Search Results (626)

Long-span cable-supported bridges, such as cable-stayed and suspension bridges, are highly sensitive to wind-induced effects due to their flexibility, low damping, and relatively light weight. Aerodynamic analysis is therefore essential in their design and safety assessment. This study examines the aeroelastic stability of the Oued Dib cable-stayed bridge in Mila, Algeria, with emphasis on vortex shedding, galloping, torsional divergence, and classical flutter. A finite element modal analysis was carried out on a three-dimensional model to identify natural frequencies and mode shapes. A two-dimensional deck section was then analyzed using Computational Fluid Dynamics (CFD) under a steady wind flow of U = 20 m/s and varying angles of attack (AoA) from −10° to +10°. The simulations employed a RANS k-ω SST turbulence model with a wall function of Y+ = 30. The results provided detailed airflow patterns around the deck and enabled the evaluation of static aerodynamic coefficients—drag (C_D), lift (C_L), and moment (C_M)—as functions of AoA. Finally, the bridge’s aeroelastic performance was assessed against the four instabilities. The findings indicate that the Oued Dib Bridge remains stable under the design wind conditions, although fatigue due to vortex shedding requires further consideration. Full article

This work examines the colloidal properties of clays sampled from two different locations in Ventzia basin processed as low-density solid additives for water-based drilling fluid applications. The obtained samples were mechanically processed to reach a size less than 2 cm. The material was then activated with 3 wt% soda ash without oven drying, keeping the moisture in environmental conditions to simulate industrial activation conditions. After laying for one month curing time, samples were oven dried at 60 °C and further ground to <120 μm. Two groups of samples were created mixing clays from Ventzia basin and additives. The first group contained clay, xanthan gum and sodium polyacrylate (PAA), while the second group contained clay, xanthan gum and sodium hexametaphosphate (SHMP). Standard tests were performed for the rheological behavior and filtration properties prior to and after dynamic thermal aging. Results obtained were compared with commercial clays from Milos and Wyoming used in drilling fluid systems, after thermally deteriorating also their properties. The obtained results revealed that the enhanced clays under study maintain excellent thermal stability. Notably, the top-performing formulation met the critical American Petroleum Institute (API) benchmark for filtrate loss (<15 mL) and exhibited a robust rheological profile at temperatures up to 105 °C, demonstrating its suitability for water-based fluid (WBF) applications. Full article

Inspired by the free-flight capabilities of the gannet in both aerial and underwater environments, a foldable-wing air–water cross-medium vehicle was designed. To enhance its propulsive performance and transition stability across these two media, aero-hydrodynamic performance analyses were conducted under three representative operating states: aerial flight, underwater navigation, and water entry. Numerical simulations were performed in ANSYS Fluent (Version 2022R2) to quantify lift, drag, lift-to-drag ratio (L/D), and tri-axial moment responses in both air and water. The transient multiphase flow characteristics during water entry were captured using the Volume of Fluid (VOF) method. The results indicate that: (1) in the aerial state, the lift coefficient increases almost linearly with the angle of attack, and the L/D ratio peaks within the range of 4–6°; (2) in the folded (underwater) configuration, the fuselage still generates effective lift, with a maximum L/D ratio of approximately 2.67 at a 10° angle of attack; (3) transient water entry exhibits a characteristic two-stage force history (“initial impact” followed by “steady release”), with the peak vertical load increasing significantly with water entry angle and velocity. The maximum vertical force reaches 353.42 N under the 60°, 5 m/s condition, while the recommended compromise scheme of 60°, 3 m/s effectively reduces peak load and improves attitude stability. This study establishes a closed-loop analysis framework from biomimetic design to aero-hydrodynamic modeling and water entry analysis, providing the physical basis and parameter support for subsequent cross-medium attitude control, path planning, and intelligent control system development. Full article

