Numerical time series data are pervasive, originating from sources as diverse as wearable devices, medical equipment, to sensors in industrial plants. In many cases, time series contain interesting information in terms of subsequences that recur in a...
As the availability of big data-sets becomes more widespread so the importance of motif (or repeated pattern) identification and analysis increases. To date, the majority of motif identification algorithms that permit flexibility of sub-sequence leng...
The Matrix Profile (MP) algorithm has the potential to revolutionise many areas of data analysis. In this article, several applications to financial time series are examined. Several approaches for the identification of similar behaviour patterns (or...
A common challenge in multimedia data understanding is the unsupervised discovery of recurring patterns, or motifs, in time series data. The discovery of motifs in uni-variate time series is a well studied problem and, while being a relatively new ar...
We introduce simplicial persistence, a measure of time evolution of motifs in networks obtained from correlation filtering. We observe long memory in the evolution of structures, with a two power law decay regimes in the number of persistent simplici...
The phenomenon of big data has occurred in many fields of knowledge, one of which is astronomy. One example of a large dataset in astronomy is that of numerically integrated time series asteroid orbital elements from a time span of millions to billio...
Currently, big sensor data arise in a wide spectrum of Industry 4.0, Internet of Things, and Smart City applications. In such subject domains, sensors tend to have a high frequency and produce massive time series in a relatively short time interval....
Sleep disorders pose serious cardiovascular threats if not treated effectively. However, adherence to Continuous Positive Airway Pressure (CPAP), the most recommended therapy, is known to be challenging to monitor. Telemonitored CPAP equipment has im...
Capturing long-term statistics of signals and time series is important for modeling recurrent phenomena, especially when such recurrences are a-periodic and can be characterized by the approximate repetition of variable length motifs, such as pattern...
Summarization of a long time series often occurs in analytical applications related to decision-making, modeling, planning, and so on. Informally, summarization aims at discovering a small-sized set of typical patterns (subsequences) to briefly repre...
In this paper, we describe the supervised dynamic correlated topic model (sDCTM) for classifying categorical time series. This model extends the correlated topic model used for analyzing textual documents to a supervised framework that features dynam...
The reversible and substoichiometric modification of RNA has recently emerged as an additional layer of translational regulation in normal biological function and disease. Modifications are often enzymatically deposited in and removed from short (~5...
Benzimidazoles are classified as a category of heterocyclic compounds. Molecules having benzimidazole motifs show promising utility in organic and scientific studies. A series of mono-substituted benzimidazoles were synthesized by ZnO-NPs via cycloco...
A systematic density functional theory (DFT) and time-dependent DFT (TD-DFT) investigation of aluminum phosphide (AlxPx) nanoparticles with diverse dimensionalities and geometries is presented. Starting from a cubic-like Al4P4 building block, a serie...
Increasing both the sensitivity and selectivity of thiol-functionalized gold nanoparticle chemiresistors remains a challenging issue in the quest to develop real-time gas sensors. The effects of thiol molecular structure on such sensor properties are...
In this work, the design and synthesis of a series of photochromic gemini diarylethene-based ionic liquids (GDILs) with different cationic motifs is reported. Several synthetic pathways were optimized for the formation of cationic GDILs with chloride...
Numerous pan-genomic studies identified alterations in protein-coding genes and signaling pathways involved in bladder carcinogenesis, while non-coding somatic alterations remain weakly explored. The goal of this study was to identify clinical biomar...
In this paper, we present and benchmark FilterNet, a flexible deep learning architecture for time series classification tasks, such as activity recognition via multichannel sensor data. It adapts popular convolutional neural network (CNN) and long sh...
A series of 1,3,5-triazine derivatives, incorporating aminobenzenesulfonamide, aminoalcohol/phenol, piperazine, chalcone, or stilbene structural motifs, were evaluated as potential antioxidants. The compounds were prepared by using step by step nucle...
The transdisciplinary nature of science as a whole became evident as the necessity for the complex nature of phenomena to explain social and life science, along with the physical sciences, blossomed into complexity theory and most recently into compl...
We designed and synthesized helical short oligopeptides with an l-proline on the N-terminus and hydrocarbon stapling on the side chain. Side-chain stapling is a frequently used method for the development of biologically active peptides. Side-chain st...
Histidine and cysteine residues, with their imidazole and thiol moieties that deprotonate at approximately physiological pH values, are primary binding sites for Zn(II), Ni(II) and Fe(II) ions and are thus ubiquitous both in peptidic metallophores an...
NF-YB, a subfamily of Nuclear Factor Y (NF-Y) transcription factor, play crucial role in many biological processes of plant growth and development and abiotic stress responses, and they can therefore be good candidate factors for breeding stress-resi...
To develop peptide drugs targeting integrin receptors, synthetic peptide ligands endowed with well-defined selective binding motifs are necessary. The snake venom KTS-containing disintegrins, which selectively block collagen α1β1 integrin, were used...
