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18 pages, 2666 KiB  
Article
Allometric Equations for Aboveground Biomass Estimation in Natural Forest Trees: Generalized or Species-Specific?
by Yuxin Shang, Yutong Xia, Xiaodie Ran, Xiao Zheng, Hui Ding and Yanming Fang
Diversity 2025, 17(7), 493; https://doi.org/10.3390/d17070493 - 18 Jul 2025
Abstract
Accurate estimation of aboveground biomass (AGB) in tree–shrub communities is critical for quantifying forest ecosystem productivity and carbon sequestration potential. Although generalized allometric equations offer expediency in natural forest AGB estimation, their neglect of interspecific variability introduces methodological pitfalls. Precise AGB prediction necessitates [...] Read more.
Accurate estimation of aboveground biomass (AGB) in tree–shrub communities is critical for quantifying forest ecosystem productivity and carbon sequestration potential. Although generalized allometric equations offer expediency in natural forest AGB estimation, their neglect of interspecific variability introduces methodological pitfalls. Precise AGB prediction necessitates resolving two biological constraints: phylogenetic conservation of allometric coefficients and ontogenetic regulation of scaling relationships. This study establishes an integrated framework combining the following: (1) phylogenetic signal detection (Blomberg’s K/Pagel’s λ) across 157 species’ allometric equations, revealing weak but significant evolutionary constraints (λ = 0.1249, p = 0.0027; K ≈ 0, p = 0.621); (2) hierarchical error decomposition of 9105 stems in a Mt. Wuyishan forest dynamics plot (15 species), identifying family-level error stratification (e.g., Theaceae vs. Myrtaceae, Δerror > 25%); (3) ontogenetic trajectory analysis of Castanopsis eyrei between Mt. Wuyishan and Mt. Huangshan, demonstrating significant biomass deviations in small trees (5–15 cm DBH, p < 0.05). Key findings resolve the following hypotheses: (1) absence of strong phylogenetic signals validates generalized models for phylogenetically diverse communities; (2) ontogenetic regulation dominates error magnitude, particularly in early developmental stages; (3) differential modeling is recommended: species-specific equations for pure forests/seedlings vs. generalized equations for mixed mature forests. This work establishes an error hierarchy: ontogeny > taxonomy > phylogeny, providing a mechanistic basis for optimizing forest carbon stock assessments. Full article
(This article belongs to the Section Plant Diversity)
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15 pages, 5226 KiB  
Article
Enhancing Conservation Efforts of Stephanopodium engleri Through Vegetative Propagation: Effects of IBA and Cutting Types
by Giselly Mota da Silva, Evandro Alves Vieira, Luiz Palhares Neto, Silvio Ramos, Markus Gastauer and Cecílio Frois Caldeira
Plants 2025, 14(14), 2116; https://doi.org/10.3390/plants14142116 - 9 Jul 2025
Viewed by 252
Abstract
Stephanopodium engleri Baill. is an endangered tree species from the Dichapetalaceae family and endemic to the Iron Quadrangle region of Brazil. Recalcitrance and low seed viability limit conventional seedling production, making vegetative propagation a crucial alternative for conservation efforts. This study evaluated the [...] Read more.
