Search Results (938)

Background: The use of lower limb prosthesis can impact all aspects of daily life, activities and participation. Various studies have compared the microprocessor-controlled knee (MPK) to the non-microprocessor-controlled knee (NMPK) using a variety of different outcome measures, but results are inconsistent and raise the question of which type of knee is most effective. Therefore, we aimed to assess the effect of MPKs compared to NMPKs across all classified ICF domains in adult prosthesis users. Methods: Participants performed baseline measurements with the NMPK (T0). One week later, they started a four-to-six-week trial period with the MPK. Afterward, measurements were repeated with the MPK (T1). Functional tests (6MWT, TUG-test and activity monitor) and questionnaires (ABC, SQUASH, USER-P and PEQ) were used. For statistical analyses, paired t-tests, Wilcoxon signed-rank tests and Chi² test were applied. The Benjamini–Hochberg procedure was applied to correct for multiple testing. Results: Twenty-five participants were included. Using an MPK compared to an NMPK significantly resulted in improvements in balance and walking confidence, safety, walking distance and self-reported walking ability, as well as a decrease in number of stumbles and falls. Additionally, participants using an MPK were significantly more satisfied with their participation, experienced fewer restrictions, reported greater satisfaction with the appearance and utility of the MPK, experienced less social burden and reported better well-being, compared to using an NMPK. Conclusions: Using an MPK instead of an NMPK can lead to significant improvements in all classified ICF domains, such as improved walking ability, confidence and satisfaction and reduced fall risk. Full article

Firstly, this paper reviews the fundamental theories of solid surface wettability and contact angle hysteresis. Subsequently, it further introduces four typical wettability-engineered surfaces with low hysteresis (superhydrophobic, superamphiphobic, super-slippery, and liquid-like smooth surfaces). Finally, it focuses on the latest research progress in the field of droplet manipulation on open planar surfaces with engineered wettability. To achieve droplet manipulation, the core driving forces primarily stem from natural forces guided by bioinspired gradient surfaces or the regulatory effects of external fields. In terms of bioinspired self-propelled droplet movement, this paper summarizes research inspired by natural organisms such as desert beetles, cacti, self-aligning floating seeds of emergent plants, or water-walking insects, which construct bioinspired special gradient surfaces to induce Laplace pressure differences or wettability gradients on both sides of droplets for droplet manipulation. Moreover, this paper further analyzes the mechanisms, advantages, and limitations of these self-propelled approaches, while summarizing the corresponding driving force sources and their theoretical formulas. For droplet manipulation under external fields, this paper elaborates on various external stimuli including electric fields, thermal fields, optical fields, acoustic fields, and magnetic fields. Among them, electric fields involve actuation mechanisms such as directly applied electrostatic forces and indirectly applied electrocapillary forces; thermal fields influence droplet motion through thermoresponsive wettability gradients and thermocapillary effects; optical fields cover multiple wavelengths including near-infrared, ultraviolet, and visible light; acoustic fields utilize horizontal and vertical acoustic radiation pressure or acoustic wave-induced acoustic streaming for droplet manipulation; the magnetic force acting on droplets may originate from their interior, surface, or external substrates. Based on these different transport principles, this paper comparatively analyzes the unique characteristics of droplet manipulation under the five external fields. Finally, this paper summarizes the current challenges and issues in the research of droplet manipulation on the open planar surfaces and provides an outlook on future development directions in this field. Full article

Introduction: Hip abductor strength is essential for pelvic stability, lower limb alignment, and injury prevention. Weaknesses of the gluteus medius and minimus contribute to various musculoskeletal conditions. Lateral band walks and monster walks are elastic resistance exercises commonly used to target the hip abductors and external rotators in functional, weight-bearing tasks. Therefore, the aim was to summarize the current evidence on the biomechanics, muscle activation, and clinical applications of lateral and monster band walks. Methods: This narrative review was conducted following the SANRA guideline. A comprehensive literature search was performed across PubMed, Scopus, Web of Science, and SPORTDiscus up to April 2025. Studies on the biomechanics, electromyography, and clinical applications of lateral band walks and monster walks were included, alongside relevant evidence on hip abductor strengthening. Results: A total of 13 studies were included in the review, of which 4 specifically investigated lateral band walk and/or monster walk exercises. Lateral and monster walks elicit moderate to high activation of the gluteus medius and maximus, especially when performed with the band at the ankles or forefeet and in a semi-squat posture. This technique minimizes compensation from the tensor fasciae latae and promotes selective gluteal recruitment. Proper execution requires control of the trunk and pelvis, optimal squat depth, and consistent band tension. Anatomical factors (e.g., femoral torsion), sex differences, and postural variations may influence movement quality and necessitate tailored instruction. Full article

