic measurements, physical strength tests, questionnaire surveys, and other surveys were conducted before and after the experiment; then, the pre- and post-intervention effects were compared. After the exercise intervention, significant differences were observed among middle-aged and older adults in terms of various parameters, such as weight, fat rate, diastolic pressure, systolic pressure, sit-up, standing on one foot, lower limb extension force, activity of daily living (ADL), and subjective well-being (PGC). ADL and PGC changed significantly in the participants who engaged in exercise more than twice a week. However, the participants who engaged in exercise for less than twice a week showed no significant differences in any parameters except the life satisfaction (LSI) mean; the LSI increased in the “Less than twice a week” exercise group but decreased in the “More than twice a week” group. In terms of average walking time per session, the “More than 30 min” exercise group showed significant differences in ADL and PGC, whereas the “Less than 30 min” group showed significant differences only in the LSI. The influence of exercise on QoL indicators of middle-aged and older adults, under the same exercise intervention conditions, is related to their exercise habits. This study highlights the benefits of physical exercise in middle-aged and older adults, emphasizing the importance of regular and sustained exercise for this population. Furthermore, the study provides a scientific basis for improving QoL in middle-aged and older adults, thus, to some extent, addressing the concerns related to the growing population of older adults. Full article

This study investigated the seasonal and spatial dynamics of off-flavour compounds—geosmin and 2-methylisoborneol (2-MIB)—in an intensive rainbow trout (Oncorhynchus mykiss) aquaculture system for human consumption in western Spain. Weekly water and fish flesh samples were collected over a 12-month period from three farms supplied by the River Tormes. Physicochemical parameters, determination of geosmin and 2-MIB by SPME-GC-MS, microbial counts, and microbial community composition were assessed alongside volatile compound concentrations. Geosmin and 2-MIB showed marked seasonal variation, with peak levels in water and fish flesh during spring and summer, correlating positively with temperature. Geosmin accumulation in fish was highest in the downstream farm, suggesting cumulative exposure effects. In contrast, 2-MIB was detected only in water and at lower concentrations. Microbial analyses revealed high bacterial and fungal diversity, including cyanobacterial taxa such as Phormidium setchellianum and Pseudoanabaena minima, known producers of geosmin and 2-MIB. These findings highlight the importance of water microbiota and environmental conditions in off-flavour development. Managing cyanobacterial populations and monitoring spatial-temporal variability are essential to mitigate the development of earthy or musty flavours and economic losses in aquaculture systems. Full article

Food waste is a global sustainability issue, and in Japan, approximately half of all food waste is generated in households. This study focused on refrigerator management behaviors aimed at using up the food inventory in the home. An intervention study involving 119 households with two or more members across Japan, with a two-week baseline period and a two-week intervention, was conducted. Target behaviors were set as “search food that should be eaten quickly,” “move it to a visible place,” and “use the foods that should be eaten quickly,” and tools to support these behaviors were selected, including an organizer for the refrigerator, photos, and food management apps. Each tool was assigned to approximately 30 households, and a control group was established. Food waste was measured using a cloud-based automatic weighing system, and all participants were asked to separate avoidable food waste at home and dispose of it in the designated waste bin. During the intervention period, the average weekly food waste per household decreased by 29% to 51% in the intervention group, while there was little change in the control group. An analysis using a two-way mixed ANOVA revealed a marginally significant interaction (p < 0.10), indicating moderate effectiveness. Among the behaviors contributing to reduced food waste, three actions—“having trouble not being able to recall food inventory at home during shopping,” “moving foods that should be used sooner,” and “organizing refrigerator”—showed significant interaction effects (p < 0.05) in a two-way mixed ANOVA, indicating the effectiveness of the intervention. Full article

The spotted wing drosophila, Drosophila suzukii is an injurious polyphagous pest threatening worldwide soft fruit production. Its high adaptability to new colonized environments, short life cycle, and wide host range are supporting its rapid spread. The most common techniques to reduce its significant economic damage are based on multiple insecticides applications per season, even prior to the harvest, which reduces agroecosystem biodiversity and affects human and animal health. Environmental concerns and regulatory restrictions on insecticide use are driving the need for studies on alternative biological control strategies. This study aimed to assess the effect of T. drosphilae in controlling D. suzukii infestations and its interaction with P. vindemiae, a secondary parasitoid naturally present in Apulia (South Italy). Field experiments were carried out in organic cherry orchards in Gioia del Colle (Bari, Italy) to test the efficacy and adaptability of T. drosphilae following weekly releases of artificially reared individuals. Additionally, the interaction between P. vindemiae and T. drosphilae was studied under laboratory conditions. Results from field experiments showed that D. suzukii populations were significantly lower when both parasitoids were present. However, T. drosophilae was less prone to adaptation, so its presence and parasitism were limited to the post-release period. Laboratory experiments, instead, confirmed the high reduction of D. suzukii populations when both parasitoids are present. However, the co-existence of the two parasitoids resulted in a reduced parasitism rate and offspring production, notably for T. drosophilae. This competitive disadvantage may explain its poor establishment in field conditions. These findings suggest that the field release of the two natural enemies should be carried out with reference to their natural population abundance to not generate competition effects. Full article

Objective: This study aims to investigate the feasibility of an online music therapy protocol for individuals previously diagnosed with COVID-19, focusing on their perceptions of their respiratory symptoms and the intervention’s impact on psychosocial measures. Methods: A within-subject experimental design was applied to examine an eight-week weekly online music therapy protocol, including singing, wind instrument playing, and music visualizations. All self-report data were collected bi-weekly throughout the 16-weeks study period, including baseline and post-tests. The measures for respiratory symptoms included the Medical Research Council’s Dyspnea Scale (MRC Dyspnea), Chronic Respiratory Questionnaire-Mastery Scores (CRQ Mastery), and Visual Analogue Scale for breathlessness. The measures for the secondary psychosocial outcomes were the Beck Depression Inventory-Short Form, the Generalized Anxiety Disorder 7-item, the Hospital Anxiety and Depression Scale, the Fatigue Severity Scale, the Epworth Sleepiness Scale, the EuroQol 5-Dimension 5-Level, and the Connor-Davidson Resilience Scale. Results: Twenty-four participants were enrolled. The participants perceived a reduction in respiratory symptoms, and shortness of breath (MRC Dyspnea). Planned comparisons showed significant decreases in MRC from baseline to post-treatment (p = 0.008). The mixed-effects model, including pre-baseline and post-treatment, was significant (p < 0.001). Significant changes in Breathing VAS were consistent with improvements in MRC Dyspnea, showing a significant baseline-to-post difference (p = 0.01). The CRQ Mastery showed significant improvements from baseline to Week 12 (p < 0.001). No significant changes were observed in other secondary measures. Conclusions: Our preliminary findings suggest that this protocol is feasible, and as a result, may help individuals previously diagnosed with COVID-19 to cope with lasting respiratory symptoms and improve their perception of shortness of breath. Live music-making, including playing accessible wind instruments and singing, may contribute to an increase sense of control over breathing. As this was a feasibility study, we conducted multiple uncorrected statistical comparisons to explore potential effects. While this approach may increase the risk of Type I error, the findings are intended to inform hypotheses for future confirmatory studies rather than to draw definitive conclusions. Full article