Search Results (612)

Agricultural nondestructive testing technology is pivotal in safeguarding food quality assurance, safety monitoring, and supply chain transparency. While conventional optical methods such as near-infrared spectroscopy and hyperspectral imaging demonstrate proficiency in surface composition analysis, their constrained penetration depth and environmental sensitivity limit effectiveness in dynamic agricultural inspections. This review highlights the transformative potential of microwave technologies, systematically examining their operational principles, current implementations, and developmental trajectories for agricultural quality control. Microwave technology leverages dielectric response mechanisms to overcome traditional limitations, such as low-frequency penetration for grain silo moisture testing and high-frequency multi-parameter analysis, enabling simultaneous detection of moisture gradients, density variations, and foreign contaminants. Established applications span moisture quantification in cereal grains, oilseed crops, and plant tissues, while emerging implementations address storage condition monitoring, mycotoxin detection, and adulteration screening. The high-frequency branch of the microwave–millimeter wave systems enhances analytical precision through molecular resonance effects and sub-millimeter spatial resolution, achieving trace-level contaminant identification. Current challenges focus on three areas: excessive absorption of low-frequency microwaves by high-moisture agricultural products, significant path loss of microwave high-frequency signals in complex environments, and the lack of a standardized dielectric database. In the future, it is essential to develop low-cost, highly sensitive, and portable systems based on solid-state microelectronics and metamaterials, and to utilize IoT and 6G communications to enable dynamic monitoring. This review not only consolidates the state-of-the-art but also identifies future innovation pathways, providing a roadmap for scalable deployment of next-generation agricultural NDT systems. Full article

The abandoned goaf resulting from coal resource integration in China poses a significant threat to coal mine safety. The transient electromagnetic method (TEM) has emerged as a crucial technology for detecting goafs in coal mines due to its adaptable equipment and efficient implementation. In recent years, small-loop TEM has demonstrated high resolution and adaptability in challenging terrains with vegetation, such as coal mine ponding areas, karst regions, and reservoir seepage scenarios. By considering the sedimentary characteristics of coal seams and addressing the resistivity changes encountered in single-point inversion, a joint optimization inversion process incorporating lateral weighting factors and vertical roughness constraints has been developed to enhance the connectivity between adjacent survey points and improve the continuity of inversion outcomes. Through an OCCAM inversion approach, the regularization factor is dynamically determined by evaluating the norms of the data objective function and model objective function in each iteration, thereby reducing the reliance of inversion results on the initial model. Using the Xiaolong Coal Mine as a geological context, the impact of lateral and vertical weighting factors on the inversion outcomes of high- and low-resistivity structural models is examined through a control variable method. The analysis reveals that optimal inversion results are achieved with a combination of a lateral weighting factor of 0.5 and a vertical weighting factor of 0.1, ensuring both result continuity and accurate depiction of vertical and lateral electrical interfaces. The practical application of this approach validates its effectiveness, offering theoretical support and technical assurance for old goaf detection in coal mines, thereby holding significant engineering value. Full article

Background/Objectives: In many parts of the world, pharmacists hold the primary responsibility for providing safe and effective pharmacotherapy. A key aspect is the availability of appropriate medicines for each individual patient. When industrially manufactured medicines are unsuitable or unavailable, pharmacists can prepare tailor-made medicines. While this principle applies globally, practices vary between countries. In the Netherlands, the preparation of medicines in pharmacies is well-established and integrated into routine healthcare. This narrative review explores the role and significance of extemporaneous compounding, pharmacy preparations and related product care in the Netherlands. Methods: Pharmacists involved in pharmacy preparations across various professional sectors, including community and hospital pharmacies, central compounding facilities, academia, and the professional pharmacists’ organisation, provided detailed and expert insights based on the literature and policy documents while also sharing their critical perspectives. Results: We present arguments supporting the need for pharmacy preparations and examine their position and role in community and hospital pharmacies in the Netherlands. Additional topics are discussed, including the regulatory and legal framework, outsourcing, quality assurance, standardisation, education, and international context. Specific pharmacy preparation topics, often with a research component and a strong focus on product care, are highlighted, including paediatric dosage forms, swallowing difficulties and feeding tubes, hospital-at-home care, reconstitution of oncolytic drugs and biologicals, total parenteral nutrition (TPN), advanced therapy medicinal products (ATMPs), radiopharmaceuticals and optical tracers, clinical trial medication, robotisation in reconstitution, and patient-centric solid oral dosage forms. Conclusions: The widespread acceptance of pharmacy preparations in the Netherlands is the result of a unique combination of strict adherence to tailored regulations that ensure quality and safety, and patient-oriented flexibility in design, formulation, and production. This approach is further reinforced by the standardisation of a broad range of formulations and procedures across primary, secondary and tertiary care, as well as by continuous research-driven innovation to develop new medicines, formulations, and production methods. Full article

