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Keywords = supply chain network configuration

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21 pages, 1577 KB  
Article
Copper Closed-Loop Supply Chain Network Design Based on a Two-Stage Stochastic Programming Model Considering Uncertain Market Prices
by Mou Shen, Ying Guo, Hui Gao and Hongtao Ren
Sustainability 2025, 17(20), 8977; https://doi.org/10.3390/su17208977 - 10 Oct 2025
Viewed by 744
Abstract
Copper is a critically important metal for economic security, and its supply chain is influenced by various factors, particularly market prices. This paper aims to uncover the impact of high uncertainty in copper prices on the copper supply chain (CSC) configuration and propose [...] Read more.
Copper is a critically important metal for economic security, and its supply chain is influenced by various factors, particularly market prices. This paper aims to uncover the impact of high uncertainty in copper prices on the copper supply chain (CSC) configuration and propose strategies for CSC construction. To achieve this goal, this study presents a closed-loop supply chain (CLSC) network, simulates copper market volatility using the geometric Brownian motion (GBM) model, and establishes a two-stage stochastic programming (TSSP) model. An empirical study was conducted using geographical and economic data of the CSC in the Chinese province of Hunan. The research results indicate that there is a threshold in copper prices that can lead to the construction of a reverse supply chain (RSC). However, significant fluctuations in copper prices introduce uncertainty into the supply chain network configuration. Therefore, policy measures to encourage copper scrap recycling should be implemented to maintain the safety of the CLSC during market instability. The proposed modelling framework for addressing fluctuation factors in supply chain design has been validated and can be promoted to other similar industries affected by markets. Full article
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37 pages, 1013 KB  
Article
Quantum–Classical Optimization for Efficient Genomic Data Transmission
by Ismael Soto, Verónica García and Pablo Palacios Játiva
Mathematics 2025, 13(17), 2792; https://doi.org/10.3390/math13172792 - 30 Aug 2025
Viewed by 849
Abstract
This paper presents a hybrid computational architecture for efficient and robust digital transmission inspired by helical genetic structures. The proposed system integrates advanced modulation schemes, such as multi-pulse-position modulation (MPPM), high-order quadrature amplitude modulation (QAM), and chirp spread spectrum (CSS), along with Reed–Solomon [...] Read more.
This paper presents a hybrid computational architecture for efficient and robust digital transmission inspired by helical genetic structures. The proposed system integrates advanced modulation schemes, such as multi-pulse-position modulation (MPPM), high-order quadrature amplitude modulation (QAM), and chirp spread spectrum (CSS), along with Reed–Solomon error correction and quantum-assisted search, to optimize performance in noisy and non-line-of-sight (NLOS) optical environments, including VLC channels modeled with log-normal fading. Through mathematical modeling and simulation, we demonstrate that the number of helical transmissions required for genome-scale data can be drastically reduced—up to 95% when using parallel strands and high-order modulation. The trade-off between redundancy, spectral efficiency, and error resilience is quantified across several configurations. Furthermore, we compare classical genetic algorithms and Grover’s quantum search algorithm, highlighting the potential of quantum computing in accelerating decision-making and data encoding. These results contribute to the field of operations research and supply chain communication by offering a scalable, energy-efficient framework for data transmission in distributed systems, such as logistics networks, smart sensing platforms, and industrial monitoring systems. The proposed architecture aligns with the goals of advanced computational modeling and optimization in engineering and operations management. Full article
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40 pages, 7084 KB  
Article
Cascading Failure Modeling and Resilience Analysis of Coupled Centralized Supply Chain Networks Under Hybrid Loads
by Ziqiang Zeng, Ning Wang, Dongyu Xu and Rui Chen
Systems 2025, 13(9), 729; https://doi.org/10.3390/systems13090729 - 22 Aug 2025
Cited by 3 | Viewed by 2434
Abstract
As manufacturing and logistics-oriented supply chains continue to expand in scale and complexity, and the coupling between their physical execution layers and information–decision layers deepens, the resulting high interdependence within the system significantly increases overall fragility. Driven by key technological barriers, economies of [...] Read more.