The world is facing a state of “global boiling,” causing damage to various sectors. Developing pedestrian systems is a key to mitigating it, especially in tropical and humid cities where the climate discourages walking and increases the need for shaded walkways. Recent research shows a lack of data and in-depth studies on the built environment promoting walkability in such climates, creating a research gap this study aims to fill. Using Singapore as a case study, four locations—Marina Bay, Orchard Road, Boat Quay, and Chinatown—were surveyed and analyzed through visual decoding and questionnaires. Results show that natural light is the most frequently observed and important element in pedestrian pathway design in tropical and humid areas. Trees and sidewalks are also important in creating a walk-friendly environment. Green spaces significantly influence the desire to walk, though no clear positive outcomes were found. Additionally, “Other Emotions” negatively affect the decision to walk, suggesting these should be avoided in future pedestrian pathway designs to encourage walking. Full article

Background/Objectives: Prehabilitation is a multimodal intervention introduced in preparation for various surgical procedures. The most effective treatment for obesity is bariatric surgery. Physiotherapy during prehabilitation for bariatric surgery may be an effective method of functional capacity improvement. We aimed to evaluate the impact of an individual outpatient 12-week, exercise-based physiotherapy program featuring prehabilitation on functional status, exercise tolerance, everyday mobility, and fatigue among patients qualified for bariatric surgery. Methods: The completion of an individual outpatient 12-week, exercise-based physiotherapy program during prehabilitation was an inclusion criterion for the study group. Participants included in the study and control groups were assessed twice, after enrollment into the prehabilitation program (the first assessment) and after prehabilitation but before surgery (the second assessment). Both assessments involved functional tests (a six-minute walking test [6MWT], a timed up and go test [TUG], a chest mobility test, anthropometric measures, a mobility index [Barthel], and a modified Borg scale). The collected anthropometric data and values from the 6MWT were used to create original linear models. This study followed STROBE recommendations. Results: The study group and control group did not differ statistically in terms of their anthropometric data. Statistically significant results were obtained between the first and second assessments in both groups in terms of body weight and waist circumference. However, only the study group showed improved results in the TUG test (p = 0.0001) and distance in the 6MWT (p = 0.0005). The study group presented with the normalization of blood pressure (BP) after exertion in the second assessment (systolic BP p = 0.0204; diastolic BP p = 0.0377), and the 6MWT results were close to the norms. According to the original linear model used to predict performance in the 6MWT, the primary modifiable determinant of exercise tolerance was the participant’s weight, while gender served as a non-modifiable determinant. Conclusions: Exercise-based physiotherapy in prehabilitation was associated with improved functional capacity in patients preparing for bariatric surgery, contributing to the improvement in 6MWT results in relation to the norms as well as exercise tolerance. Body weight may be an independent factor determining distance in the 6MWT for patients undergoing prehabilitation for bariatric surgery. Full article

Urban green spaces (UGS) are essential for residents’ well-being, environmental quality, and social cohesion. However, previous studies have typically employed undifferentiated analytical frameworks, overlooking UGS types and failing to adequately measure the structural disparities of different UGS types within residents’ walking distance. To address this, this study integrates Gaussian Two-Step Floating Catchment Area models, Simpson’s index, and the Gini coefficient to construct an accessibility–diversity–equality assessment framework for UGS. This study conducted an analysis of accessibility, diversity, and equity for various types of UGSs under pedestrian conditions, using the high-density city of Shenzhen, China as a case study. Results reveal high inequality in accessibility to most UGS types within 15 min to 30 min walking range, except residential green spaces, which show moderate-high inequality (Gini coefficient: 0.4–0.6). Encouragingly, UGS diversity performs well, with over 80% of residents able to access three or more UGS types within walking distance. These findings highlight the heterogeneous UGS supply and provide actionable insights for optimizing green space allocation to support healthy urban development. Full article

As dogs are often required to be leashed in public, guardians need to choose between various restraint devices. While using collars typically considered aversive (such as choke, prong, or electric collars) is generally discouraged due to welfare concerns, guidance is less clear when it comes to selecting among other devices such as collars, harnesses, and head collars. This review examined 21 full-text articles and two abstracts on the effects of commonly used restraint devices, aiming to offer practical guidance for guardians and identifying areas for future research. The impact of these devices was examined in terms of walking kinematics, pressure distribution on the body, and behavioural signs of stress. The findings suggest there is no one-size-fits-all device, and selection should consider the individual needs of guardian and dog. For dogs that pull, non-tightening front-clip harnesses appear to offer the best balance between discomfort and reduction in pulling. Tightening harnesses, martingale collars, and head collars can pose greater discomfort and should be used with caution. For brachycephalic breeds or when pulling is not a concern, back-clip harnesses are suitable, especially chest-strap or Y-shaped ones. Flat collars are also appropriate for dogs that do not pull as they produce the least body restriction. Full article