Detection of small vessels is of great significance for maritime safety assurance, abnormal vessel tracking, illegal fishing supervision, and combating smuggling. However, the radar reflection intensity of small vessels is low, making them difficult to detected with the radar’s constant false-alarm rate (CFAR) algorithm. To enhance the detection capability for small vessels, we propose an improved CFAR scheme. Specifically, we first compared traditional CFAR processing results of radar data with automatic identification system (AIS) data to identify some special targets. These special targets, which possessed AIS information, but remained undetected by radar, enabled an iTransformer model to generate more reasonable CFAR threshold adjustments. iTransformer adaptively lowered the threshold of the areas around these targets until they were detected by radar. This process made it easier to discover the small boats in the surrounding area. Experimental results showed that our method reduces the missed detection rate of small vessels by 73.4% and the false-alarm rate by 60.7% in simulated scenarios, significantly enhancing the CFAR detection capability. Overall, our study provides a new solution for ensuring maritime navigation safety and strengthening illegal supervision, while also offering new technical references for the field of radar detection. Full article

Accurate prediction of the F-factor averaged over one kilometer (FBAR), a critical wind shear metric, is essential for aviation safety. A central F-factor is used to compute FBAR. i.e., compute the value of FBAR at a point using a spatial interval beginning 500 m prior to the point and ending 500 m beyond the point. Traditional FBAR estimation using the Vicroy method suffers from limited vertical wind speed (W${\phantom{,}}_h$) accuracy, particularly in complex, non-idealized atmospheric conditions. This foundational study proposes a hybrid CNN-BiLSTM-Attention deep learning architecture that integrates spatial feature extraction, sequential dependency modeling, and attention mechanisms to address this limitation. The model was trained and evaluated on data generated by the industry-standard Airborne Doppler Weather Radar Simulation (ADWRS) system, using the DFW microburst case (C1-11) as a benchmark hazardous scenario. Following safety assurance principles aligned with SAE AS6983, the proposed model achieved a W${\phantom{,}}_h$ estimation RMSE (root-mean-squared deviation) of $0.623$ $\mathrm{m} {\mathrm{s}}^{-1}$ (vs. Vicroy’s $14.312$ $\mathrm{m} {\mathrm{s}}^{-1}$) and a correlation of 0.974 on 14,524 test points. This subsequently improved FBAR prediction RMSE by 98.5% (0.0591 vs. 4.0535) and MAE (Mean Absolute Error) by 96.1% (0.0434 vs. 1.1101) compared to Vicroy-derived values. The model demonstrated a 65.3% probability of detection for hazardous downdrafts with a low 1.7% false alarm rate. These results, obtained in a controlled and certifiable simulation environment, highlight deep learning’s potential to enhance the reliability of airborne wind shear detection for civil aircraft, paving the way for next-generation intelligent weather avoidance systems. Full article

The deformation characteristics of the surrounding rock in tunnel groups are considered critical for the design of support structures and the assurance of the long-term safety of deep-buried diversion tunnels. The deformation behavior of surrounding rock in tunnel groups was investigated to guide structural support design. Field tests and numerical simulations were performed to analyze the distribution of ground stress and the ground reaction curve under varying conditions, including rock type, tunnel spacing, and burial depth. A solid unit–structural unit coupled simulation approach was adopted to derive the two-liner support characteristic curve and to examine the propagation behavior of concrete cracks. The influences of surrounding rock strength, reinforcement ratio, and secondary lining thickness on the bearing capacity of the secondary lining were systematically evaluated. The following findings were obtained: (1) The tunnel group effect was found to be negligible when the spacing (D) was ≥65 m and the burial depth was 1600 m. (2) Both P_0.3 and P_max of the secondary lining increased linearly with reinforcement ratio and thickness. (3) For surrounding rock of grade III (IV), 95% u_lim and 90% u_lim were found to be optimal support timings, with secondary lining forces remaining well below the cracking stress during construction. (4) For surrounding rock of grade V in tunnels with a burial depth of 200 m, 90% u_lim is recommended as the initial support timing. Support timings for tunnels with burial depths between 400 m and 800 m are 40 cm, 50 cm, and 60 cm, respectively. Design parameters should be adjusted based on grouting effects and monitoring data. Additional reinforcement is recommended for tunnels with burial depths between 1000 m and 2000 m to improve bearing capacity, with measures to enhance impermeability and reduce external water pressure. These findings contribute to the safe and reliable design of support structures for deep-buried diversion tunnels, providing technical support for design optimization and long-term operation. Full article