Two HPLC-based analytical methods, one with DAD and the other with an FLD detector, were developed and validated for the simultaneous analysis of B₁, B₂, and B₆ vitamins, both in pharmaceutical gummies and in gastric and intestinal fluids (with water or milk or orange juice). For the detection of B₁ by fluorometry, a pre-column oxidation/derivatization process was accomplished in the presence of B₂ and B₆ vitamins. The methods were performed on an Aqua column (250 mm × 4.6 mm, 5 mm) at 40 °C, with isocratic elution (70% NaH₂PO₄ buffer pH 4.95 and 30% methanol) and a flow rate of 0.9 mL/min. Both were validated according to ICH specifications in terms of linearity (R² > 0.999), accuracy (% Mean Recovery 100 ± 3%) and precision (%RSD < 3.23). For the analysis of the samples, a stability study (in diluents, pH and fluids) was conducted, while for their purification two different extraction procedures, a liquid/solid for the gummies (%Recovery > 99.8%) and a Solid Phase Extraction (SPE) for the Gastrointestinal (G.I.) fluids, (%Recovery 100 ± 5%) were developed. Finally, to investigate whether the co-administration of B-complex with water, orange juice or milk plays a significant role in their release from gummies, a three-phase in vitro digestion protocol was applied. The results did not show significant differences with a slight superiority in the release of B₂ and B₆ with water, while B₁ with orange juice. Full article

Near-wall flow around circular cylinders is commonly encountered in various engineering applications, such as submarine pipelines and river-crossing conduits. The wake structure significantly influences local flow stability and has become a critical focus in fluid dynamics research. Specifically, when the gap ratio (G/D) ranges from 0.1 to 1.0, the interaction mechanism between the wall and the wake structure remains poorly understood. Moreover, the combined effects of the Reynolds number (Re) and gap ratio on the flow field require further investigation. In this study, a series of experimental measurements were conducted using two-dimensional, two-component particle image velocimetry (2D–2C PIV) to examine the influence of G/D and Re on the near-wall wake characteristics. The results indicate that, at a gap ratio of G/D = 0.1, the gap flow exhibits pronounced curling into the recirculation region, where the lower vortex is entrained and actively participates in wake evolution. When G/D ≥ 0.3, an increase in Re leads to a reduction in the lengths of both the upper and lower shear layers, a delayed attenuation of the wall-side shear layer, and a gradual symmetrization and contraction of the recirculation region behind the cylinder. Further analysis reveals that the evolution of the secondary vortex is strongly influenced by the combined effects of Re and G/D. Specifically, at Re = 3300 and G/D ≤ 0.3, the secondary vortex migrates away from the wall toward the upper shear layer, where it merges with the upper vortex. For 0.5 ≤ G/D ≤ 0.7, it interacts with the lower vortex, while at G/D = 1.0, it evolves independently downstream along the wall. At G/D = 0.5, the secondary vortex merges with the upper vortex at Re = 1100, whereas at Re = 5500, it interacts with the lower vortex instead. These findings contribute to a deeper understanding of the complex flow structures associated with near-wall cylinder wakes and offer valuable theoretical insights for engineering applications involving submarine pipelines in bottom-mounted or partially suspended configurations. Full article

As a core component of aero-engines, double-row ball bearings’ lubrication performance directly impacts the operational stability of the aircraft engine. However, existing under-race lubrication designs primarily rely on empirical knowledge, with insufficient understanding of the complex oil–air two-phase flow mechanisms, leading to bottlenecks in optimizing lubrication efficiency. Therefore, based on the computational fluid dynamics (CFD) method, a two-phase flow model for double-row ball bearings was established to systematically analyze the influence patterns of key parameters—including rotational speed, oil supply rate, number of under-race holes, diameter of under-race holes, and oil properties (viscosity, density)—on the distribution of the oil–air two-phase flow. The findings reveal that (1) the oil in the circumferential direction of the bearing cavity exhibits periodic distribution characteristics correlated with the number of under-race holes; (2) the self-rotation effect of balls hinders the migration of oil toward the outer raceway region, resulting in a significant reduction in the oil volume fraction within the bearing cavity; (3) compared with the single-sided oil supply configuration, the double-sided oil supply structure demonstrates superior lubrication performance. These research results provide theoretical support and reference data for the optimal design of under-race lubrication systems for double-row ball bearings. Full article