Introduction: The figure-of-eight walk test (F8WT) assesses gait on a curved path, reflecting everyday walking complexity. Despite recognized validity among elderly individuals, its application in neurological disorders remains inadequately explored. This scoping review summarizes evidence regarding F8WT use, validity, and clinical applicability among individuals with neurological disorders. Methods: A systematic literature search was conducted in the PubMed, Scopus, Embase, and Web of Science databases. After reading the full text of the selected studies and applying predefined inclusion criteria, seven studies, involving participants with multiple sclerosis (n = 3 studies), Parkinson’s disease (n = 2 studies), and stroke (n = 2 studies), were included based on pertinence and relevance to the topic. Results: F8WT demonstrated strong reliability and validity across various neurological populations and correlated significantly with established measures of gait, balance, and disease severity. Preliminary evidence supports its ability to discriminate individuals at increased fall risk and detect subtle motor performance changes. Discussion: The F8WT emerges as a valuable tool, capturing multifaceted gait impairments often missed by linear walking assessments. Sensitive to subtle functional changes, it is suitable for tracking disease progression and intervention efficacy. Conclusions: F8WT is reliable and clinically relevant, effectively identifying subtle, complex walking impairments in neurological disorders. Full article

This paper clarified the correlation among quality of life (QoL) indicators, exercise implementation level, and exercise habits in middle-aged and older adults under identical exercise intervention conditions. The survey items were anthropometric and physiologic measurements, physical strength measurements, and exercise habits. During the 3-month experimental period, a weekly “health exercise course” served as the primary intervention. For all participants, anthropometric and physiologic measurements, physical strength tests, questionnaire surveys, and other surveys were conducted before and after the experiment; then, the pre- and post-intervention effects were compared. After the exercise intervention, significant differences were observed among middle-aged and older adults in terms of various parameters, such as weight, fat rate, diastolic pressure, systolic pressure, sit-up, standing on one foot, lower limb extension force, activity of daily living (ADL), and subjective well-being (PGC). ADL and PGC changed significantly in the participants who engaged in exercise more than twice a week. However, the participants who engaged in exercise for less than twice a week showed no significant differences in any parameters except the life satisfaction (LSI) mean; the LSI increased in the “Less than twice a week” exercise group but decreased in the “More than twice a week” group. In terms of average walking time per session, the “More than 30 min” exercise group showed significant differences in ADL and PGC, whereas the “Less than 30 min” group showed significant differences only in the LSI. The influence of exercise on QoL indicators of middle-aged and older adults, under the same exercise intervention conditions, is related to their exercise habits. This study highlights the benefits of physical exercise in middle-aged and older adults, emphasizing the importance of regular and sustained exercise for this population. Furthermore, the study provides a scientific basis for improving QoL in middle-aged and older adults, thus, to some extent, addressing the concerns related to the growing population of older adults. Full article

This paper demonstrates the benefits of adapting Zero Velocity Update (ZVU) algorithms in foot-mounted pedestrian inertial navigation by finely tuning the algorithm to account for the type of terrain over which the pedestrian travels. Conventional ZVU algorithms for foot-mounted inertial navigation are designed for indoor use and do not account for differences from various terrains. Different terrains affect the natural pedestrian gait and how zero velocity intervals (ZVIs) are identified. By tuning the algorithm to account for accelerometer and gyroscope magnitude and walking cycle duration across four terrains (concrete, grass, pebbles and sand), the accuracy is improved up to 31.04%, dependent on the terrain, and is viable for outdoor use. Full article

This paper presents a novel approach to enhancing the security of error correction in quantum key distribution by introducing randomization into the update rule of Tree Parity Machines. Two dynamic update algorithms—dynamic_rows and dynamic_matrix—are proposed and tested. These algorithms select the update rule quasi-randomly based on the input vector, reducing the effectiveness of synchronization-based attacks. A series of simulations were conducted to evaluate the security implications under various configurations, including different values of K, N, and L parameters of neural networks. The results demonstrate that the proposed dynamic algorithms can significantly reduce the attacker’s synchronization success rate without requiring additional communication overhead. Both proposed solutions outperformed hebbian, an update rule-based synchronization method utilizing the percentage of attackers synchronization. It has also been shown that when the attacker chooses their update rule randomly, the dynamic approaches work better compared to random walk rule-based synchronization, and that in most cases it is more profitable to use dynamic update rules when an attacker is using random walk. This study contributes to improving QKD’s robustness by introducing adaptive neural-based error correction mechanisms. Full article