Autonomous earthwork machinery is gaining traction as a means to boost productivity and safety on space-constrained urban sites, yet the fast-growing literature has not been fully integrated. To clarify current knowledge, we systematically searched Scopus and screened 597 records, retaining 157 peer-reviewed papers (2015–March 2025) that address autonomy, integrated control, or risk mitigation for excavators, bulldozers, and loaders. Descriptive statistics, VOSviewer mapping, and qualitative synthesis show the output rising rapidly and peaking at 30 papers in 2024, led by China, Korea, and the USA. Four tightly linked themes dominate: perception-driven machine autonomy, IoT-enabled integrated control systems, multi-sensor safety strategies, and the first demonstrations of fleet-level collaboration (e.g., coordinated excavator clusters and unmanned aerial vehicle and unmanned ground vehicle (UAV–UGV) site preparation). Advances include centimeter-scale path tracking, real-time vision-light detection and ranging (LiDAR) fusion and geofenced safety envelopes, but formal validation protocols and robust inter-machine communication remain open challenges. The review distils five research priorities, including adaptive perception and artificial intelligence (AI), digital-twin integration with building information modeling (BIM), cooperative multi-robot planning, rigorous safety assurance, and human–automation partnership that must be addressed to transform isolated prototypes into connected, self-optimizing fleets capable of delivering safer, faster, and more sustainable urban construction. Full article

Background/Objectives: Proton therapy delivers highly conformal doses to the target area without producing an exit dose, minimizing cumulative doses to healthy liver tissue. This study aims to evaluate current practices, challenges, and variations in the implementation of proton stereotactic body radiation therapy (SBRT) and hypofractionated therapy for liver malignancies, with the goal of providing a technical assessment to promote broader adoption and support future clinical trials. Methods and Materials: An extensive survey was conducted by NRG Oncology across North American proton treatment centers to assess the current practices of proton liver SBRT and hypofractionated therapy. The survey focused on key aspects, including patient selection, prescription and normal tissue constraints, simulation and motion management, treatment planning, quality assurance (QA), treatment delivery, and the use of image-guided radiation therapy (IGRT). Results: This survey captures the current practice patterns and status of proton SBRT and hypofractionated therapy in liver cancer treatment.  Proton therapy is increasingly preferred for treating inoperable liver malignancies due to its ability to minimize healthy tissue exposure. However, the precision required for proton therapy presents challenges, particularly in managing uncertainties and target motion during high-dose fractions and short treatment courses. Survey findings revealed significant variability in clinical practices across centers, highlighting differences in motion management, dose fractionation schedules, and QA protocols. Conclusion: Proton SBRT and hypofractionated therapy offer significant potential for treating liver malignancies. A comprehensive approach involving precise patient selection, treatment planning, and QA is essential for ensuring safety and effectiveness. This survey provides valuable insights into current practices and challenges, offering a foundation for technical recommendations to optimize the use of proton therapy and guide future clinical trials. Full article

Microbiological contamination of food remains a critical global public health concern, contributing to millions of foodborne illness cases each year. Traditional diagnostic methods, particularly culture-based techniques, have been widely employed but are often limited by low sensitivity, insufficient specificity, and lengthy turnaround times. Recent advances in molecular biology, biosensor technology, and analytical chemistry have enabled the development of more rapid and precise diagnostic tools. Among these, Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) has emerged as a transformative method for microbial identification. This review provides a comprehensive overview of the current applications of MALDI-TOF MS in the diagnosis of microbiological contamination in food. The method offers rapid, accurate, and cost-effective identification of microorganisms and is increasingly used in food safety laboratories for the detection of foodborne pathogens, ensuring the safety and quality of food products. We highlight the fundamental principles of MALDI-TOF MS, discuss its methodologies, and examine its advantages, limitations, and future prospects in food microbiology and quality assurance. Full article

The Chinese mitten crab (Eriocheir sinensis) industry is currently facing the challenges of origin fraud, as well as a lack of precision and interpretability of existing traceability methods. Here, we propose a high-precision origin traceability method based on a combination of stable isotope analysis and interpretable machine learning. We sampled Chinese mitten crabs from six origins representing diverse aquatic environments and farming practices, and analyzed their δ¹³C, δ¹⁵N, δ²H, and δ¹⁸O stable isotope compositions in different sexes and tissues (hepatopancreas, muscle, and gonad). By comparing the classification performance of Random Forest, XGBoost, and Logistic Regression models, we found that the Random Forest model outperformed the others, achieving high accuracy (91.3%) in distinguishing samples from different origins. Interpretation of the optimal Random Forest model, using SHAP (SHapley Additive exPlanations) analysis, identified δ²H in male muscle, δ¹⁵N in female hepatopancreas, and δ¹³C in female hepatopancreas as the most influential features for discriminating geographic origin. This analysis highlighted the crucial role of environmental factors, such as water source, diet, and trophic level, in origin discrimination and demonstrated that isotopic characteristics of different tissues provide unique discriminatory information. This study offers a novel paradigm for stable isotope traceability based on explainable machine learning, significantly enhancing the identification capability and reliability of Chinese mitten crab origin traceability, and holds significant implications for food safety assurance. Full article