This study evaluates ground mandarin peel (MP) as a low-cost modifier for sodium-bentonite water-based drilling fluids. Formulations with 2% (w/w) MP and 1–4% bentonite were prepared to locate the composition break point using segmented regression with the Davies test; the threshold was 2.5% bentonite (B/MP ≈ 1.25). Below this level, yield stress drops sharply, and American Petroleum Institute (API) fluid loss increases nonlinearly. Two 3% bentonite muds were then compared: a polymer-stabilized reference (0.3% xanthan gum (XCD), 1% low-viscosity carboxymethyl cellulose (CMC LV), 1% modified starch) and the same package plus 2% MP. Twelve-speed rheometry and API tests showed that adding MP left plastic viscosity essentially unchanged, increased yield stress to ~3.4 Pa, reduced API fluid loss from 9 to 5.5 mL per 30 min, and thinned the filter cake from 0.30 to 0.10 mm. Because MP is a zero-price waste stream, material cost remained essentially unchanged while performance improved. These results support a practical dosing window for MP and a polymer adjustment pathway; high temperature and high-salinity stability require further verification. Full article

Composite breakwater is a commonly employed structure for coastal and harbor protection. However, strong hydrodynamic impact can lead to failure and instability of these protective structures. In this study, a two-dimensional fluid-porous-solid coupling model is developed to investigate the stability of composite breakwaters. The fluid-porous model is based on the Volume-Averaged Reynolds-Averaged Navier-Stokes equations, in which the nonlinear Forchheimer equations are added to describe the porous layer. The solid model employs the Nodal-based Discontinuous Deformation Analysis (NDDA) method to analyze the displacement of the caisson. NDDA is a nodal-based method that couples FEM and DDA to improve non-linear processes. This proposed coupled model permits the examination of the influence of the thickness and porosity of the porous layer on maximum impacting wave height (${\mathrm{IWH}}_{\max }$) and the turbulent kinetic energy (TKE) generation. The results show that high porosity values lead to the dissipation of TKE and reduce the ${\mathrm{IWH}}_{\max }$. However, the reduction in the ${\mathrm{IWH}}_{\max }$ is not monotonic with increasing porous layer thickness. We observed that ${\mathrm{IWH}}_{\max }$ reaches an optimum value as the porous layer thickness continues to increase. These results can contribute to improve the design of composite breakwaters. Full article

Control valves are widely applied in nuclear power, offshore oil/gas extraction, and chemical engineering, but suffer from issues like pressure oscillation, flow control accuracy degradation, and motor overload due to unstable fluid loads (e.g., nuclear reactions in power plants and complex marine climates). This paper proposes a dual-motor redundant compensation method to address these challenges. The core lies in a control strategy where a single main motor drives the valve under normal conditions, while a redundant motor intervenes when load torque exceeds a preset threshold—calculated via the valve core’s fluid load model. By introducing excess load torque as positive feedback to the current loop, the method coordinates torque output between the two motors. AMESim and Matlab/Simulink joint simulations compare single-motor non-compensation, single-motor compensation, and dual-motor schemes. Results show that under inlet pressure step changes, the dual-motor compensation scheme shortens the stabilization time of the valve’s controlled variable by 40%, reduces overshoot by 65%, and decreases motor torque fluctuation by 50%. This redundant design enhances fault tolerance, providing a novel approach for reliability enhancement of deep-sea oil/gas control valves. Full article