Stephanopodium engleri Baill. is an endangered tree species from the Dichapetalaceae family and endemic to the Iron Quadrangle region of Brazil. Recalcitrance and low seed viability limit conventional seedling production, making vegetative propagation a crucial alternative for conservation efforts. This study evaluated the rooting and sprouting potential of different cutting types (apical, middle, and basal segments from the main stem, as well as the tip and the herbaceous and woody segments from the lateral branches) treated with Indole-3-Butyric Acid (IBA) at varying concentrations (0, 1, 2, 3, and 4 g L−1) and immersion durations (5 s to 10 min). Cuttings were collected from 12-month-old plants grown under controlled conditions and planted in Carolina Soil® substrate after treatment. Sprouting and rooting rates varied significantly between cutting types, with basal main stem cuttings showing the highest rooting success, particularly at 3 g L−1 of IBA. These cuttings also exhibited more and longer roots and enhanced sprouting-related biometric traits. Shorter immersion times (15 s and 1 min) were the most effective, promoting root formation while avoiding the potential inhibitory effects of prolonged exposure. Our findings provide a practical protocol for large-scale seedling production of S. engleri while minimizing impacts on wild populations. The effective use of vegetative propagation could facilitate the expansion of S. engleri populations in their natural habitats, enhancing conservation efforts and ensuring sustainable species management. Full article
(This article belongs to the Special Issue Physiology and Seedling Production of Plants)
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26 pages, 997 KiB  
Article
The Effects of Land Use Mix on Urban Vitality: A Systemic Conceptualization and Mechanistic Exploration
by Yuefei Zhuo, Hangang Hu and Guan Li
Systems 2025, 13(7), 542; https://doi.org/10.3390/systems13070542 - 2 Jul 2025
Viewed by 233
Abstract
Urban vitality, a critical emergent property of complex urban systems, is pivotal for sustainable, human-oriented urbanization. While land use mix (LUM) is recognized as a key strategy for shaping these systems, the systemic mechanisms through which its multifaceted dimensions influence urban vitality across [...] Read more.
Urban vitality, a critical emergent property of complex urban systems, is pivotal for sustainable, human-oriented urbanization. While land use mix (LUM) is recognized as a key strategy for shaping these systems, the systemic mechanisms through which its multifaceted dimensions influence urban vitality across spatio-temporal scales remain underexplored. This study examines the complex and spatially heterogeneous impacts of land use mix on 24 h urban vitality in Ningbo, China, conceptualizing the city as a dynamic socio-spatial system. By integrating multi-source data (Baidu Maps, POI, and OSM) and employing OLS and geographically weighted regression (GWR) models, we unravel these systemic relationships. Key findings include the following: (1) LUM significantly enhances urban vitality, acting as a crucial urban system configuration for both daytime and nighttime activity. (2) The efficacy of LUM stems more from systemic interconnections—convenient access to adjacent spaces (proximity) and functional coordination among diverse land uses—than mere compositional diversity, emphasizing the importance of interrelated elements within the urban fabric. (3) The system’s response to LUM exhibits significant spatial and temporal heterogeneity; proximity’s impact is most variable, while diversity and coordination effects are more stable, underscoring the dynamic and context-dependent nature of these interactions. (4) System-adaptive strategies are crucial: newly developed urban areas benefit from foundational infrastructure and land use diversity (system inputs), while revitalizing older towns requires optimizing spatial accessibility and functional coordination (enhancing existing system linkages). These findings advance the theoretical systems-based theoretical understanding of the LUM–vitality nexus while offering practical insights for urban planners and policymakers. Full article
22 pages, 2784 KiB  
Article
Phytoremediation of Soils Contaminated with Mercury Using Piper marginatum in Ayapel, Colombia
by Mayra De la Rosa-Mendoza, Mario Viña-Pico and José Marrugo-Negrete
Soil Syst. 2025, 9(3), 68; https://doi.org/10.3390/soilsystems9030068 - 1 Jul 2025
Viewed by 367
Abstract
The main problem associated with mining is the release of heavy metals into the environment, impacting the soil and overall environment. Mercury is one of the most contaminating heavy metals. It is present in soils, sediments, surface water, and groundwater. The objective of [...] Read more.