Autonomous Parking Systems (APSs) are rapidly evolving, promising enhanced convenience, safety, and efficiency. This review critically examines the current strategies in perception, path planning, and vehicle control, alongside system-level aspects like integration, validation, and security. While significant progress has been made, particularly with the advent of deep learning and sophisticated sensor fusion, formidable challenges persist. This paper delves into the inherent trade-offs, such as balancing computational cost with real-time performance demands; unresolved foundational issues, including the verification of non-deterministic AI components; and the profound difficulty of ensuring robust real-world deployment across diverse and unpredictable conditions, ranging from cluttered urban canyons to poorly lit, ambiguously marked parking structures. We also explore the limitations of current technologies, the complexities of safety assurance in dynamic environments, the pervasive impact of cost considerations on system capabilities, and the critical, often underestimated, need for genuine user trust. Future research must address not only these technological gaps with innovative solutions but also the intricate socio-technical dimensions to realize the full potential of APS. Full article

Integrating Industry 4.0 technologies into food manufacturing processes transforms traditional quality management practices. This study aims to understand how these technologies are applied across managerial quality functions in the food industry. A systematic literature review was conducted using the Scopus and Web of Science databases, selecting 69 peer-reviewed articles. The analysis identified quality control (QC) and quality assurance (QA) as the most frequently addressed functions. Sensor technology was the most cited, followed by blockchain and artificial intelligence, mainly supporting food safety, process monitoring, and traceability. In contrast, quality design (QD), quality improvement (QI), and quality policy and strategy (QPS) were underrepresented, revealing a gap in strategic and innovation-focused applications. Based on these insights, the Food Quality Management 4.0 (FQM 4.0) framework was developed, mapping the relationship between Industry 4.0 technologies and the five managerial quality functions, with food safety positioned as a transversal dimension. The framework contributes to academia and industry by offering a structured view of technological integration in food quality management and identifying future research and implementation directions. This study highlights the need for broader adoption of advanced technologies to improve transparency, responsiveness, and overall quality performance in the food sector. Full article

The Shenfu Gas Field faces challenges with uneven wellhead pressures, where low-pressure wells lose discharge capacity and high-pressure wells require throttling, leading to significant energy waste. Ejectors offer potential for energy recovery by utilizing high-pressure gas to boost low-pressure production. A computational fluid dynamics (CFD) model was developed using simulation software to simulate ejector performance. Parametric studies analyzed key structural parameters (mixing chamber length L_m, diameter D_m, nozzle spacing L_c, diffuser length L_d) and operational variables (compression ratio, working/entrained fluid pressures). Model validity was confirmed via grid independence tests and experimental comparisons (error < 10%). Network-level efficacy was verified using pipeline simulation software. Entrainment ratio (ε) and isentropic efficiency (η) exhibited non-linear relationships with structural parameters, with distinct optima depending on compression ratio. D_m had the strongest influence on ε. Higher compression ratios reduced ε, while increasing working fluid pressure or entrained fluid pressure improved ε. Optimal configurations were identified. Network simulations confirmed functional effectiveness, though efficiency diminished over production time. Ejector efficiency is highly sensitive to specific structural and operational parameters. Deployment in gas gathering networks is viable but most beneficial in early production stages. Full article

Carbon Capture and Storage (CCS) is a key technology for reducing anthropogenic greenhouse gas emissions, in which pipelines play a vital role in transporting CO₂ captured from industrial emitters to geological storage sites. To aid the efficient and safe operation of the CO₂ transport infrastructure, robust, accurate, and reliable solutions for monitoring pipelines transporting industrial CO₂ streams are urgently needed. This literature review study summarizes the monitoring objectives and identifies the problems and relevant mathematical algorithms developed for optimization of monitoring systems for pipeline transportation of water, oil, and natural gas, which can be relevant to the future CO₂ pipelines and pipeline networks for CCS. The impacts of the physical properties of CO₂ and complex designs and operation scenarios of CO₂ transport on the pipeline monitoring systems design are discussed. It is shown that the most relevant to liquid- and dense-phase CO₂ transport are the sensor placement optimization methods developed in the context of detecting leaks and flow anomalies for water distribution systems and pipelines transporting oil and petroleum liquids. The monitoring solutions relevant to flow assurance and monitoring impurities in CO₂ pipelines are also identified. Optimizing the CO₂ pipeline monitoring systems against several objectives, including the accuracy of measurements, the number and type of sensors, and the safety and environmental risks, is discussed. Full article