Conventional underwater vehicles, which are typically equipped with oscillating fins or standard propellers, are incapable of effective locomotion within the viscous, high-resistance environment of muddy substrates common in agricultural ponds. To address this operational limitation, this paper presents a compact dual-screw propelled robot capable of traversing both the water column and soft substrate layers. The robot’s locomotion is driven by two optimized helical screw propellers, while depth control and roll stability are actively managed by a control fin. A dynamic model of the robot–fluid interaction was developed to optimize the screw configuration that achieves a maximum theoretical thrust of 40 N with a calculated 16% slippage rate in mud. Computational fluid dynamics simulations were employed to determine the optimal angle for the control fin, which was found to be 9°, maximizing the lift-to-drag ratio at 12.09 for efficient depth maneuvering. A cable-free remote control system with a response time of less than 0.5 s governs all operations. Experimental validation in a controlled tank environment confirmed the robot’s performance, demonstrating stable locomotion at 0.4 m/s in water and 0.3 m/s in a simulated mud substrate. This dual-screw propelled robot represents a promising technological solution for comprehensive monitoring and operational tasks in agricultural pond environments. Full article

Encapsulation of fish oil within oleogels can potentially prevent oxidation and enable its use in food with programmable release within the gastrointestinal tract. Here, we report on the formation of oleogels from two different fish oils—salmon oil (SO) and cod liver oil (CLO)—using different concentrations of either rice bran wax (RBW) or myristic acid (MA) as gelators. The gels were assessed with respect to their structural, thermal, viscosity, digestive, and oxidative properties. Polarized light microscopy (POM) revealed that RBW consistently produced dense, interconnected crystalline networks across both oils, while MA formed larger, spherulitic crystals that were more sensitive to the oil type. This was further supported by time-lapse imaging, showing faster crystal growth of MA in cod liver oil. Viscosity studies indicate that the molecular weight and concentration of gelator, as well as the type of fish oil (SO vs. CLO), significantly impact the shear stability of the oleogels. Thermal and viscosity analyses confirmed that RBW-based oleogels exhibited higher crystallization temperatures and stronger viscoelastic behaviour. Based on oxidative stability measurements—as measured by peroxide value (PV) analysis—encapsulation within oleogels does not lead to significant oxidation of the fish oils and also attenuates further oxidation upon storage. The fish oil oleogels were stable when exposed to either simulated gastric or intestinal fluids (SGF and SIF, respectively), but decomposed after sequential exposure first to SGF and then to SIF. These findings could broaden the range of food products which can be fortified with fish oils. Full article

Understanding the interaction between submerged water jets and cohesive deep-sea sediment is critical for optimizing deep-sea polymetallic nodule hydraulic mining techniques. This research investigated the distinct erosion behavior of cohesive sediments through laboratory experiments and numerical simulations. Cohesive deep-sea sediments were simulated using bentonite–kaolinite mixtures. A series of laboratory experiments, including vane shear tests and viscosity tests under varying moisture content, were conducted to assess the sediments’ mechanical properties. Experimental submerged water jet erosion tests provided basic data for validating the numerical simulations. A Eulerian multi-fluid (EMF) model was implemented to capture sediment–water jet interactions under varying operational parameters, including jet velocities and nozzle heights. The erosion process was found to comprise three distinct stages, including rapid erosion, steady erosion, and stabilization. Two distinct erosion mechanisms were identified, depending on the jet intensity, which affected the depth and shape of the erosion pits. Quantitative analysis revealed that erosion depth exhibits an approximately linear relationship with jet velocity and nozzle height, whereas the erosion diameter shows nonlinear characteristics. These findings enhance the fundamental understanding of cohesive sediment responses under hydraulic disturbances, providing crucial insights for the design and optimization of efficient deep-sea mining systems. Full article

Proteins that span cellular membranes represent around 30% of the proteome and over 50% of drug targets. A variety of synthetic and naturally-occurring small organic molecules interact with membrane proteins and up- and down-regulate protein function. The atomic details of these regulatory molecules offer important information about protein function and aid the discovery, refinement and optimization of new drugs. X-ray crystallography and cryo-electron microscopy (cryo-EM) are not always able to resolve the structures of small molecules in their physiological sites on membrane proteins, particularly if the molecules are unstable or are reactive enzyme substrates. Solid-state nuclear magnetic resonance (SSNMR) is a valuable technique for filling in missing details on the conformations, dynamics and binding environments of small molecules regulators of membrane proteins. SSNMR does not require diffracting crystals possessing long-range order and can be performed on proteins within their native membranes and with freeze-trapping to maintain sample stability. Here, work over the last two decades is described, in which SSNMR methods have been developed to report on interactions of the ATP substrate with the Na,K-ATPase (NKA), an ion-transporting enzyme that maintains cellular potential in all animals. It is shown how a combination of SSNMR measurements on membranous NKA preparations in the frozen and fluid states have provided unique information about the molecular conformation and local environment of ATP in the high-affinity nucleotide site. A combination of chemical shift analysis using density functional theory (DFT) calculations, dipolar coupling measurements using REDOR and measurements of the rates of proton spin diffusion is appraised collectively. The work described herein highlights the methods developed and challenges encountered, which have led to a detailed and unrivalled picture of ATP in its high-affinity binding site. Full article