The main problem associated with mining is the release of heavy metals into the environment, impacting the soil and overall environment. Mercury is one of the most contaminating heavy metals. It is present in soils, sediments, surface water, and groundwater. The objective of this research was to evaluate the phytoremediation carried out by the native plant Piper marginatum, in soils contaminated by mercury in an experimental lot in the municipality of Ayapel, where artisanal and small-scale gold mining is carried out. A soil phytoremediation process was carried out at a field scale using the plant species Piper marginatum in a 2.4 ha plot historically contaminated by gold mining, located in Ayapel, Colombia. A completely randomized experimental design was used with nine experimental plots, which were planted with Piper marginatum, and three controls, without planting. Through an initial soil sampling, the physicochemical characteristics and total mercury content in this matrix were determined. Piper marginatum seedlings were planted in the experimental plots and remained in the field for a period of six months. The plant biomass was collected and a final soil sampling was performed for total mercury analysis to determine the total percentage of mercury removal. The results obtained indicated mercury concentrations in soils ranging from 40.80 to 52,044.4 µg kg−1 in the experimental plots and ranged from 55.9 to 2587.4 µg kg−1 in the controls. In the plots planted with Piper marginatum, a 37.3% decrease in total mercury was achieved, while in the plots without planting there was a 23.5% increase. In plants, the average T Hg concentrations in the roots, stems, and leaves were 109.2 µg kg−1, 80.6 µg kg−1, and 122.6 µg kg−1, respectively. An average BCF < 1 and an average TF > 1 were obtained. Full article
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14 pages, 236 KiB  
Article
Influence of Field Trips on Adolescent Environmental Stewardship: Examining the Role of the Dominant Social Paradigm
by Gita Bhushal, Meghann Smith, Pankaj Lal and Neeraj Vedwan
World 2025, 6(3), 88; https://doi.org/10.3390/world6030088 - 1 Jul 2025
Viewed by 301
Abstract
Promoting environmental stewardship among youths is crucial for inspiring collaborative, multi-generational actions to tackle long-term environmental challenges. This research study explores the impact of an environmental education (EE) field trip, which highlighted wastewater management and renewable energy technology, on high school students using [...] Read more.
Promoting environmental stewardship among youths is crucial for inspiring collaborative, multi-generational actions to tackle long-term environmental challenges. This research study explores the impact of an environmental education (EE) field trip, which highlighted wastewater management and renewable energy technology, on high school students using the revised new ecological paradigm (NEP) scale as a key metric in a pre-post survey, which uses traditionally pro (NEP) and anti (dominant social paradigm, DSP) conservationist statements to measure beliefs towards the environment. When applying the Wilcoxon signed-rank test (null hypothesis t = 0, no change) to the series of environmental stewardship action questions “___ is an extremely important part of protecting the environment”, we identified ten out of the thirteen scale questions to show significant change, all of which were positive. Additionally, the overall impact score was positive and significant (p ≤ 0.05). This finding demonstrates that respondents felt more strongly that these variables played a role in protecting the environment after experiencing the field trip. This suggests that exposure to environmental management intervention strategies utilizing man-made infrastructure and technology may enhance human capability to positively influence the environment and mitigate environmental threats, potentially alleviating concerns about environmental issues. These results suggest that environmental stewardship in youth needs to be reconceptualized in an increasingly STEM-focused world, and a new metric should be developed to assess environmental beliefs. Full article
25 pages, 3376 KiB  
Article
A Multi-Level Knowledge Distillation for Enhanced Crop Segmentation in Precision Agriculture
by Zhiyong Li, Lan Xiang, Jun Sun, Dingyi Liao, Lijia Xu and Mantao Wang
Agriculture 2025, 15(13), 1418; https://doi.org/10.3390/agriculture15131418 - 30 Jun 2025
Viewed by 399
Abstract
In this paper, we propose a knowledge distillation framework specifically designed for semantic segmentation tasks in agricultural scenarios. This framework aims to address several prevalent challenges in smart agriculture, including limited computational resources, strict real-time constraints, and suboptimal segmentation accuracy on cropped images. [...] Read more.
In this paper, we propose a knowledge distillation framework specifically designed for semantic segmentation tasks in agricultural scenarios. This framework aims to address several prevalent challenges in smart agriculture, including limited computational resources, strict real-time constraints, and suboptimal segmentation accuracy on cropped images. Traditional single-level feature distillation methods often suffer from insufficient knowledge transfer and inefficient utilization of multi-scale features, which significantly limits their ability to accurately segment complex crop structures in dynamic field environments. To overcome these issues, we propose a multi-level distillation strategy that leverages feature and embedding patch distillation, combining high-level semantic features with low-level texture details for joint distillation. This approach enables the precise capture of fine-grained agricultural elements, such as crop boundaries, stems, petioles, and weed clusters, which are critical for achieving robust segmentation. Additionally, we integrated an enhanced attention mechanism into the framework, which effectively strengthens and fuses key crop-related features during the distillation process, thereby further improving the model’s performance and image understanding capabilities. Extensive experiments on two agricultural datasets (sweet pepper and sugar) demonstrate that our method improves segmentation accuracy by 7.59% and 6.79%, without significantly increasing model complexity. Further validation shows that our approach exhibits strong generalization capabilities on two widely used public datasets, proving its applicability beyond agricultural domains. Full article
(This article belongs to the Section Digital Agriculture)
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26 pages, 7559 KiB  
Article
A Meta-Frontier Approach to Evaluating the Environmental Efficiency of Coastal Ports: Implications for Port Sustainability
by Gaofeng Gu, Jiewei Zhang and Xiaofeng Pan
J. Mar. Sci. Eng. 2025, 13(7), 1272; https://doi.org/10.3390/jmse13071272 - 30 Jun 2025
Viewed by 313
Abstract
As pivotal nodes in maritime logistics networks, ports face mounting pressure to reconcile economic growth with environmental sustainability. Although the SBM-Undesirable model has been extensively applied to assess port environmental efficiency (PEE), most applications assume strong disposability and disregard heterogeneity in technological capacities [...] Read more.
