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Review

12 Citations

3,110 Views

26 Pages

Unravelling the Acute, Chronic and Steroid-Refractory Management of High-Grade Neurological Immune-Related Adverse Events: A Call to Action

Antonio Malvaso,
Pierpaolo Giglio,
Luca Diamanti,
Matteo Gastaldi,
Elisa Vegezzi,
Andrea Pace,
Paola Bini and
Enrico Marchioni

Brain Sci.2024, 14(8), 764;https://doi.org/10.3390/brainsci14080764

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29 July 2024

Rare side effects of immune-checkpoint inhibitors (ICIs) are known as neurological immune-related adverse events (n-irAEs). Typically, n-irAEs affect the peripheral nervous system, primarily presenting as myositis, polyradiculoneuropathy, or cranial...

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Article

3 Citations

2,391 Views

17 Pages

Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors

Lisa Arnold,
Monika Morak,
Nora Kramer,
Carola Berking,
Matthias Schefzyk,
Jessica C. Hassel,
Mirjana Ziemer,
Lars E. French,
Ralf Gutzmer and
Lucie Heinzerling
+ 1 author

Cancers2025, 17(11), 1845;https://doi.org/10.3390/cancers17111845

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31 May 2025

Background/Objectives: Cutaneous side effects are the most common immune-related adverse events (irAEs) caused by immune checkpoint inhibitors (ICIs) and affect 70–90% of patients. Besides diverse types of exanthema, rare skin toxicity includes...

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