Acute transverse myelitis (ATM) is a rare, immune-mediated disorder of the spinal cord characterized by sensory, motor, and autonomic dysfunction. Although the human papillomavirus (HPV) vaccine is widely regarded as safe, isolated reports have suggested a potential temporal association with autoimmune neurological events, including ATM. We present a case of a 21-year-old woman who developed ATM two weeks following administration of the first dose of the HPV vaccine (Cervarix). The clinical presentation included rapid-onset paraparesis, sensory deficits, and sphincter dysfunction. An MRI revealed a T2-hyperintense lesion at the Th10–Th12 level. A cerebrospinal fluid analysis showed elevated protein levels. The patient underwent corticosteroid therapy, plasmapheresis, and IVIG, followed by a comprehensive, individualized rehabilitation program. This included balance and stability training, Redcord-based neuromuscular activation, electrostimulation, and pelvic floor therapy. Although no causal link between HPV vaccination and ATM has been established, this case emphasizes the importance of considering post-vaccinal autoimmune phenomena. More importantly, it illustrates the critical role of early, targeted rehabilitation—particularly pelvic floor re-education and neuromodulation—in improving outcomes in patients with significant motor and autonomic deficits. Full article

A methane-air premixed gas explosion is one of the most destructive disasters in the process of coal mining, and the dynamic coupling between the shock wave triggered by the explosion and the surrounding rock of the roadway can lead to the destabilization of the surrounding rock structure, the destruction of equipment, and casualties. The aim of this study is to systematically reveal the propagation characteristics of the blast wave, the spatial and temporal evolution of the wall load, and the damage mechanism of the surrounding rock by establishing a two-way fluid-solid coupling numerical model. Based on the Ansys Fluent fluid solver and Transient Structure module, a framework for the co-simulation of the fluid and solid domains has been constructed by adopting the standard $k-\epsilon$ turbulence model, finite-rate/eddy-dissipation (FR/ED) reaction model, and nonlinear finite-element theory, and by introducing a dynamic damage threshold criterion based on the Drucker–Prager and Mohr–Coulomb criteria. It is shown that methane concentration significantly affects the kinetic behavior of explosive shock wave propagation. Under chemical equivalence ratio conditions (9.5% methane), an ideal Chapman–Jouguet blast wave structure was formed, exhibiting the highest energy release efficiency. In contrast, lean ignition (7%) and rich ignition (12%) conditions resulted in lower efficiencies due to incomplete combustion or complex combustion patterns. In addition, the pressure time-history evolution of the tunnel enclosure wall after ignition triggering exhibits significant nonlinear dynamics, which can be divided into three phases: the initiation and turbulence development phase, the quasi-steady propagation phase, and the expansion and dissipation phase. Further analysis reveals that the closed end produces significant stress aggregation due to the interference of multiple reflected waves, while the open end increases the stress fluctuation due to turbulence effects. The spatial and temporal evolution of the strain field also follows a three-stage dynamic pattern: an initial strain-induced stage, a strain accumulation propagation stage, and a residual strain stabilization stage and the displacement is characterized by an initial phase of concentration followed by gradual expansion. This study not only deepens the understanding of methane-air premixed gas explosion and its interaction with the roadway’s surrounding rock, but also provides an important scientific basis and technical support for coal mine safety production. Full article