As pivotal nodes in maritime logistics networks, ports face mounting pressure to reconcile economic growth with environmental sustainability. Although the SBM-Undesirable model has been extensively applied to assess port environmental efficiency (PEE), most applications assume strong disposability and disregard heterogeneity in technological capacities across different port scales, potentially biasing the assessments. To overcome these limitations, coastal ports are initially categorized into three subgroups based on operational scale criteria. A meta-frontier SBM-Undesirable model incorporating weak disposability is then developed to evaluate PEE. Dynamic characteristics are further explored via the Global Malmquist Index. Results indicate substantial disparities between subgroup frontiers and the meta-frontier. The average group PEE (0.732) exceeded the meta PEE (0.570), implying potential overestimation under homogeneity assumptions. Large-sized ports, with a mean technology gap ratio (TGR) of 0.956, operated near the meta-frontier, whereas medium-sized and small-sized ports, with TGRs of 0.770 and 0.600 respectively, exhibited substantial technological gaps. Total factor productivity (TFP) demonstrated a volatile upward trend, averaging 6.8% annual growth. In large-sized and medium-sized ports, TFP growth was primarily driven by technological innovation, whereas in small-sized ports, it stemmed from combined improvements in technical efficiency and technological level. These insights underscore the necessity of differentiated decarbonization strategies for port management. Full article
(This article belongs to the Special Issue Maritime Transport and Port Management)
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21 pages, 2985 KiB  
Article
Characterization of Biochar from Hovenia dulcis Thunb. and Mimosa scabrella Benth. Species from the Mixed Ombrophyllous Forest
by Florian Empl, Miriam Schatzl, Sonja Kleucker, Alexandre Techy de Almeida Garrett, Fernando Augusto Ferraz, Luiz Henrique Natalli, Dimas Agostinho da Silva, Eduardo da Silva Lopes, Afonso Figueiredo Filho and Stefan Pelz
Forests 2025, 16(7), 1077; https://doi.org/10.3390/f16071077 - 27 Jun 2025
Viewed by 328
Abstract
The Mixed Ombrophyllous Forest (MOF), inserted in the Atlantic Forest biome, is of great ecological value, with deficient management strategies. In this context, sustainable management helps to promote the regeneration and growth of individual trees and control others, while maintaining the natural forest [...] Read more.