As manufacturing and logistics-oriented supply chains continue to expand in scale and complexity, and the coupling between their physical execution layers and information–decision layers deepens, the resulting high interdependence within the system significantly increases overall fragility. Driven by key technological barriers, economies of scale, and the trend toward resource centralization, supply chains have increasingly evolved into centralized structures, with critical functions such as decision-making highly concentrated in a few focal firms. While this configuration may enhance coordination under normal conditions, it also significantly increases dependency on focal nodes. Once a focal node is disrupted, the intense task, information, and risk loads it carries cannot be effectively dispersed across the network, thereby amplifying load spillovers, coordination imbalances, and information delays, and ultimately triggering large-scale cascading failures. To capture this phenomenon, this study develops a coupled network model comprising a Physical Network and an Information and Decision Risk Network. The Physical Network incorporates a tri-load coordination mechanism that distinguishes among theoretical operational load (capacity), actual production load (production output), and actual delivery load (order fulfillment), using a load sensitivity coefficient to describe the asymmetric propagation among them. The Information and Decision Risk Network is further divided into a communication subnetwork, which represents transmission efficiency and delay, and a decision risk subnetwork, which reflects the diffusion of uncertainty and risk contagion caused by information delays. A discrete-event simulation approach is employed to evaluate system resilience under various failure modes and parametric conditions. The results reveal the following: (1) under a centralized structure, poorly allocated redundancy can worsen local imbalances and amplify disruptions; (2) the failure of a focal firm is more likely to cause a full network collapse; and (3) node failures in the Communication System Network have a greater destabilizing effect than those in the Physical Network. Full article
(This article belongs to the Section Complex Systems and Cybernetics)
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27 pages, 654 KB  
Article
The Interplay of Network Architecture and Performance in Supply Chains: A Multi-Tier Analysis of Visible and Invisible Ties
by Myung Kyo Kim and Tobias Schoenherr
Processes 2025, 13(8), 2571; https://doi.org/10.3390/pr13082571 - 14 Aug 2025
Cited by 1 | Viewed by 1349
Abstract
While supply chain competition increasingly occurs at the network level, most research remains limited to dyadic or triadic relationships, failing to capture the full complexity of multi-tier supply networks. This research investigates the influence of four distinct types of network ties—contractual, transactional, professional, [...] Read more.
While supply chain competition increasingly occurs at the network level, most research remains limited to dyadic or triadic relationships, failing to capture the full complexity of multi-tier supply networks. This research investigates the influence of four distinct types of network ties—contractual, transactional, professional, and personal—on supply chain performance, evaluated across five dimensions: cost, quality, delivery, flexibility, and innovation. The analysis draws on data gathered from 153 component-level supply networks, encompassing a total of 1852 entities within South Korea’s automotive and electronics manufacturing sectors. We employed social network analysis with a directed-valued network approach to capture asymmetric relationships. Results reveal that network architecture affects performance dimensions differently: centralized professional knowledge sharing enhances delivery performance, while concentrated personal ties prove detrimental; for innovation, dense network connections and dominant transactional hubs unexpectedly hinder performance by fostering conformity; cost performance shows mixed effects, with transactional centralization impeding efficiency while professional and personal leadership facilitates cost reduction. The influence of the original equipment manufacturer on supplier selection moderates these relationships, particularly mitigating negative impacts of personal tie centralization. These findings challenge conventional assumptions about network density benefits and demonstrate that supply network competence—the ability to configure and leverage network architecture—requires careful consideration of multiple tie types and their distinct effects on different performance outcomes. Full article
(This article belongs to the Special Issue Innovation and Optimization of Production Processes in Industry 4.0)
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21 pages, 1369 KB  
Article
Optimizing Cold Food Supply Chains for Enhanced Food Availability Under Climate Variability
by David Hernandez-Cuellar, Krystel K. Castillo-Villar and Fernando Rey Castillo-Villar
Foods 2025, 14(15), 2725; https://doi.org/10.3390/foods14152725 - 4 Aug 2025
Viewed by 1481
Abstract
Produce supply chains play a critical role in ensuring fruits and vegetables reach consumers efficiently, affordably, and at optimal freshness. In recent decades, hub-and-spoke network models have emerged as valuable tools for optimizing sustainable cold food supply chains. Traditional optimization efforts typically focus [...] Read more.
