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Designing a Microfluidic Device with Integrated Ratiometric Oxygen Sensors for the Long-Term Control and Monitoring of Chronic and Cyclic Hypoxia
- Samantha M. Grist,
- Jonathan C. Schmok,
- Meng-Chi (Andy) Liu,
- Lukas Chrostowski and
- Karen C. Cheung
Control of oxygen over cell cultures in vitro is a topic of considerable interest, as chronic and cyclic hypoxia can alter cell behaviour. Both static and transient hypoxic levels have been found to affect tumour cell behaviour; it is potentially val...