The Mixed Ombrophyllous Forest (MOF), inserted in the Atlantic Forest biome, is of great ecological value, with deficient management strategies. In this context, sustainable management helps to promote the regeneration and growth of individual trees and control others, while maintaining the natural forest structure. This study therefore aimed to discuss opportunities and limitations of biochar, produced from two species from the MOF, which are currently only utilized to a limited extent in the study area in southern Brazil. A slow pyrolysis process at a lab scale was designed, biochar was produced, and key properties were analyzed from Hovenia dulcis Thunb. (chosen as an invasive species) and Mimosa scabrella Benth. (chosen as a native, fast-growing species), including branches and stems. The results showed that branches of Mimosa scabrella (BMS) had the highest biochar yield (30.32 ± 0.3%) and the highest electrical conductivity (415.08 ± 24.75 mS cm−1). Stems of Mimosa scabrella (SMS) showed the highest higher heating value (HHV—31.76 ± 0.01 MJ kg−1), lower heating value (LHV—31.03 ± 0.01 MJ kg−1), and energy yield (49.1%), while the branches of Hovenia dulcis (BHD) showed the lowest values. For the elemental analysis, SMS showed the best results, with the highest amount of fixed carbon (78.62 ± 0.22%) and carbon content (85.87 ± 0.083%), and consequently the lowest amount of ash (3.52 ± 0.08%). BHD showed a better water-holding capacity (303.26 ± 15.21%) and higher pH value (7.65 ± 0.14). The investigations conducted on the biochar from both species indicate a strong suitability of these woods for producing high-quality biochar. Full article
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18 pages, 3351 KiB  
Article
Biosynthesis of Bioactive Human Neurotrophic Factor 3 in Silkworms and Its Biomedical Applications
by Wenjing Geng, Liang Lu, Tangmin Li, Mingyi Zhou, Wei Chen, Hao Tan, Debin Zhong, Guanwang Shen, Ping Lin, Qingyou Xia, Ping Zhao and Zhiqing Li
Insects 2025, 16(7), 676; https://doi.org/10.3390/insects16070676 - 27 Jun 2025
Viewed by 361
Abstract
Neurotrophic factor 3 (NT-3), a potent neurotrophin, promotes neuronal survival and axonal regeneration while demonstrating a unique capacity to induce lineage-specific differentiation of pluripotent stem cells into functional neurons, underscoring its therapeutic potential in neural repair. Despite these advantages, the large-scale production of [...] Read more.
Neurotrophic factor 3 (NT-3), a potent neurotrophin, promotes neuronal survival and axonal regeneration while demonstrating a unique capacity to induce lineage-specific differentiation of pluripotent stem cells into functional neurons, underscoring its therapeutic potential in neural repair. Despite these advantages, the large-scale production of recombinant human NT-3 with preserved structure integrity and functional bioactivity remains a critical challenge. This study takes advantage of the silk gland bioreactor of silkworms for the recombinant expression of human NT-3 protein on a large scale. Our findings reveal that NT-3 was successfully expressed in the middle silk gland of silkworms and secreted into the silk fibers, achieving a yield of up to 0.5 mg of bioactive NT-3 per gram of cocoon weight. The engineered NT-3-functionalized silk material demonstrates no cytotoxicity and significantly enhanced the proliferation, migration, and differentiation of neural cells compared to natural silk protein. Importantly, this functionalized material also promotes neurite outgrowth in HT-22 cells. These results collectively underscore the high bioactivity of the recombinant human NT-3 protein produced in the silkworm silk gland. The ongoing fabrication of NT-3-incorporated silk-based materials holds considerable promise for advancing tissue engineering and nerve regeneration applications. Full article
(This article belongs to the Special Issue Recent Studies on Resource Insects)
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35 pages, 2556 KiB  
Article
Technical Trends, Radical Innovation, and the Economics of Sustainable, Industrial-Scale Electric Heating for Energy Efficiency and Water Savings
by A. A. Vissa and J. A. Sekhar
Sustainability 2025, 17(13), 5916; https://doi.org/10.3390/su17135916 - 27 Jun 2025
Viewed by 654
Abstract
This article examines the energy efficiency and climate impact of various heating methods commonly employed across industrial sectors. Fossil fuel combustion heat sources, which are predominantly employed for industrial heating, contribute significantly to atmospheric pollution and associated asset losses. The electrification of industrial [...] Read more.