Produce supply chains play a critical role in ensuring fruits and vegetables reach consumers efficiently, affordably, and at optimal freshness. In recent decades, hub-and-spoke network models have emerged as valuable tools for optimizing sustainable cold food supply chains. Traditional optimization efforts typically focus on removing inefficiencies, minimizing lead times, refining inventory management, strengthening supplier relationships, and leveraging technological advancements for better visibility and control. However, the majority of models rely on deterministic approaches that overlook the inherent uncertainties of crop yields, which are further intensified by climate variability. Rising atmospheric CO2 concentrations, along with shifting temperature patterns and extreme weather events, have a substantial effect on crop productivity and availability. Such uncertainties can prompt distributors to seek alternative sources, increasing costs due to supply chain reconfiguration. This research introduces a stochastic hub-and-spoke network optimization model specifically designed to minimize transportation expenses by determining optimal distribution routes that explicitly account for climate variability effects on crop yields. A use case involving a cold food supply chain (CFSC) was carried out using several weather scenarios based on climate models and real soil data for California. Strawberries were selected as a representative crop, given California’s leading role in strawberry production. Simulation results show that scenarios characterized by increased rainfall during growing seasons result in increased yields, allowing distributors to reduce transportation costs by sourcing from nearby farms. Conversely, scenarios with reduced rainfall and lower yields require sourcing from more distant locations, thereby increasing transportation costs. Nonetheless, supply chain configurations may vary depending on the choice of climate models or weather prediction sources, highlighting the importance of regularly updating scenario inputs to ensure robust planning. This tool aids decision-making by planning climate-resilient supply chains, enhancing preparedness and responsiveness to future climate-related disruptions. Full article
(This article belongs to the Special Issue Climate Change and Emerging Food Safety Challenges)
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33 pages, 3561 KB  
Article
A Robust Analytical Network Process for Biocomposites Supply Chain Design: Integrating Sustainability Dimensions into Feedstock Pre-Processing Decisions
by Niloofar Akbarian-Saravi, Taraneh Sowlati and Abbas S. Milani
Sustainability 2025, 17(15), 7004; https://doi.org/10.3390/su17157004 - 1 Aug 2025
Cited by 1 | Viewed by 915
Abstract
Natural fiber-based biocomposites are rapidly gaining traction in sustainable manufacturing. However, their supply chain (SC) designs at the feedstock pre-processing stage often lack robust multicriteria decision-making evaluations, which can impact downstream processes and final product quality. This case study proposes a sustainability-driven multicriteria [...] Read more.
Natural fiber-based biocomposites are rapidly gaining traction in sustainable manufacturing. However, their supply chain (SC) designs at the feedstock pre-processing stage often lack robust multicriteria decision-making evaluations, which can impact downstream processes and final product quality. This case study proposes a sustainability-driven multicriteria decision-making framework for selecting pre-processing equipment configurations within a hemp-based biocomposite SC. Using a cradle-to-gate system boundary, four alternative configurations combining balers (square vs. round) and hammer mills (full-screen vs. half-screen) are evaluated. The analytical network process (ANP) model is used to evaluate alternative SC configurations while capturing the interdependencies among environmental, economic, social, and technical sustainability criteria. These criteria are further refined with the inclusion of sub-criteria, resulting in a list of 11 key performance indicators (KPIs). To evaluate ranking robustness, a non-linear programming (NLP)-based sensitivity model is developed, which minimizes the weight perturbations required to trigger rank reversals, using an IPOPT solver. The results indicated that the Half-Round setup provides the most balanced sustainability performance, while Full-Square performs best in economic and environmental terms but ranks lower socially and technically. Also, the ranking was most sensitive to the weight of the system reliability and product quality criteria, with up to a 100% shift being required to change the top choice under the ANP model, indicating strong robustness. Overall, the proposed framework enables decision-makers to incorporate uncertainty, interdependencies, and sustainability-related KPIs into the early-stage SC design of bio-based composite materials. Full article
(This article belongs to the Special Issue Sustainable Enterprise Operation and Supply Chain Management)
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33 pages, 1238 KB  
Article
Crisis Response Modes in Collaborative Business Ecosystems: A Mathematical Framework from Plasticity to Antifragility
by Javaneh Ramezani, Luis Gomes and Paula Graça
Mathematics 2025, 13(15), 2421; https://doi.org/10.3390/math13152421 - 27 Jul 2025
Viewed by 1358
Abstract
Collaborative business ecosystems (CBEs) are increasingly exposed to disruptive events (e.g., pandemics, supply chain breakdowns, cyberattacks) that challenge organizational adaptability and value creation. Traditional approaches to resilience and robustness often fail to capture the full range of systemic responses. This study introduces a [...] Read more.