A series of Schiff bases, salicylideneaniline derivatives 1–4, was synthesized under mild conditions and characterized by 1H NMR, HRMS, UV-Vis and fluorescence spectra, and single-crystal X-ray diffraction. In solid and aprotic solvents 1–4 exist mai...
Biochemical networks having similar functional pathways are often correlated due to cross-talk among the homologous proteins in the different networks. Using a stochastic framework, we address the functional significance of the cross-talk between two...
The crucial feature of organoselenium compounds, when considering them as promising drug candidates in cancer therapy, is their unique ability to alter the cellular redox regulations. Organic Se-molecules continue to demonstrate a positive therapeuti...
A series of 1,3,5-triazine analogues, incorporating aminobenzene sulfonamide, aminoalcohol/phenol, piperazine, chalcone, or stilbene structural motifs, were evaluated as potential antioxidants. The compounds were prepared by using step-by-step nucleo...
Harmonic emissions cause power quality issues in electrical systems, making source identification necessary to determine the best way of remedying them. Existing methods rely on measuring variations in harmonic amplitude, angle, and phase which requi...
Plant protease inhibitors are a ubiquitous feature of plant species and exert a substantial influence on plant stress responses. However, the KTI (Kunitz trypsin inhibitor) family responding to abiotic stress has not been fully characterized in Popul...
Nuclear movements during meiotic prophase, driven by cytoskeleton forces, are a broadly conserved mechanism in opisthokonts and plants to promote pairing between homologous chromosomes. These forces are transmitted to the chromosomes by specific asso...
The Enterovirus genus includes many viruses that are pathogenic in humans, including Coxsackie viruses and rhinoviruses, as well as the emerging enteroviruses D68 and A71. Currently, effective antiviral agents are not available for the treatment or p...
The detection and deterrence of collusive agreements among firms, such as price-fixing cartels, remain pivotal in maintaining market competition. This study investigates the application of machine learning methodologies in the behavioral screening pr...
To date, certain problems have been identified in cancer immunotherapy using the inhibition of immune checkpoints (ICs). Despite the excellent effect of cancer therapy in some cases when blocking the PD-L1 (programmed death-ligand 1) ligand and the i...
Lignin is an important biological polymer in plants that is necessary for plant secondary cell wall ontogenesis. The laccase (LAC) gene family catalyzes lignification and has been suggested to play a vital role in the plant kingdom. In this study, we...
Mycobacterium tuberculosis (Mtb) serine/threonine (Ser/Thr) Protein kinases A (PknA) and B (PknB) have been identified as highly attractive targets for overcoming drug resistant tuberculosis. A recent lead series optimization study yielded compound 3...
‘Huangguan’ pear (Pyrus bretschneideri Rehd) fruit is susceptible to cold, characterized by developing peel browning spots (PBS) during cold storage. Additionally, ethylene pretreatment reduces chilling injury (CI) and inhibits PBS occurr...
Lotus (Nelumbo nucifera Gaertn.) is a traditional Chinese aquatic flower with high ornamental and economic value, but water salinity seriously affects lotus cultivation and distribution. The Dof transcription factors (TFs) play a crucial function in...
Lactobacillus paracasei K5 is a lactic acid bacteria (LAB) strain that has been isolated from dairy products. Previous studies have established its probiotic potential in a series of in vitro tests, including molecular characterization, safety profil...
The utilization of plug-in electric vehicles (PEV) has started to garner more attention worldwide considering the environmental and economic benefits. This has led to the invention of new technologies and motifs associated with batteries, bidirection...
α-Conotoxins GI and MI belong to the 3/5 subfamily of α-conotoxins and potently inhibit muscular nicotinic acetylcholine receptors (nAChRs). To date, no 3/4- or 3/6-subfamily α-conotoxins have been reported to inhibit muscular nAChRs. In the present...
A series of four Werner-type complexes of Pd(II) and Pt(II) with planar, isomeric conjugated aromatic naphtoquinone oximes were synthesized for the first time. These ligands were 1-oxime-2-naphtoquinone (HL1) and 2-oxime-1-napthoquinone (HL2). Compou...
Heat shock protein 20 (Hsp20) is a major family of heat shock proteins that mainly function as molecular chaperones and are markedly accumulated in cells when organisms are subjected to environmental stress, particularly heat. Canavalia rosea is an e...
Background: Severe coronavirus disease 2019 (COVID-19) disease courses are characterized by immuno-inflammatory, thrombotic, and parenchymal alterations. Prediction of individual COVID-19 disease courses to guide targeted prevention remains challengi...
Background: Hepatocellular carcinoma remains a global health challenge with high mortality rates. The tumor immune microenvironment significantly impacts disease progression and survival. However, traditional analyses predominantly focus on single im...
Carbon footprint reduction issues have been drawing more and more attention these days. Reducing the energy consumption is among the basic directions along this line. In the paper, a low-energy approach to tsunami danger evaluation is concerned. Afte...