This article examines the energy efficiency and climate impact of various heating methods commonly employed across industrial sectors. Fossil fuel combustion heat sources, which are predominantly employed for industrial heating, contribute significantly to atmospheric pollution and associated asset losses. The electrification of industrial heating has the potential to substantially reduce the total energy consumed in industrial heating processes and significantly mitigate the rate of global warming. Advances in electrical heating technologies are driven by enhanced energy conversion, compactness, and precision control capabilities, ensuring attractive financial payback periods for clean, energy-efficient equipment. These advancements stem from the use of improved performance materials, process optimization, and waste heat utilization practices, particularly at high temperatures. The technical challenges associated with large-scale, heavy-duty electric process heating are addressed through the novel innovations discussed in this article. Electrification and the corresponding energy efficiency improvements reduce the water consumed for industrial steam requirements. The article reviews new technologies that replace conventional process gas heaters and pressure boilers with efficient electric process gas heaters and instant steam generators, operating in the high kilowatt and megawatt power ranges with very high-temperature capabilities. Financial payback calculations for energy-optimized processes are illustrated with examples encompassing a range of comparative energy costs across various temperatures. The economics and implications of waste heat utilization are also examined in this article. Additionally, the role of futuristic, radical technical innovations is evaluated as a sustainable pathway that can significantly lower energy consumption without compromising performance objectives. The potential for a new paradigm of self-organization in processes and final usage objectives is briefly explored for sustainable innovations in thermal engineering and materials development. The policy implications and early adoption of large-scale, energy-efficient thermal electrification are discussed in the context of temperature segmentation for industrial-scale processes and climate-driven asset losses. Policy shifts towards incentivizing energy efficiency at the manufacturing level of heater use are recommended as a pathway for deep decarbonization. Full article
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14 pages, 1780 KiB  
Systematic Review
Effects of Prenatal Arsenic, Cadmium, and Manganese Exposure on Neurodevelopment in Children: A Systematic Review and Meta-Analysis
by Rui Su, Yi Jiang, Weikun Li, Wencheng Ding and Ling Feng
Medicina 2025, 61(7), 1143; https://doi.org/10.3390/medicina61071143 - 25 Jun 2025
Viewed by 253
Abstract
Objective: The aim of this study was to investigate the effects of prenatal heavy metal (arsenic, cadmium, manganese) exposure on infant neurodevelopment through a systematic review and meta-analysis, elucidating the toxicological mechanisms and dose–response relationships for consideration in environmental risk assessment. Methods [...] Read more.
Objective: The aim of this study was to investigate the effects of prenatal heavy metal (arsenic, cadmium, manganese) exposure on infant neurodevelopment through a systematic review and meta-analysis, elucidating the toxicological mechanisms and dose–response relationships for consideration in environmental risk assessment. Methods: Following the PRISMA guidelines, systematic searches were conducted in PubMed, Embase, and other databases, ultimately resulting in 17 observational studies involving 6907 participants. Results: Arsenic (As): A 50% increase in arsenic exposure was associated with a reduction of 0.51 points in the Mental Development Index (MDI; 95% CI: −1.43 to 0.4) and 0.15 points in the Psychomotor Development Index (PDI; 95% CI: −0.96 to 0.65). However, these results did not achieve statistical significance (p > 0.05). Cadmium (Cd): Prenatal cadmium exposure significantly decreased the Full-Scale Intelligence Quotient (FSIQ) in children aged 5–9 years. A 50% increase in cadmium exposure resulted in a 0.44-point drop in the FSIQ (95% CI: −0.67 to −0.21, p < 0.05), with stable effects (I2 = 0%). Manganese (Mn): Manganese exposure showed a negative association with the MDI (β = −0.11) and PDI (β = −0.18). However, a high degree of heterogeneity was observed (I2 = 20.89–73.35%), and some studies suggested potential risks even at low exposure levels. Sensitivity analyses indicated that the heterogeneity in the arsenic and manganese results mainly stemmed from individual study differences (e.g., sample characteristics), whereas the cadmium effects were consistent. Conclusions: Prenatal heavy metal exposure (notably cadmium) adversely impacts neurodevelopment, even at low doses. Future research should prioritize critical exposure windows, mixed effects, and sex-specific vulnerabilities. Strengthening environmental monitoring and prenatal guidelines is crucial to mitigate developmental risks. Full article
(This article belongs to the Section Obstetrics and Gynecology)
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19 pages, 3618 KiB  
Article
Comparison of Advanced Terrestrial and Aerial Remote Sensing Methods for Above-Ground Carbon Stock Estimation—A Comparative Case Study for a Hungarian Temperate Forest
by Botond Szász, Bálint Heil, Gábor Kovács, Diána Mészáros and Kornél Czimber
Remote Sens. 2025, 17(13), 2173; https://doi.org/10.3390/rs17132173 - 25 Jun 2025
Viewed by 346
Abstract
The increasing pace of climate-driven changes in forest ecosystems calls for reliable remote sensing techniques for quantifying above-ground carbon storage. In this article, we compare the methodology and results of traditional field surveys, mobile laser scanning, optical drone imaging and photogrammetry, and both [...] Read more.