Collaborative business ecosystems (CBEs) are increasingly exposed to disruptive events (e.g., pandemics, supply chain breakdowns, cyberattacks) that challenge organizational adaptability and value creation. Traditional approaches to resilience and robustness often fail to capture the full range of systemic responses. This study introduces a unified mathematical framework to evaluate four crisis response modes—plasticity, resilience, transformative resilience, and antifragility—within complex adaptive networks. Grounded in complex systems and collaborative network theory, our model formalizes both internal organizational capabilities (e.g., adaptability, learning, innovation, structural flexibility) and strategic interventions (e.g., optionality, buffering, information sharing, fault-injection protocols), linking them to pre- and post-crisis performance via dynamic adjustment functions. A composite performance score is defined across four dimensions (Innovation, Contribution, Prestige, and Responsiveness to Business Opportunities), using capability–strategy interaction matrices, weighted performance change functions, and structural transformation modifiers. The sensitivity analysis and scenario simulations enable a comparative evaluation of organizational configurations, strategy impacts, and phase-transition thresholds under crisis. This indicator-based formulation provides a quantitative bridge between resilience theory and practice, facilitating evidence-based crisis management in networked business environments. Full article
(This article belongs to the Special Issue Optimization Models for Supply Chain, Planning and Scheduling)
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17 pages, 2181 KB  
Article
Sustainability Analysis of the Global Hydrogen Trade Network from a Resilience Perspective: A Risk Propagation Model Based on Complex Networks
by Sai Chen and Yuxi Tian
Energies 2025, 18(15), 3944; https://doi.org/10.3390/en18153944 - 24 Jul 2025
Viewed by 709
Abstract
Hydrogen is being increasingly integrated into the international trade system as a clean and flexible energy carrier, motivated by the global energy transition and carbon neutrality objectives. The rapid expansion of the global hydrogen trade network has simultaneously exposed several sustainability challenges, including [...] Read more.
Hydrogen is being increasingly integrated into the international trade system as a clean and flexible energy carrier, motivated by the global energy transition and carbon neutrality objectives. The rapid expansion of the global hydrogen trade network has simultaneously exposed several sustainability challenges, including a centralized structure, overdependence on key countries, and limited resilience to external disruptions. Based on this, we develop a risk propagation model that incorporates the absorption capacity of nodes to simulate the propagation of supply shortage risks within the global hydrogen trade network. Furthermore, we propose a composite sustainability index constructed from structural, economic, and environmental resilience indicators, enabling a systematic assessment of the network’s sustainable development capacity under external shock scenarios. Findings indicate the following: (1) The global hydrogen trade network is undergoing a structural shift from a Western Europe-dominated unipolar configuration to a more polycentric pattern. Countries such as China and Singapore are emerging as key hubs linking Eurasian regions, with trade relationships among nations becoming increasingly dense and diversified. (2) Although supply shortage shocks trigger structural disturbances, economic losses, and risks of carbon rebound, their impacts are largely concentrated in a limited number of hub countries, with relatively limited disruption to the overall sustainability of the system. (3) Countries exhibit significant heterogeneity in structural, economic, and environmental resilience. Risk propagation demonstrates an uneven pattern characterized by hub-induced disruptions, chain-like transmission, and localized clustering. Accordingly, policy recommendations are proposed, including the establishment of a polycentric coordination mechanism, the enhancement of regional emergency coordination mechanisms, and the advancement of differentiated capacity-building efforts. Full article
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44 pages, 1067 KB  
Review
Toward Adaptive and Immune-Inspired Viable Supply Chains: A PRISMA Systematic Review of Mathematical Modeling Trends
by Andrés Polo, Daniel Morillo-Torres and John Willmer Escobar
Mathematics 2025, 13(14), 2225; https://doi.org/10.3390/math13142225 - 8 Jul 2025
Cited by 5 | Viewed by 3485
Abstract
This study presents a systematic literature review on the mathematical modeling of resilient and viable supply chains, grounded in the PRISMA methodology and applied to a curated corpus of 235 peer-reviewed scientific articles published between 2011 and 2025. The search strategy was implemented [...] Read more.