We revisit the problem of random search walks in the two-dimensional (2D) space between concentric absorbing annuli, in which a searcher performs random steps until finding either the inner or the outer ring. By considering step lengths drawn from a power-law distribution, we obtain the exact analytical result for the search efficiency $\eta$ in the ballistic limit, as well as an approximate expression for $\eta$ in the regime of searches starting far away from both rings, and the scaling behavior of $\eta$ for very small initial distances to the inner ring. Our numerical results show good overall agreement with the theoretical findings. We also analyze numerically the absorbing probabilities related to the encounter of the inner and outer rings and the associated Shannon entropy. The power-law exponent marking the crossing of such probabilities (equiprobability) and the maximum entropy condition grows logarithmically with the starting distance. Random search walks inside absorbing annuli are relevant, since they represent a mean-field approach to conventional random searches in 2D, which is still an open problem with important applications in various fields. Full article

The repurposing potential of Efavirenz (EFV), a clinically established non-nucleoside reverse transcriptase inhibitor, was comprehensively evaluated for its in vitro antibacterial effect either alone or in combination with other antibacterial agents on several Gram-positive clinical strains showing different antibiotic resistance profiles. The binding potential assessed by an in silico study included Penicillin-binding proteins (PBPs) and WalK membrane kinase. Despite the relatively high minimum inhibitory concentration (MIC) limiting the use of EFV as a single antibacterial agent, it exhibits significant synergistic activity at sub-MIC levels when paired with various antibiotics against Enterococcus species and Staphylococcus aureus. EFV showed restored sensitivity of β-lactams against Methicillin-resistant S. aureus (MRSA). It increased the effectiveness of antibiotics tested against Methicillin-sensitive S. aureus (MSSA). It also helped to overcome the intrinsic resistance barrier for several antibiotics in Enterococcus spp. In silico binding studies aligned remarkably with experimental antimicrobial testing results and highlighted the potential of EFV to direct the engagement of PBPs with moderate to strong binding affinities (pK_a 5.2–6.1). The dual-site PBP2 binding mechanism emerged as a novel inhibition strategy, potentially circumventing resistance mutations. Special attention should be paid to WalK binding predictions (pK_a = 4.94), referring to the potential of EFV to interfere with essential regulatory pathways controlling cell wall metabolism and virulence factor expression. These findings, in general, suggest the possibility of EFV as a promising lead for the development of new antibacterial agents. Full article

Gait, the fundamental form of human locomotion, occurs across diverse environments. The technology for recognizing environmental changes during walking is crucial for preventing falls and controlling wearable robots. This study collected gait data on level ground (LG), ramps, and stairs using a feed-forward neural network (FFNN) to classify the corresponding gait environments. Gait experiments were performed on five non-disabled participants using an inertial measurement unit, a galvanic skin response sensor, and a smart insole. The collected data were preprocessed through time synchronization and filtering, then labeled according to the gait environment, yielding 47,033 data samples. Gait data were used to train an FFNN model with a single hidden layer, achieving a high accuracy of 98%, with the highest accuracy observed on LG. This study confirms the effectiveness of classifying gait environments based on signals acquired from various wearable sensors during walking. In the future, these research findings may serve as basic data for exoskeleton robot control and gait analysis. Full article

Every day humans interact with smartphones that have embedded sensors that enable the tracking of changing physical activities of the device owner. However, several problems arise with the recognition of multiple activities (such as walking, sitting, running, and other) on smartphones. Firstly, most of the devices do not recognize some activities well, such as walking upstairs or downstairs. Secondly, recognition algorithms are embedded into smartphone software and are static, unless updated. In this case, a recognition algorithm must be re-trained with training data of a specific size. Thus, an adaptive (also known as, online or incremental) learning algorithm would be useful in this situation. In this work, an adaptive learning and classification algorithm based on hidden Markov models (HMMs) is applied to human activity recognition, and an architecture model for smartphones is proposed. To create a self-learning method, a technique that involves building an incremental algorithm in a maximal likelihood framework has been developed. The adaptive algorithms created enable fast self-learning of the model parameters without requiring the device to store data obtained from sensors. It also does not require sending gathered data to a server over the network for additional processing, making them autonomous and independent from outside systems. Experiments involving the modeling of various activities as separate HMMs with different numbers of states, as well as modeling several activities connected to one HMM, were performed. A public dataset called the Activity Recognition Dataset was considered for this study. To generalize the results, different performance metrics were used in the validation of the proposed algorithm. Full article