The increasing pace of climate-driven changes in forest ecosystems calls for reliable remote sensing techniques for quantifying above-ground carbon storage. In this article, we compare the methodology and results of traditional field surveys, mobile laser scanning, optical drone imaging and photogrammetry, and both drone-based and light aircraft-based aerial laser scanning to determine forest stand parameters, which are suitable to estimate carbon stock. Measurements were conducted at four designated sampling points established during a large-scale project in deciduous and coniferous tree stands of the Dudles Forest, Hungary. The results of the surveys were first compared spatially and quantitatively, followed by a summary of the advantages and disadvantages of each method. The mobile laser scanner proved to be the most accurate, while optical surveying—enhanced with a new diameter measurement methodology based on detecting stem positions from the photogrammetric point cloud and measuring the diameter directly on the orthorectified images—also delivered promising results. Aerial laser scanning was the least accurate but provided coverage over large areas. Based on the results, we recommend adapting our carbon stock estimation methodology primarily to mobile laser scanning surveys combined with aerial laser scanned data. Full article
(This article belongs to the Collection Feature Paper Special Issue on Forest Remote Sensing)
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33 pages, 2002 KiB  
Review
Network Pharmacology Approaches to Myocardial Infarction Reperfusion Injury: Exploring Mechanisms, Pathophysiology, and Novel Therapies
by Joy Das, Ashok Kumar Sah, Ranjay Kumar Choudhary, Rabab H. Elshaikh, Utpal Bhui, Shreya Chowdhury, Anass M. Abbas, Manar G. Shalabi, Nadeem Ahmad Siddique, Raji Rubayyi Alshammari, Navjyot Trivedi, Khoula Salim Ali Buwaiqi, Said Al Ghenaimi and Pranav Kumar Prabhakar
Biomedicines 2025, 13(7), 1532; https://doi.org/10.3390/biomedicines13071532 - 23 Jun 2025
Viewed by 1208
Abstract
Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. While timely reperfusion therapies such as percutaneous coronary intervention (PCI) and thrombolysis are essential for salvaging ischemic myocardium, they can paradoxically exacerbate tissue injury through a process known as myocardial infarction [...] Read more.
Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide. While timely reperfusion therapies such as percutaneous coronary intervention (PCI) and thrombolysis are essential for salvaging ischemic myocardium, they can paradoxically exacerbate tissue injury through a process known as myocardial infarction reperfusion injury (MIRI). MIRI can contribute to up to 50% of the final infarct size, significantly diminishing the benefits of revascularization and leading to worsened cardiac outcomes. The pathophysiology of MIRI involves complex, interrelated mechanisms including oxidative stress, calcium overload, mitochondrial dysfunction, inflammatory responses, apoptosis, and dysregulated autophagy. Post-reperfusion recovery is further complicated by structural and functional abnormalities such as microvascular obstruction, endothelial dysfunction, and myocardial stunning. Clinically, distinguishing reperfusion injury from ischemic damage is challenging and often requires the use of sensitive biomarkers, such as cardiac troponins, alongside advanced imaging modalities. Although a range of pharmacological (e.g., antioxidants, calcium channel blockers, mitochondrial stabilizers, anti-inflammatory agents) and non-pharmacological (e.g., hypothermia, gene therapy, stem cell-based therapies) interventions have shown promise in preclinical studies, their clinical translation remains limited. This is largely due to the multifactorial and dynamic nature of MIRI. In this context, network pharmacology offers a systems-level approach to understanding the complex biological interactions involved in MIRI, facilitating the identification of multi-target therapeutic strategies. Integrating network pharmacology with omics technologies and precision medicine holds potential for advancing cardioprotective therapies. This review provides a comprehensive analysis of the molecular mechanisms underlying MIRI, examines the current clinical challenges, and explores emerging therapeutic strategies. Emphasis is placed on bridging the translational gap through validated, multi-target approaches and large-scale, multicenter clinical trials. Ultimately, this work aims to support the development of innovative and effective interventions for improving outcomes in patients with myocardial infarction. Full article
(This article belongs to the Section Molecular and Translational Medicine)
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16 pages, 2710 KiB  
Article
Selecting Optimal Hemp (Cannabis sativa L.) Varieties for Long Fibre Production in Western Europe
by Hanne Pappaert, Sophie Waegebaert, Katrien Vandepitte, Joos Latré, Svea Thienpondt, Sofie Vermeire, Alexandra De Raeve, Leen De Gelder and Veronique Troch
Agronomy 2025, 15(7), 1521; https://doi.org/10.3390/agronomy15071521 - 23 Jun 2025
Viewed by 319
Abstract
Industrial hemp (Cannabis sativa L.) is gaining renewed interest as a sustainable source of natural fibres, particularly in regions like Belgium, where well-established flax processing infrastructure exists. However, region-specific data on varietal performance for long fibre production remain limited, hindering large scale [...] Read more.