This study presents a systematic literature review on the mathematical modeling of resilient and viable supply chains, grounded in the PRISMA methodology and applied to a curated corpus of 235 peer-reviewed scientific articles published between 2011 and 2025. The search strategy was implemented across four major academic databases (Scopus and Web of Science) using Boolean operators to capture intersections among the core concepts of supply chains, resilience, viability, and advanced optimization techniques. The screening process involved a double manual assessment of titles, abstracts, and full texts, based on inclusion criteria centered on the presence of formal mathematical models, computational approaches, and thematic relevance. As a result of the selection process, six thematic categories were identified, clustering the literature according to their analytical objectives and methodological approaches: viability-oriented modeling, resilient supply chain optimization, agile and digitally enabled supply chains, logistics optimization and network configuration, uncertainty modeling, and immune system-inspired approaches. These categories were validated through a bibliometric analysis and a thematic map that visually represents the density and centrality of core research topics. Descriptive analysis revealed a significant increase in scientific output starting in 2020, driven by post-pandemic concerns and the accelerated digitalization of logistics operations. At the methodological level, a high degree of diversity in modeling techniques was observed, with an emphasis on mixed-integer linear programming (MILP), robust optimization, multi-objective modeling, and the increasing use of bio-inspired algorithms, artificial intelligence, and simulation frameworks. The results confirm a paradigm shift toward integrative frameworks that combine robustness, adaptability, and Industry 4.0 technologies, as well as a growing interest in biological metaphors applied to resilient system design. Finally, the review identifies research gaps related to the formal integration of viability under disruptive scenarios, the operationalization of immune-inspired models in logistics environments, and the need for hybrid approaches that jointly address resilience, agility, and sustainability. Full article
(This article belongs to the Section D2: Operations Research and Fuzzy Decision Making)
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41 pages, 883 KB  
Article
Dependent-Chance Goal Programming for Sustainable Supply Chain Design: A Reinforcement Learning-Enhanced Salp Swarm Approach
by Yassine Boutmir, Rachid Bannari, Achraf Touil, Mouhsene Fri and Othmane Benmoussa
Sustainability 2025, 17(13), 6079; https://doi.org/10.3390/su17136079 - 2 Jul 2025
Viewed by 762
Abstract
The Sustainable Supply Chain Network Design Problem (SSCNDP) is to determine the optimal network configuration and resource allocation that achieve the trade-off among economic, environmental, social, and resilience objectives. The Sustainable Supply Chain Network Design Problem (SSCNDP) involves determining the optimal network configuration [...] Read more.
The Sustainable Supply Chain Network Design Problem (SSCNDP) is to determine the optimal network configuration and resource allocation that achieve the trade-off among economic, environmental, social, and resilience objectives. The Sustainable Supply Chain Network Design Problem (SSCNDP) involves determining the optimal network configuration and resource allocation that allows trade-off among economic, environmental, social, and resilience objectives. This paper addresses the SSCNDP under hybrid uncertainty, which combines objective randomness got from historical data, and subjective beliefs induced by expert judgment. Building on chance theory, we formulate a dependent-chance goal programming model that specifies target probability levels for achieving sustainability objectives and minimizes deviations from these targets using a lexicographic approach. To solve this complex optimization problem, we develop a hybrid intelligent algorithm that combines uncertain random simulation with Reinforcement Learning-enhanced Salp Swarm Optimization (RL-SSO). The proposed RL-SSO algorithm is benchmarked against standard metaheuristics—Genetic Algorithm (GA), Particle Swarm Optimization (PSO), Differential Evolution (DE), and standard SSO, across diverse problem instances. Results show that our method consistently outperforms these techniques in both solution quality and computational efficiency. The paper concludes with managerial insights and discusses limitations and future research directions. Full article
(This article belongs to the Special Issue Sustainable Operations and Green Supply Chain)
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30 pages, 2543 KB  
Article
Sustainable Supply Chain Strategies for Modular-Integrated Construction Using a Hybrid Multi-Agent–Deep Learning Approach
by Ali Attajer, Boubakeur Mecheri, Imane Hadbi, Solomon N. Amoo and Anass Bouchnita
Sustainability 2025, 17(12), 5434; https://doi.org/10.3390/su17125434 - 12 Jun 2025
Cited by 3 | Viewed by 2020
Abstract
Modular integrated construction (MiC) is a cutting-edge approach to construction that significantly improves efficiency and reduces project timelines by prefabricating entire building modules off-site. Despite the operational benefits of MiC, the carbon footprint of its extensive supply chain remains understudied. This study develops [...] Read more.
Modular integrated construction (MiC) is a cutting-edge approach to construction that significantly improves efficiency and reduces project timelines by prefabricating entire building modules off-site. Despite the operational benefits of MiC, the carbon footprint of its extensive supply chain remains understudied. This study develops a hybrid approach that combines multi-agent simulation (MAS) with deep learning to provide scenario-based estimations of CO2 emissions, costs, and schedule performance for MiC supply chain. First, we build an MAS model of the MiC supply chain in AnyLogic, representing suppliers, the prefabrication plant, road transport fleets, and the destination site as autonomous agents. Each agent incorporates activity data and emission factors specific to the process. This enables us to translate each movement, including prefabricated components of construction deliveries, module transfers, and module assembly, into kilograms of CO2 equivalent. We generate 23,000 scenarios for vehicle allocations using the multi-agent model and estimate three key performance indicators (KPIs): cumulative carbon footprint, logistics cost, and project completion time. Then, we train artificial neural network and statistical regression machine learning algorithms to captures the non-linear interactions between fleet allocation decisions and project outcomes. Once trained, the models are used to determine optimal fleet allocation strategies that minimize the carbon footprint, the completion time, and the total cost. The approach can be readily adapted to different MiC configurations and can be extended to include supply chain, production, and assembly disruptions. Full article
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32 pages, 6909 KB  
Article
Sustainable Governance of the Global Rare Earth Industry Chains: Perspectives of Geopolitical Cooperation and Conflict
by Chunxi Liu, Fengxiu Zhou, Jiayi Jiang and Huwei Wen
Sustainability 2025, 17(11), 4881; https://doi.org/10.3390/su17114881 - 26 May 2025
Cited by 2 | Viewed by 2234
Abstract
As critical strategic mineral resources underpinning high-tech industries and national defense security, rare earth elements have become a central focus of international competition, with their global industrial chain configuration deeply intertwined with geopolitical dynamics. Leveraging a novel multilateral database encompassing 140 countries’ geopolitical [...] Read more.
As critical strategic mineral resources underpinning high-tech industries and national defense security, rare earth elements have become a central focus of international competition, with their global industrial chain configuration deeply intertwined with geopolitical dynamics. Leveraging a novel multilateral database encompassing 140 countries’ geopolitical relationships and rare earth trade flows (2001–2023), this study employs social network analysis and temporal exponential random graph models (TERGMs) to decode structural interdependencies across upstream mineral concentrates, midstream smelting, and downstream permanent magnet sectors. Empirical results show that topological density trajectories reveal intensified network coupling, with upstream/downstream sectors demonstrating strong clustering. Geopolitical cooperation and conflict exert differential impacts along the value chain: downstream trade exhibits heightened sensitivity to cooperative effects, whereas midstream trade suffers the most pronounced obstruction from conflicts. Cooperation fosters long-term trade relationships, whereas conflicts primarily impose short-term suppression. In addition, centrality metrics reveal asymmetric mechanisms. Each unit increase in cooperation degree centrality amplifies the mid/downstream trade by 3.29 times, whereas conflict centrality depresses the midstream trade by 4.76%. The eigenvector centrality of cooperation hub nations enhances the midstream trade probability by 5.37-fold per unit gain, in contrast with the 25.09% midstream trade erosion from conflict-prone nations’ centrality increments. These insights provide implications for mitigating geopolitical risks and achieving sustainable governance in key mineral resource supply chains. Full article
(This article belongs to the Section Economic and Business Aspects of Sustainability)
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28 pages, 4657 KB  
Article
AI-Enabled Supply Chain Management: A Bibliometric Analysis Using VOSviewer and RStudio Bibliometrix Software Tools
by Mihaela Gabriela Belu and Ana Maria Marinoiu
Sustainability 2025, 17(5), 2092; https://doi.org/10.3390/su17052092 - 28 Feb 2025
Cited by 5 | Viewed by 4773
Abstract
Artificial intelligence (AI) is fundamentally transforming the management of supply chain activities, offering companies the opportunity to configure resilient, transparent, and sustainable supply chains. Given its importance, this paper presents aspects of the implementation of artificial intelligence in supply chain management by performing [...] Read more.