Industrial hemp (Cannabis sativa L.) is gaining renewed interest as a sustainable source of natural fibres, particularly in regions like Belgium, where well-established flax processing infrastructure exists. However, region-specific data on varietal performance for long fibre production remain limited, hindering large scale adoption by both farmers and processors. This study aimed to assess the agronomic performance of early- and late-flowering hemp varieties under temperate maritime conditions through a three-year field trial at two sites in Flanders (Belgium). The evaluation focused on key parameters including emergence rate, plant morphology, long fibre yield and quality. Results showed that successful crop establishment is critical, as poor emergence influenced stem diameter (increasing with decreasing emergence) and leads to reduced long fibre yields by up to 50% between tested sites. Significant yield differences between trial years were present at both sites, with the biomass yield ranging from 10.7 to 14.5 and from 7.8 to 9.6 t ha−1 for Bottelare and Beitem, respectively. Under favourable conditions, long fibre yields reached up to 2.4 t ha−1 for late-flowering and 2.1 t ha−1 for early- and mid-late-flowering varieties. In Western Europe, early to mid-late flowering varieties are generally favoured. Among these, the mid-late flowering variety Bialobrzeskie demonstrated strong yield potential. Overall, fibre quality across varieties was comparable to that of flax. Full article
(This article belongs to the Section Horticultural and Floricultural Crops)
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11 pages, 675 KiB  
Article
High Mortality of Huisache (Vachellia farnesiana) with Extreme Fire During Drought
by Victoria M. Donovan, Allie V. Schiltmeyer, Carissa L. Wonkka, Jacob Wagner, Devan A. McGranahan, William E. Rogers, Urs P. Kreuter and Dirac Twidwell
Fire 2025, 8(7), 242; https://doi.org/10.3390/fire8070242 - 21 Jun 2025
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Abstract
The almost complete eradication of fire from grasslands in North America has led to non-linear hysteretic transitions to shrub- and woodlands that the reintroduction of low-intensity fire is unable to reverse. We explore the ability of the extreme ends of variation in fire [...] Read more.
The almost complete eradication of fire from grasslands in North America has led to non-linear hysteretic transitions to shrub- and woodlands that the reintroduction of low-intensity fire is unable to reverse. We explore the ability of the extreme ends of variation in fire behavior to help overcome hysteretic threshold behaviors in huisache (Vachellia farnesiana) encroached grasslands. We contrasted experimental fire treatments with unburned control areas to assess the ability of extreme fires burned during drought to alter the density and structure of huisache. We found that extreme fires reduced the density of huisache by over 30% compared to control plots, both through driving huisache mortality and reducing the number of new recruits following treatments. For instance, extreme fire drove 48% huisache mortality compared to 4% in control treatments. For surviving plants, the number of stems increased but the crown area did not significantly change. Prescribed fire, conducted under the right conditions, can drive high mortality in one of the most notorious encroaching species in the southern U.S. Great Plains. With the fire conditions observed in this study likely to increase under future climate projections, utilizing extreme fire as a management tool for huisache will help scale up management to meet the growing extent of woody encroachment into grasslands. Full article
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