Artificial intelligence (AI) is fundamentally transforming the management of supply chain activities, offering companies the opportunity to configure resilient, transparent, and sustainable supply chains. Given its importance, this paper presents aspects of the implementation of artificial intelligence in supply chain management by performing a bibliometric analysis of 400 scientific papers published between 2010 and 2024 and indexed in the Scopus database. The analysis was based on the Bibliometrix 4.4.2 and VOSviewer 1.6.19 software to identify the most important authors and journals of interest for the researched topic. Keyword co-occurrence and co-citation analyses were used to map intellectual networks and highlight themes of interest. The research results confirm the increase in scientific interest in the field of applying AI in supply chain management, highlighting the advantages of implementing this technology in supply chain management. At the same time, the recommendations and conclusions of this paper will be useful to both academic researchers and business professionals to identify potential areas of collaboration with the aim of developing supply chain strategies that contribute to the competitiveness of companies that are part of the network. Full article
(This article belongs to the Special Issue Digital Transformation of Supply Chain Innovation)
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18 pages, 1780 KB  
Article
Enhancing Efficiency in the Healthcare Sector Through Multi-Objective Optimization of Freight Cost and Delivery Time in the HIV Drug Supply Chain Using Machine Learning
by Amirkeyvan Ghazvinian, Bo Feng and Junwen Feng
Systems 2025, 13(2), 91; https://doi.org/10.3390/systems13020091 - 31 Jan 2025
Cited by 2 | Viewed by 2710
Abstract
The purpose of this paper is to examine the optimization of the HIV drug supply chain, with a dual focus on minimizing freight costs and delivery times. With the help of a dataset containing 10,325 instances of supply chain transactions, key variables, including [...] Read more.
The purpose of this paper is to examine the optimization of the HIV drug supply chain, with a dual focus on minimizing freight costs and delivery times. With the help of a dataset containing 10,325 instances of supply chain transactions, key variables, including “Country”, “Vendor INCO Term”, and “Shipment Mode”, were examined in order to develop a predictive model using Artificial Neural Networks (ANN) employing a Multi-Layer Perceptron (MLP) architecture. A set of ANN models were trained to forecast “freight cost” and “delivery time” based on four principal design variables: “Line Item Quantity”, “Pack Price”, “Unit of Measure (Per Pack)”, and “Weight (Kilograms)”. According to performance metrics analysis, these models demonstrated predictive accuracy following training. An optimization algorithm, configured with an “active-set” algorithm, was then used to minimize the combined objective function of freight cost and delivery time. Both freight costs and delivery times were significantly reduced as a result of the optimization. This study illustrates the potent application of machine learning and optimization algorithms to the enhancement of supply chain efficiency. This study provides a blueprint for cost reduction and improved service delivery in critical medication supply chains based on the methodology and outcomes. Full article
(This article belongs to the Special Issue Systems Methodology in Sustainable Supply Chain Resilience)
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24 pages, 2765 KB  
Article
Valorization of Biomass Through Anaerobic Digestion and Hydrothermal Carbonization: Integrated Process Flowsheet and Supply Chain Network Optimization
by Sanja Potrč, Aleksandra Petrovič, Jafaru M. Egieya and Lidija Čuček
Energies 2025, 18(2), 334; https://doi.org/10.3390/en18020334 - 14 Jan 2025
Cited by 3 | Viewed by 1452
Abstract
Utilization of biomass through anaerobic digestion and hydrothermal carbonization is crucial to maximize resource efficiency. At the same time, supply chain integration ensures sustainable feedstock management and minimizes environmental and logistical impacts, enabling a holistic approach to a circular bioeconomy. This study presents [...] Read more.
Utilization of biomass through anaerobic digestion and hydrothermal carbonization is crucial to maximize resource efficiency. At the same time, supply chain integration ensures sustainable feedstock management and minimizes environmental and logistical impacts, enabling a holistic approach to a circular bioeconomy. This study presents an integrated approach to simultaneously optimize the biomass supply chain network and process flowsheet, which includes anaerobic digestion, cogeneration, and hydrothermal carbonization. A three-layer supply chain network superstructure was hence developed to integrate the optimization of process variables with supply chain features such as transportation modes, feedstock supply, plant location, and demand location. A mixed-integer nonlinear programming model aimed at maximizing the economic performance of the system was formulated and applied to a case study of selected regions in Slovenia. The results show a great potential for the utilization of organic biomass with an annual after tax profit of 23.13 million USD per year, with the production of 245.70 GWh/yr of electricity, 298.83 GWh/yr of heat, and 185.08 kt/yr of hydrochar. The optimal configuration of the supply chain network, including the selection of supply zones, plant locations and demand locations, transportation links, and mode of transportation is presented, along with the optimal process variables within the plant. Full article
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